Bicalutamide | Solubility of Things

Identification

Molecular formula

C₁₈H₁₄F₄N₂O₄S

CAS number

90357-06-5

IUPAC name

N-(2-aminophenyl)-3-[4-(benzenesulfonamido)phenyl]prop-2-enamide

State

At room temperature, Bicalutamide is typically found in a solid state as a crystalline powder.

Melting point (Celsius)

192.50

Melting point (Kelvin)

465.70

Boiling point (Celsius)

586.50

Boiling point (Kelvin)

859.70

General information

Molecular weight

430.38g/mol

Molar mass

430.3750g/mol

Density

1.2840g/cm³

Appearence

Bicalutamide appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-(2-aminophenyl)-3-[4-(benzenesulfonamido)phenyl]prop-2-enamide

The solubility of the compound N-(2-aminophenyl)-3-[4-(benzenesulfonamido)phenyl]prop-2-enamide (C₁₈H₁₄F₄N₂O₄S) presents a complex scenario due to its multifaceted structure. Several factors influence the solubility characteristics of this compound:

Polarity: The presence of functional groups such as the sulfonamide and amine contributes to the overall polarity of the molecule, potentially increasing its solubility in polar solvents.
Solvent Interaction: Solubility may vary significantly between different solvents. For example, it is likely to be more soluble in aqueous solutions compared to organic solvents due to hydrogen bonding interactions.
Temperature effect: An increase in temperature generally enhances solubility, as it may facilitate better interactions between solute and solvent molecules.
pH dependence: The ionization of the amine group can be influenced by pH, which may alter the solubility behavior in different environmental conditions.

In summary, the solubility of N-(2-aminophenyl)-3-[4-(benzenesulfonamido)phenyl]prop-2-enamide is nuanced, influenced by factors such as polarity, solvent choice, temperature, and pH. This compound serves as a prime example of the interplay between molecular structure and solubility, emphasizing the need for tailored approaches when predicting and testing solubility in laboratory settings.

Interesting facts

Interesting Facts about N-(2-aminophenyl)-3-[4-(benzenesulfonamido)phenyl]prop-2-enamide

N-(2-aminophenyl)-3-[4-(benzenesulfonamido)phenyl]prop-2-enamide is a fascinating organic compound that boasts a variety of intriguing properties and potential applications. Here are some noteworthy aspects:

Medicinal Chemistry: This compound is of significant interest in the field of medicinal chemistry due to its potential pharmacological activities. Its structure may enable interactions with various biological targets, which could lead to the development of new therapeutic agents.
Unique Functional Groups: The presence of both an amine and a sulfonamide in its structure imparts unique reactivity and functional characteristics. This combination is often associated with compounds that exhibit anti-inflammatory and antimicrobial properties.
Research Interest: Scientists are continually exploring the implications of this compound in drug design. Studies are being conducted to evaluate its efficacy and safety as a potential treatment for various diseases.
Diversity in Applications: Beyond medicinal applications, compounds containing amido and sulfonamide functionalities can play critical roles in agrochemicals, dyes, and polymer science, showcasing their versatility in different fields.
Structural Complexity: The compound's intricate design, including an extended aromatic system, suggests possible interactions with protein targets, enhancing its potential as a lead compound for further exploration.

In conclusion, N-(2-aminophenyl)-3-[4-(benzenesulfonamido)phenyl]prop-2-enamide is more than just a chemical entity; it represents the intersection of chemistry and pharmacology, embodying the promise of innovative therapeutic solutions as research progresses. Its unique structural attributes pave the way for deeper investigations into its capabilities and applications.