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Tiapride

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Identification
Molecular formula
C15H24N2O2
CAS number
51012-33-0
IUPAC name
N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
State
State
Solid
Melting point (Celsius)
101.00
Melting point (Kelvin)
374.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
264.37g/mol
Molar mass
317.4400g/mol
Density
1.0900g/cm3
Appearence

Tiapride typically appears as a white or almost white crystalline powder. It is often available in its hydrochloride form in pharmaceutical formulations.

Comment on solubility

Solubility of N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide

The solubility of N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide (C15H24N2O2) can be influenced by several factors due to its complex structure. Understanding its solubility is crucial for various applications, especially in pharmaceuticals, where solubility can affect bioavailability.

Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups such as amides can increase solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the amide group to form hydrogen bonds can enhance solubility in aqueous solutions.
  • Hydrophobic Interactions: The hydrocarbon portions of the molecule may impart hydrophobic characteristics, potentially reducing solubility in polar solvents.
  • Temperature: As with many compounds, solubility may increase with rising temperature.

In summary, while N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide is likely to exhibit moderate solubility due to its polar amide functional group, the exact solubility profile can vary significantly based on the solvent used and environmental conditions. An experimental approach should be employed to accurately determine its solubility behavior in various media.

Interesting facts

Interesting Facts about N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide

N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide is a fascinating compound with a variety of intriguing aspects worth exploring. Here are some key highlights:

  • Synthetic Versatility: This compound is a member of the acetamide class, which is renowned for its diverse synthetic applications. Compounds like this are often used as intermediates in the synthesis of pharmaceuticals and agrochemicals.
  • Unique Structure: The structure features both a dimethylphenyl group and a hexahydropyrrolizin moiety. This combination allows for unique interactions in biological systems, contributing to its potential therapeutic effects.
  • Biological Significance: Compounds with similar structures have shown activity in various biological systems, including anti-inflammatory and analgesic activities. This piques interest in its potential for drug development.
  • Investigative Research: As a relatively novel compound, ongoing research is likely focused on understanding its mechanisms of action and its role in developing new medicinal therapies.
  • Structure-Activity Relationship (SAR): Studying how changes in the structure affect biological activity is crucial in medicinal chemistry, and this compound provides a rich avenue for exploration in SAR studies.

To sum it up, N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide is not just a simple compound; it is a potential gateway to new discoveries in pharmaceuticals, making it an exciting subject for chemists and researchers alike.

Synonyms
Pilsicainide
88069-67-4
Pilzicainide
Pilsicainida
Pilsicainide [INN]
Pilsicainidum
Pilsicainida [INN-Spanish]
N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
Pilsicainidum [INN-Latin]
N-(2,6-Dimethylphenyl)-2-(hexahydro-1H-pyrrolizin-7a-yl)acetamide
UNII-AV0X7V6CSE
AV0X7V6CSE
N-(2,6-Dimethylphenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide
Pilsicainide (INN)
DTXSID1046639
SUN-1165
Tetrahydro-1H-pyrrolizine-7a(5H)-aceto-2',6'-xylidide
PILSICAINIDE [MI]
PILSICAINIDE [WHO-DD]
DTXCID9026639
CHEBI:135127
Tox21 112458
NCGC00167454-01
1H-Pyrrolizine-7a(5H)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-
Pilsicainidum (INN-Latin)
Pilsicainida (INN-Spanish)
SUN 1165 (TN)
CAS-88069-67-4
SCHEMBL142244
CHEMBL163238
BCP13541
NDA06967
Tox21_112458
BDBM50413638
AKOS015907410
Tox21_112458_1
DB12712
NCGC00167454-02
AS-13229
HY-133715
CS-0129948
NS00072619
D08377
SUN 1165; SUN-1165; SUN1165
Q7194521
BRD-K83245588-001-01-4