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Acetanisole

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Identification
Molecular formula
C9H11NO2
CAS number
544-67-2
IUPAC name
N-(2-methoxyphenyl)acetamide
State
State

At room temperature, N-(2-methoxyphenyl)acetamide exists in a solid crystalline state. It is relatively stable under standard conditions.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.15
General information
Molecular weight
151.17g/mol
Molar mass
151.1650g/mol
Density
1.0344g/cm3
Appearence

N-(2-methoxyphenyl)acetamide is a crystalline solid with a white to off-white color. It may also occur as slightly beige crystals, depending on purity and the presence of impurities.

Comment on solubility

Solubility of N-(2-methoxyphenyl)acetamide

N-(2-methoxyphenyl)acetamide, also known as N-(2-methoxyphenyl)ethanamide, exhibits notable solubility characteristics that are crucial to its applications in various fields. Below are some key points regarding its solubility:

  • Solvent Compatibility: This compound is generally soluble in organic solvents. Commonly used solvents include:
    • Ethanol
    • DMSO (Dimethyl sulfoxide)
    • Acetone
  • Water Solubility: The solubility of N-(2-methoxyphenyl)acetamide in water is limited. This could be attributed to its hydrophobic aromatic structure, which tends to favor interactions with non-polar environments.
  • Temperature Influence: Like many organic compounds, solubility can be influenced by temperature; an increase in temperature may enhance its solubility in organic solvents.
  • pH Dependence: The solubility of this compound can also vary with changes in pH, impacting its ionization state, which in turn can affect its solubility in aqueous solutions.

In summary, while N-(2-methoxyphenyl)acetamide demonstrates favorable solubility in organic solvents, its limited solubility in water may present challenges for certain applications. Understanding these solubility behaviors is key to effectively utilizing this compound in research and industry.

Interesting facts

Interesting Facts about N-(2-Methoxyphenyl)acetamide

N-(2-Methoxyphenyl)acetamide is a fascinating compound that showcases the intersection of organic chemistry and medicinal applications. Here are some compelling insights:

  • Functional Group Diversity: This compound features an amide functional group, which is known for its importance in both biological systems and synthetic chemistry. Amides are critical in the formation of proteins and play essential roles in various biochemical processes.
  • Pharmacological Potential: Compounds featuring the methoxy group are often investigated for their pharmaceutical properties. Research suggests that N-(2-methoxyphenyl)acetamide may exhibit anti-inflammatory and analgesic effects, making it a potential candidate for drug development.
  • Substituent Effects: The placement of the methoxy group on the aromatic ring can influence the compound's reactivity and biological activity. This is a prime example of how small structural modifications can lead to significant changes in a compound's properties.
  • Research Relevance: This compound serves as an intriguing subject for synthetic chemists, particularly when studying methodologies for the preparation of cyclic compounds or exploring regioselectivity in aromatic substitutions.
  • Literature Insights: Various studies highlight the roles of similar compounds in agrochemical development and materials science, demonstrating the broad applicability of the acetyl and methoxy functional groups.

In summary, N-(2-Methoxyphenyl)acetamide is not just another organic molecule; it symbolizes the rich tapestry of research possibilities in chemistry. As we delve deeper into its characteristics and potential uses, we can appreciate the intricate details that make this compound noteworthy in both scientific and practical contexts.

Synonyms
N-(2-Methoxyphenyl)acetamide
93-26-5
o-ACETANISIDIDE
o-Methoxyacetanilide
o-Acetanisidine
2-Methoxyacetanilide
2'-Methoxyacetanilide
Acetamide, N-(2-methoxyphenyl)-
Acetanilide, 2'-methoxy-
NSC 4004
EINECS 202-233-5
LPJ345W2VY
BRN 2091808
N-Acetyl-o-anisidine
AI3-00799
NSC-4004
MFCD00026117
DTXSID0052623
2-ACETAMIDOANISOLE
oAcetanisidide
oAcetanisidine
N-(2-Methoxy-phenyl)-acetamide
Aceto-o-anisidine
oMethoxyacetanilide
NSC4004
2'Methoxyacetanilide
N-(2-METHOXYPHENYL) ACETAMIDE
N-acetyl-2-anisidine
2-(Acetylamino)anisole
Acetanilide, 2'methoxy
UNII-LPJ345W2VY
Cambridge id 5137141
WLN: 1VMR BO1
Acetamide, N(2methoxyphenyl)
MLS000105047
SCHEMBL171580
N-(2-methoxyphenyl)-acetamide
N-ACETYL-ORTHO-ANISIDINE
CHEMBL1880779
DTXCID4031196
N-(2-Methoxyphenyl)acetamide #
CHEBI:143106
HMS1577L04
HMS2339K05
AAA09326
N-(2-Methoxyphenyl)acetamide, 95%
STL169049
AKOS000498231
SDCCGMLS-0033745.P002
AS-59474
SMR000054976
SY107302
A0018
CS-0313101
NS00039539
o-Acetanisidide;N-(2-Methoxyphenyl)acetamide
D88200
AE-641/00783050
Q63392790
Z27797377
InChI=1/C9H11NO2/c1-7(11)10-8-5-3-4-6-9(8)12-2/h3-6H,1-2H3,(H,10,11
202-233-5