Cl-Quinazolin-4-amine

Exploring N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine

N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine is a fascinating compound with a rich potential in medicinal chemistry. Here are some intriguing facts about this molecule:

• Pharmacological Potential: This compound belongs to the quinazoline family, which is known for its various biological activities. Quinazolines have been reported to possess antitumor, antiviral, and antimicrobial properties.
• Chlorine Substitution: The presence of the 3-chloro group on the phenyl ring greatly influences the compound's electronic properties, enhancing its ability to interact with biological targets.
• Methoxy Groups: The dimethoxy substituents at positions 6 and 7 are known to contribute to the lipophilicity of the compound, affecting its absorption and distribution in biological systems.
• Structure-Activity Relationship (SAR): Understanding how different substituents, like the chlorine and methoxy groups, alter the compound's efficacy is critical in drug design. It provides insights into optimizing therapeutic agents.
• Pivotal in Research: Compounds like this serve as key intermediates for synthesizing more complex molecules, making them valuable in ongoing research for developing new drugs.

In summary, N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine showcases the intricate balance of chemical structure and biological function. Such compounds are essential in the search for new therapeutic agents that can combat various diseases.