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Thiosemicarbazide

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Identification
Molecular formula
C2H8N4S
CAS number
79-19-6
IUPAC name
N-[4-[[[amino(sulfanyl)methylene]hydrazono]methyl]phenyl]acetamide
State
State

Thiosemicarbazide is generally solid at room temperature. It is stable under normal conditions but should be protected from moisture.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
119.17g/mol
Molar mass
119.1650g/mol
Density
1.4050g/cm3
Appearence

Thiosemicarbazide appears as colorless or white crystals. It tends to be odorless and is often encountered in the form of crystalline powder.

Comment on solubility

Solubility of N-[4-[[[amino(sulfanyl)methylene]hydrazono]methyl]phenyl]acetamide

N-[4-[[[amino(sulfanyl)methylene]hydrazono]methyl]phenyl]acetamide is a complex organic compound with intriguing solubility characteristics. Understanding its solubility is crucial for applications in pharmaceutical and chemical research.

  • Polar vs. Non-Polar: The presence of the amino and sulfanyl groups indicates that this compound may exhibit polarity, suggesting solubility in polar solvents such as water or alcohol.
  • pH Sensitivity: Being an amide, the solubility might be pH-dependent, potentially increasing in acidic conditions due to protonation of the amino group, which could enhance its interaction with solvent molecules.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the amino functionality may facilitate solubility in polar solvents, leading to increased dissolution rates.
  • Temperature Influence: Generally, solubility tends to increase with temperature; hence, heating the solvent might improve the solubility of this compound.

However, the exact solubility can vary significantly based on factors such as solvent choice and temperature. Experimentation or detailed literature studies are often required to ascertain precise solubility data for this compound. To quote scientific principles: "Solubility is the key gatekeeper for compound applications in biological systems."


In conclusion, while exact data might not be readily available, understanding the factors affecting solubility provides a foundation for exploring N-[4-[[[amino(sulfanyl)methylene]hydrazono]methyl]phenyl]acetamide in various chemical environments.

Interesting facts

Interesting Facts About N-[4-[[[Amino(sulfanyl)methylene]hydrazono]methyl]phenyl]acetamide

N-[4-[[[Amino(sulfanyl)methylene]hydrazono]methyl]phenyl]acetamide is a compound that sparks interest within the realms of medicinal and organic chemistry. Here are some captivating aspects of this intriguing molecule:

  • Versatile Applications: This compound is noteworthy for its potential therapeutic uses, especially in the area of pharmaceuticals. Its unique structure allows it to interact with biological systems in unique ways.
  • Chemical Characterization: The presence of the hydrazone group contributes to the compound's reactivity, making it a subject of study for various chemical reactions, including condensation and substitution processes.
  • Biological Significance: Given the amino and sulfanyl functionalities, researchers are investigating the compound’s role in biological activities, such as antimicrobial and antitumor properties.
  • Synthetic Pathways: The synthesis of this compound often involves intricate organic reactions, showcasing the creativity and skill required in modern synthetic organic chemistry. Students and chemists enjoy exploring various synthetic routes to optimize yields and purity.
  • Structural Complexity: The compound's structure, featuring multiple functional groups and a phenyl ring, provides rich opportunities for studying steric and electronic effects in chemical reactions.

As one dives deeper into the study of N-[4-[[[Amino(sulfanyl)methylene]hydrazono]methyl]phenyl]acetamide, it’s clear that it serves as a bridge between fundamental chemistry and real-world applications. "Chemistry is the study of transformations," and this compound exemplifies that notion beautifully through its diverse potential uses and avenues for exploration.