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Thiamine disulfide

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Identification
Molecular formula
C24H34N8O4S2
CAS number
67-75-2
IUPAC name
N-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-N-[2-[[2-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-1-(2-hydroxyethyl)prop-1-enyl]disulfanyl]-4-hydroxy-1-methyl-but-1-enyl]formamide
State
State

Solid at room temperature.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
354.00
Boiling point (Kelvin)
627.15
General information
Molecular weight
594.72g/mol
Molar mass
594.7150g/mol
Density
1.3000g/cm3
Appearence

Thiamine disulfide appears as a white to off-white crystalline powder. It is typically odorless and tasteless. When exposed to air, it may gradually deteriorate due to its instability, especially in the presence of moisture.

Comment on solubility

Solubility of N-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-N-[2-[[2-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-1-(2-hydroxyethyl)prop-1-enyl]disulfanyl]-4-hydroxy-1-methyl-but-1-enyl]formamide (C24H34N8O4S2)

The solubility of this complex compound is influenced by its intricate structure and the presence of multiple functional groups. Here are some key points regarding its solubility:

  • Hydrophilicity vs. Hydrophobicity: The presence of amino groups and hydroxyl groups generally enhances solubility in polar solvents like water. Conversely, the organic portions of the molecule may exhibit hydrophobic characteristics, making solubility in non-polar solvents more favorable.
  • Effects of pH: Due to the presence of amine and hydroxyl groups, the solubility may vary significantly with pH. For instance, at acidic pH values, protonation of the amino groups can increase solubility.
  • Solvent Compatibility: This compound is likely to be soluble in a range of organic solvents, particularly those with polar characteristics, such as methanol, ethanol, or dimethyl sulfoxide (DMSO).

As always, it’s crucial to conduct experimental solubility testing under controlled conditions, as predicted solubility may not always translate directly to practical outcomes. Understanding the solubility profile is essential for applications in drug formulation and chemical synthesis.

Interesting facts

Interesting Facts about N-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-N-[2-[[2-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-1-(2-hydroxyethyl)prop-1-enyl]disulfanyl]-4-hydroxy-1-methyl-but-1-enyl]formamide

This compound is a fascinating example of molecular complexity, characterized by intricate structural features and potential biological activity. Here are some engaging facts about this compound:

  • Biological Relevance: Due to the presence of the 4-amino-2-methyl-pyrimidin-5-yl moiety, this compound is of great interest in medicinal chemistry, often being studied for its potential applications as an anti-cancer or anti-viral agent.
  • Structural Complexity: The molecule features various unique functional groups, including disulfide, hydroxyl, and amide groups, which contribute to its reactivity and solubility properties.
  • Potential as a Bioactive Agent: The intricate arrangement of atoms may play a role in its interaction with biological targets, making it a subject of research in drug design.
  • Design and Synthesis: The synthesis of this compound can be both challenging and rewarding, often requiring advanced organic chemistry techniques that highlight the importance of precision in reaction conditions.
  • Therapeutic Applications: Compounds of this nature may be explored for their ability to deliver therapeutic agents directly to specific tissues, enhancing efficacy while reducing side effects, a strategy known as targeted therapy.

In the words of a famous chemist, "The most beautiful thing we can experience is the mysterious. It is the source of all true art and science." This quote resonates with the ongoing research surrounding complex organic compounds like this one, as each discovery brings us closer to unlocking the mysteries surrounding their functions and applications.

As we continue to unravel the complexities of compounds such as N-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-N-[2-[[2-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-1-(2-hydroxyethyl)prop-1-enyl]disulfanyl]-4-hydroxy-1-methyl-but-1-enyl]formamide, we are reminded of the incredible potential that lies within the molecular world.

Synonyms
thiamine disulfide
67-16-3
DTXSID6046890
Formamide, N,N'-(dithiobis(2-(2-hydroxyethyl)-1-methyl-2,1-ethenediyl))bis(N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-
N-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-N-[(2Z)-3-{[(2E)-2-{N-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]FORMAMIDO}-5-HYDROXYPENT-2-EN-3-YL]DISULFANYL}-5-HYDROXYPENT-2-EN-2-YL]FORMAMIDE
SCHEMBL397373
CHEMBL3188440
DB-054994
NS00078953