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Glutathione Disulfide

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Identification
Molecular formula
C20H32N6O12S2
CAS number
70-18-8
IUPAC name
N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethyl-butanoyl)amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxo-propyl]-2,4-dihydroxy-3,3-dimethyl-butanamide
State
State

At room temperature, glutathione disulfide is a solid.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
612.64g/mol
Molar mass
612.6360g/mol
Density
1.4592g/cm3
Appearence

Glutathione disulfide is typically a white to off-white powder. It is a relatively stable compound, though it may decompose on exposure to moisture or when subjected to excessively high temperatures.

Comment on solubility

Solubility of N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethyl-butanoyl)amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxo-propyl]-2,4-dihydroxy-3,3-dimethyl-butanamide (C20H32N6O12S2)

The solubility profile of N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethyl-butanoyl)amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxo-propyl]-2,4-dihydroxy-3,3-dimethyl-butanamide can be complex due to its multifaceted structure, which includes:

  • Multiple functional groups
  • Hydroxyl (-OH) groups that can create hydrogen bonds
  • Disulfide links that influence polarity

As a result, this compound exhibits variable solubility characteristics depending on the solvent:

  1. Aqueous solution: The presence of hydroxyl groups indicates potential for reasonable solubility in water, particularly at elevated temperatures.
  2. Organic solvents: This compound may have enhanced solubility in polar organic solvents due to its unique hydrophilic and lipophilic balance.

It is important to note that solubility may also be affected by:

  • pH of the solution
  • Presence of salts or other ions

In summary, while N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethyl-butanoyl)amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxo-propyl]-2,4-dihydroxy-3,3-dimethyl-butanamide shows potential for solubility in both aqueous and organic solvents, the actual solubility values should be evaluated through experimental data for precise applications.

Interesting facts

Interesting Facts about N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethyl-butanoyl)amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxo-propyl]-2,4-dihydroxy-3,3-dimethyl-butanamide

This compound, with its intricate structure, is a fine example of how complex chemical architecture can play a pivotal role in biological applications. Here are some compelling facts about it:

  • Biological Importance: This compound is of significant interest in medicinal chemistry and pharmacology due to its potential role in therapeutic applications. Its structure allows for interactions with various biological targets, potentially enhancing drug efficacy.
  • Disulfide Linkage: Featuring a disulfide bond in its architecture, the compound exhibits unique redox properties that can influence its stability and activity, making it a topic of study in the field of biochemical research.
  • Hydroxyl Groups: The presence of multiple hydroxyl groups (–OH) contributes to its hydrophilicity and may enhance solubility in biological fluids, impacting its absorption and distribution within living organisms.
  • Structure-Activity Relationship (SAR): Its complex layered structure allows chemists to investigate the relationship between its chemical composition and biological activity, supporting the design of more targeted analogs.
  • Potential Applications: Researchers are exploring the compound's derivatives for use in various fields, including drug development for diseases such as cancer and diabetes, owing to its promising bioactive properties.

Overall, N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethyl-butanoyl)amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxo-propyl]-2,4-dihydroxy-3,3-dimethyl-butanamide stands as a testament to the fascinating world of chemical compounds and their potential impact on science and medicine. As scientists continue to unravel its properties, we anticipate exciting developments that could change the landscape of therapeutic interventions.

Synonyms
138148-35-3
Bis(N-pantothenylamidoethyl) disulfide
N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
Pantosin (TN)
Pantethine (JP17)
Butanamide, N,N'-[dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethyl- (9CI)
D-pantethine anhydrous
D-Pantethine;LBF disulfide
SR-05000002047
SCHEMBL59597
CHEMBL3184321
CHEBI:181909
DTXSID801015707
HMS3264G11
Pharmakon1600-01505920
NSC759269
CCG-213994
DA-52680
SBI-0207047.P001
NS00003134
D01234
AB01563241_01
SR-05000002047-1
SR-05000002047-2
SR-05000002047-3
BRD-A76244192-001-01-6
BRD-A76244192-001-02-4
N,N'-{Disulfanediylbis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]}bis(2,4-dihydroxy-3,3-dimethylbutanamide)
N-[3-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]propanoylamino]ethyldisulanyl]ethylamino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide