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Adrenalone

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Identification
Molecular formula
C9H11NO3
CAS number
54-15-3
IUPAC name
N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide
State
State

Adrenalone is generally found in a solid state at room temperature. It is used primarily in its hydrochloride form, which is also solid and crystalline.

Melting point (Celsius)
149.00
Melting point (Kelvin)
422.00
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.00
General information
Molecular weight
167.19g/mol
Molar mass
167.1760g/mol
Density
1.3000g/cm3
Appearence

Adrenalone hydrochloride appears as a white to off-white powder. It is typically crystalline in nature and is soluble in water.

Comment on solubility

Solubility of N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide

The solubility of N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide (C9H11NO3) can vary based on several factors, including temperature and the solvent used. Generally speaking:

  • Polar solvents: This compound is expected to have moderate solubility in polar solvents such as water and methanol due to its ability to form hydrogen bonds.
  • Non-polar solvents: Its solubility in non-polar solvents like hexane is likely to be quite low, owing to the hydrophilic nature of the hydroxyl groups present in its structure.
  • Effect of temperature: Increased temperatures may enhance solubility, promoting molecular interactions that can aid in dissolving the compound in various solvents.

In conclusion, while N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide displays some degree of solubility in polar environments, it is less compatible with non-polar substances. This property is crucial for its applications and behavior in chemical formulations.

Interesting facts

Interesting Facts about N-(3,4-Dihydroxyphenyl)-N-methyl-nitrous Amide

N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide, often referred to in the literature as a nitroso compound, presents intriguing characteristics that warrant exploration. Here are some captivating facts regarding this compound:

  • Biological Significance: This compound is known to exhibit biological activities, which can include antioxidant properties. Antioxidants are crucial for combatting oxidative stress in cells, potentially mitigating various diseases.
  • Chemical Behavior: The presence of both an amide group and a nitroso functional group in its structure implies unique reactivity. Nitroso compounds can participate in reactions leading to diazonium ions, which are intermediates in various synthetic pathways.
  • Structural Features: The 3,4-dihydroxyphenyl part of the molecule indicates the presence of hydroxyl groups that can engage in hydrogen bonding, influencing solubility and molecular interactions.
  • Potential Applications: Given its structural composition, this compound might find applications in pharmaceuticals, particularly in drug design where enhancing bioavailability and targeting specific biochemical pathways are essential.
  • Chemistry of Nitroso Compounds: Nitroso compounds are notable in organic synthesis for their versatility. They can be used in the synthesis of various functional groups, making them valuable in the synthetic chemist’s toolkit.

In summary, N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide is more than just a simple compound; it represents a bridge between chemistry and biology. Its unique structure and properties open doors to fascinating research and potential real-world applications, highlighting the importance of exploring the relationships between molecular structure and functionality.

Synonyms
3,4-dephostatin
Me-3,4-dephostatin
3,4-Dihydroxy-N-methyl-N-nitrosoaniline
Methyl-3,4-dephostatin
173043-84-0
4-[methyl(Nitroso)amino]benzene-1,2-Diol
N-(3,4-Dihydroxyphenyl)-N-methylnitrous amide
Lopac-M-9440
L2037 (beta-lapachone)
P00017
Lopac0_000871
MN30
SCHEMBL3894012
CHEMBL1256623
SCHEMBL13448407
BDBM81347
EU0100871_PURCHASED
DTXSID801017608
GLXC-15488
HMS3262P03
Tox21_500871
HSCI1_000165
3,4-Dihydroxy-N-methyl-N-nitrosaline
AKOS006275313
CCG-204953
LP00871
SDCCGSBI-0050846.P002
NCGC00015706-01
NCGC00015706-02
NCGC00015706-03
NCGC00015706-04
NCGC00094195-01
NCGC00094195-02
NCGC00261556-01
HY-124152
EU-0100871
M9440
M 9440
Methyl-3,4-dephostatin, >98% (HPLC), powder
N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide
SR-01000076015
SR-01000076015-1
Q27464530