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Acetazolamide

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Identification
Molecular formula
C4H6N4O3S2
CAS number
59-66-5
IUPAC name
N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium-2-yl)acetamide
State
State

At room temperature, acetazolamide is in a solid state. It is typically used in its powdered form for pharmaceutical preparations.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.00
Boiling point (Celsius)
278.00
Boiling point (Kelvin)
551.00
General information
Molecular weight
222.25g/mol
Molar mass
222.2450g/mol
Density
1.6500g/cm3
Appearence

Acetazolamide typically appears as a white or nearly white crystalline powder. It is odorless and has a slightly acidic taste. Due to its crystalline nature, it can reflect light to some extent, making it resemble many other pharmaceutical compounds in appearance.

Comment on solubility

Solubility of N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium-2-yl)acetamide

The solubility of the compound N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium-2-yl)acetamide (C4H6N4O3S2) presents interesting characteristics influenced by its diverse functional groups and molecular structure.

To understand its solubility, consider the following key factors:

  • Polarity: The presence of sulfonamide and thiadiazole groups contributes to the overall polarity of the molecule. This impacts its ability to interact with polar solvents, enhancing solubility in water.
  • Temperature: Increased temperatures often improve solubility for many compounds. Hence, elevated temperatures may increase the solubility of this particular compound.
  • pH Levels: Since this compound contains a thiadiazole ring and sulfonamide groups, its solubility may be affected by the pH of the solvent, where changes can lead to ionization, thus influencing solubility rates.
  • Solvent Type: Organic solvents might have a varied effect on solubility compared to water. Non-polar solvents may not dissolve the compound effectively due to its polar character.

In conclusion, while the specific solubility parameters may vary, the compound is expected to be soluble in polar solvents, especially water, indicating its potential utility in various chemical applications where solubility is a crucial parameter.

Interesting facts

Interesting Facts about N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium-2-yl)acetamide

N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium-2-yl)acetamide is a compound that occupies a unique niche in the world of pharmaceuticals and agrochemicals. Here are some fascinating insights that highlight its significance:

  • Biological Activity: This compound has shown potential as an antibacterial agent. Its structure allows it to inhibit the growth of specific bacterial strains, making it valuable in drug development.
  • Thiadiazole Derivatives: The thiadiazole ring present in this compound is known for its versatility in medicinal chemistry. Compounds containing this heterocyclic moiety often exhibit a range of biological activities, including antifungal and antiviral effects.
  • Sulfonamide Linkage: The sulfamoyl group enhances the solubility and efficacy of the compound. Sulfonamides have historically been key in the development of antibiotics, paving the way for modern medicinal chemistry.
  • Research Interests: As a subject of ongoing research, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium-2-yl)acetamide is often investigated for its chemical properties, interactions, and potential therapeutic uses.

In the realm of chemistry, the synthesis of such compounds is intriguing. Scientists explore various synthetic routes to optimize yield and purify the product while maintaining its biological activity. The study of compounds like this not only expands our understanding of chemical entities but also opens doors for innovative drug development.

As noted by chemists, "The intricate design of small molecules can lead to breakthroughs in healthcare, especially in creating targeted therapies." Unfortunately, the journey from laboratory to clinical application is often a long one, filled with extensive research and testing. Nevertheless, the potential of compounds like N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium-2-yl)acetamide keeps the scientific community engaged and motivated.

Synonyms
MZM
3daz
3dcs