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6-Nitroguaiacol

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Identification
Molecular formula
C7H7NO4
CAS number
552-32-9
IUPAC name
N-(2,5-dihydroxyphenyl)-N-methyl-nitrous amide
State
State

At room temperature, 6-Nitroguaiacol is in a solid state. It is relatively stable under ordinary conditions of use and storage, but care should be taken to avoid exposure to excessive heat or humidity, which could cause it to degrade or react with other chemicals.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
317.00
Boiling point (Kelvin)
590.15
General information
Molecular weight
168.14g/mol
Molar mass
168.1380g/mol
Density
1.7030g/cm3
Appearence

6-Nitroguaiacol typically appears as a yellow crystalline solid. It may also come in powder form and has a characteristic aromatic odor that is typical of nitrophenol derivatives. Under UV light, especially shortwave, it may exhibit some fluorescence.

Comment on solubility

Solubility of N-(2,5-dihydroxyphenyl)-N-methyl-nitrous amide (C7H7NO4)

N-(2,5-dihydroxyphenyl)-N-methyl-nitrous amide, with the formula C7H7NO4, exhibits unique solubility characteristics due to its molecular structure. This compound features multiple hydroxyl groups which can significantly influence its solubility in various solvents.

Key points regarding its solubility include:

  • Water Solubility: The presence of hydroxyl (-OH) groups suggests that C7H7NO4 may be soluble in polar solvents like water, promoting hydrogen bonding.
  • Organic Solvents: It may also find solubility in some organic solvents, particularly those that are polar, due to its ability to interact with solvent molecules.
  • Temperature Dependence: The solubility can vary with temperature, often increasing at elevated temperatures for many organic compounds.

The solubility behavior of this compound can be complex; hence, it is essential to consider experimental data for practical applications. As a rule of thumb, “like dissolves like” is a useful principle, emphasizing the importance of solvent polarity when predicting solubility. Understanding these dynamics is crucial for its utilization in chemical processes or formulations.

Interesting facts

Interesting Facts about N-(2,5-dihydroxyphenyl)-N-methyl-nitrous amide

N-(2,5-dihydroxyphenyl)-N-methyl-nitrous amide, commonly known within chemical circles for its unique structure and potential applications, offers a fascinating glimpse into the world of organic compounds. Here are some key insights:

  • Chemical Structure: This compound features a nitrous amide group, which plays a vital role in its reactivity and interaction with biological systems. The presence of the 2,5-dihydroxyphenyl moiety indicates a capability for hydrogen bonding, which could enhance its solubility in various solvents.
  • Biochemical Role: Researchers have been investigating the potential biological activities of nitrous amides. Compounds like this are often explored for their role as pharmacophore groups in drug development, particularly in targeting specific receptors within the body.
  • Synthesis Methods: The methods for synthesizing such compounds often involve intricate organic reactions, including nitrosation and a series of condensation reactions. Understanding these synthetic pathways helps chemists innovate more efficient production methods.
  • Potential Applications: This compound has shown promise in various fields, including:
    1. Medicinal Chemistry: Exploring its potential as an antimicrobial or anti-inflammatory agent.
    2. Material Science: Investigating its use in creating new materials with desirable properties.
    3. Analytical Chemistry: Utilizing its unique properties for more effective detection methods in biochemical assays.

Furthermore, the study of compounds like N-(2,5-dihydroxyphenyl)-N-methyl-nitrous amide exemplifies the connection between structure and function. As researchers continue to explore this compound, we can look forward to uncovering new and exciting applications that could impact various scientific fields.

As famed chemist Marie Curie once said, “One never notices what has been done; one can only see what remains to be done.” The journey of understanding and leveraging compounds like this is a testament to the ever-evolving nature of chemistry.

Synonyms
dephostatin
151606-30-3
1,4-Benzenediol, 2-(methylnitrosoamino)-
2-(Methylnitrosoamino)-1,4-benzenediol
N-(2,5-dihydroxyphenyl)-N-methylnitrous amide
2-[(hydroxyamino)-methylamino]cyclohexa-2,5-diene-1,4-dione
Lopac-D-8065
Lopac0_000403
CHEMBL269733
SCHEMBL3893046
SCHEMBL12305062
DTXSID30934304
CHEBI:202847
HMS3261A08
2-(N-methyl-N-nitroso)hydroquinone
Tox21_500403
HSCI1_000163
AKOS006271953
CCG-204496
LP00403
SDCCGSBI-0050389.P002
1,4-Dihydroxy-N-methyl-N-nitrosoaniline
NCGC00015372-01
NCGC00015372-02
NCGC00015372-03
NCGC00015372-04
NCGC00093830-01
NCGC00093830-02
NCGC00261088-01
1,4-Benzenediol,2-(methylnitrosoamino)-
D8065
EU-0100403
D 8065
SR-01000075834
SR-01000075834-1
2-(2-Hydroxy-1-methylhydrazinyl)cyclohexa-2,5-diene-1,4-dione