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Baclofen

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Identification
Molecular formula
C10H12ClNO2
CAS number
1134-47-0
IUPAC name
N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide
State
State

At room temperature, Baclofen is in a solid state. It typically exists as a powder that is soluble in solvents like alcohol and slightly soluble in water. It is often used in medicinal contexts and generally found in this solid form for pharmaceutical preparations.

Melting point (Celsius)
206.00
Melting point (Kelvin)
479.15
Boiling point (Celsius)
451.30
Boiling point (Kelvin)
724.45
General information
Molecular weight
213.25g/mol
Molar mass
213.2480g/mol
Density
1.0465g/cm3
Appearence

Baclofen appears as a white to off-white crystalline powder. It is odorless and has a bitter taste. In its crystalline form, the compound tends to be relatively stable.

Comment on solubility

Solubility of N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide

The solubility of N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide (C10H12ClNO2) can be influenced by several factors, including its molecular structure, polarity, and the solvent used. Here are some key points regarding its solubility:

  • Polar and Nonpolar Characteristics: The presence of the hydroxyl (-OH) group contributes to the *polar* nature of the compound, while the tetradecanamide tail introduces a *nonpolar* characteristic.
  • Solvent Compatibility: Generally, compounds with significant polar groups like -OH are more soluble in *polar solvents* such as water. However, the long hydrophobic hydrocarbon chain may limit its solubility.
  • Degree of Solubility: It is likely that N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide exhibits *moderate* solubility in organic solvents such as ethanol or methanol, which can interact with its polar sites.
  • Temperature Dependency: Like many organic compounds, its solubility may increase with *temperature*, making higher temperatures beneficial for dissolving the compound in a given solvent.

In summary, while N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide may have some solubility in polar solvents, its hydrophobic characteristics could limit its overall solubility profile. This dual nature creates a complex solubility behavior that could be further explored through experimental examination.

Interesting facts

Interesting Facts about N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide

N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide, often referred to in scientific literature by its systematic name, is a fascinating compound with diverse applications and properties that make it a subject of study in various fields of science.

Key Characteristics

  • Unique Structure: This compound features a unique structure characterized by a long alkyl chain and a phenyl group, which plays a crucial role in its physical and chemical behavior.
  • Biological Significance: It has been investigated for its potential bioactivity, including its role in certain biochemical pathways, which could have implications in pharmacology.
  • Amide Linkage: The amide functional group can serve as a key feature in drug design, affecting the polarity and solubility of the molecule.

Applications

  • Cosmetic Industry: With its characteristic properties, this compound may be utilized as an emollient or thickening agent in cosmetic formulations.
  • Pharmaceuticals: Its potential therapeutic applications are still being explored, making it an interesting candidate for drug development.
  • Materials Science: The characteristics of this compound can be leveraged in creating novel materials with specific properties for industrial applications.

As noted by many researchers, "the interplay of the alkyl chain and the phenyl group in such compounds often leads to unexpected physical properties." This maxim reinforces the **importance of molecular design** in developing compounds with tailored functionalities.

In summary, N-(2-hydroxy-1-methyl-2-phenyl-ethyl)tetradecanamide showcases the intricate balance between structure and function, making it a compelling subject for continued exploration in chemistry and applied sciences.

Synonyms
n-(1-hydroxy-1-phenylpropan-2-yl)tetradecanamide
2-(N-Myristoylamino)-1-phenyl-1-propanol
919770-84-6
SCHEMBL360960
DTXSID70274392
DB-216547