Interesting facts
Interesting Facts about N-[4-(Acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide
N-[4-(Acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide is an intriguing compound that has garnered attention in the field of medicinal chemistry. Here are some noteworthy facts:
- Versatile Applications: This compound possesses properties that make it a potential candidate for pharmaceutical applications, particularly in the realm of cancer research and treatment due to its unique molecular structure.
- Mechanism of Action: The acridine moiety in the compound is reminiscent of many DNA-acting drugs. These types of compounds can intercalate into DNA, which may lead to an inhibition of cancer cell growth.
- Sulfonamide Feature: The presence of the sulfonamide group enhances the compound's solubility and can improve its pharmacokinetic properties, making it easier for the drug to reach its targets in the body.
- Research Interest: Studies on this compound are still ongoing, as researchers are keen to explore its efficacy and mechanism. As highlighted by one researcher: "Compounds like this hold the key to unlocking new cancer therapies."
- Pioneering Structure: The combination of acridine and methanesulfonamide provides a framework for further modifications, thereby enabling the development of more potent derivatives useful in various medical fields.
In summary, N-[4-(Acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide represents a significant topic of study in drug design and development. Its unique structural characteristics and potential applications in targeting cancer cells stand as a testament to the innovative nature of modern chemistry.
Synonyms
amsacrine
51264-14-3
Amsidine
m-AMSA
Amsidyl
Acridinylanisidide
Amsacrina
Lamasine
Amekrin
mAMSA
Amsacrinum
Acridinyl Anisidide
meta-Amsacrine
amsidil
Amsine
4'-(9-Acridinylamino)methanesulfon-m-anisidide
AMSA
Amsacrinum [INN-Latin]
Amsacrina [INN-Spanish]
SN-11841
4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide
NSC-249992
N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
4'-(9-Acridinylamino)methanesulphon-m-anisidide
CI-880
NSC249992
NSC 156303
NSC 249992
NSC-156303
Methanesulfonamide, N-[4-(9-acridinylamino)-3-methoxyphenyl]-
Amsidyl (TN)
SN 21429
4'-(9-Acridinylamino)methanesulfon-meta-anisidide
N-(4-(Acridin-9-ylamino)-3-methoxyphenyl)methanesulfonamide
CCRIS 1027
HSDB 7087
m-AMSA;acridinyl anisidide
EINECS 257-094-3
00DPD30SOY
CI 880
Amsacrine [USAN:INN:BAN]
N-(4-(9-Acridinylamino)-3-methoxyphenyl)methanesulfonamide
N-[4-(9-Acridinylamino)-3-methoxyphenyl]methanesulfonamide
BRN 0500176
CHEBI:2687
Methanesulfonamide, N-(4-(9-acridinylamino)-3-methoxyphenyl)-
AMSACRINE [INN]
AMSACRINE [MI]
Methanesulfonanilide, 4'-(9-acridinylamino)-3'-methoxy-
AMSACRINE [HSDB]
AMSACRINE [IARC]
AMSACRINE [USAN]
CHEMBL43
AMSACRINE [VANDF]
AMSACRINE [MART.]
NCI-249992
AMSACRINE [WHO-DD]
Methanesulfon-m-anisidide, 4'-(9-acridinylamino)-
SN-21429
DTXSID4022604
Cain's Acridine
5-22-11-00030 (Beilstein Handbook Reference)
meta-AMSA
AMSA P-D
AMSACRINE (IARC)
Amsacrinum (INN-Latin)
N-[4-(acridin-9-ylamino)-3-(methyloxy)phenyl]methanesulfonamide
Amsacrina (INN-Spanish)
N-{4-[(ACRIDIN-9-YL)AMINO]-3-METHOXYPHENYL}METHANESULFONAMIDE
NSC156303
AMSACRINE (MART.)
C21H19N3O3S
m-AMSA hydrochloride; acridinyl anisidide hydrochloride
Amecrin
Cains Acridine
Cain Acridine
MLS002153376
meta AMSA
nAMSA
SN11841
AMSA PD
Amsacrine (USAN/INN)
AMSA P D
SMR000875352
UNII-00DPD30SOY
AMSA, M-
N-(4-((acridin-9-yl)amino)-3-methoxyphenyl)methanesulfonamide
ASW
MFCD00242748
Amsacrine (Standard)
Lopac-A-9809
NCIMech_000607
Neuro_000118
SCHEMBL4047
Lopac0_000154
MLS006010099
cid_148673
DTXCID002604
BDBM87351
HMS3748E05
N-[4-(9-Acridinylamino)-3-methoxy-phenyl]methanesulfonamide
BCP08958
CCG-35555
HY-13551R
AKOS015917522
CS-1942
DB00276
SDCCGSBI-0050142.P003
NCGC00015113-01
NCGC00015113-02
NCGC00015113-03
NCGC00015113-04
NCGC00093644-07
NCGC00093644-10
NCGC00162077-01
AS-11665
DA-50187
HY-13551
NCI60_001995
SMR000857391
WLN: T C666 BNJ IMR BO1 DMSW1
DB-082052
NS00008525
C01553
C75400
D02321
4'-(9-Acridinylamino)methane-sulfon-m-anisidide
4'-(9-Acridinylamino)methanesulfonyl m-anisidide
EN300-7481264
4'-(9-Acridinylamino)-methylsulfonyl-m-anisidine
4'-(9-Acridinylamino)-3'-methoxymethanesulfonanlide
Q2784004
BRD-K68346641-001-01-4
BRD-K68346641-001-02-2
Methanesulfonanilide,4'-(9-acridinylamino)-3'methoxy-
N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide;hydrochloride
N-[4-(acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide;hydrochloride
257-094-3
Solubility of N-[4-(acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide
The solubility of N-[4-(acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide (C21H19N3O3S) varies significantly depending on the solvent used and the conditions applied. Generally, this compound can be considered to have the following solubility characteristics:
It is essential to conduct solubility tests under controlled conditions to determine the exact solubility profile of this compound. Factors such as temperature and the presence of co-solvents can also impact its solubility behavior. Remember, the phrase “solubility is key” can often dictate the application and efficacy of compounds in various chemical and biological systems.