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5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT)

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Identification
Molecular formula
C13H18N2O1
CAS number
1019-45-0
IUPAC name
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide
State
State

At room temperature, 5-MeO-DMT is typically in a solid state. It is stable under normal conditions but can degrade if exposed to light or moisture over time.

Melting point (Celsius)
69.50
Melting point (Kelvin)
342.65
Boiling point (Celsius)
310.80
Boiling point (Kelvin)
583.95
General information
Molecular weight
218.30g/mol
Molar mass
218.3150g/mol
Density
1.1440g/cm3
Appearence

5-MeO-DMT is typically a white or off-white crystalline powder that may appear fluffy or fine in texture. It is often found in pure form but can also sometimes appear as a shiny, crystalline solid.

Comment on solubility

Solubility of N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide

N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide (C13H18N2O1) displays unique solubility characteristics that can be influenced by several factors. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of the methoxy group and amide functional group suggests that the compound may exhibit moderate to good solubility in polar solvents such as water.
  • Solvent-Specific Behavior: It is likely to be soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) due to its hydrophobic cyclopropane ring and indole structure.
  • Temperature Dependency: As with many organic compounds, solubility may increase with temperature, allowing for a greater dissolution in solution.
  • pH Influence: The solubility might also be affected by pH variations, especially if the compound undergoes protonation or deprotonation.

In summary, while empirical data could provide more definitive insights, it is reasonable to conclude that N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide features varying solubility in different solvents, influenced by its chemical structure and environmental conditions.

Interesting facts

Interesting Facts About N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide

N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide is a fascinating compound that lies at the intersection of organic chemistry and medicinal research. Here are some engaging facts about this compound:

  • Structural Complexity: This compound features a unique cyclopropane ring, which is a three-membered carbon structure. Cyclopropane rings are known for their strain but can yield interesting reactivity properties.
  • Indole Derivative: The presence of the indole structure in its formula suggests potential bioactivity. Indoles are often found in natural products and have been linked to a variety of pharmacological effects.
  • Neuroscience Applications: Due to its indole moiety, this compound may interact with neurotransmitter systems, potentially serving as a lead compound for treatments in neuropharmacology and psychiatric disorders.
  • Molecular Interactions: The methoxy group could enhance lipophilicity, improving the membrane permeability of the compound, which is a crucial factor for drug design.
  • Potential for Analog Synthesis: Scientists may explore variations of this compound to design new drugs with improved efficacy or reduced side effects, highlighting the importance of structure-activity relationship (SAR) studies.
  • Research Significance: Compounds like this are often subjects of ongoing research to understand how subtle changes in molecular structure can lead to significant variations in biological activity.

In summary, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide showcases the intricate dance of molecular architecture, reactivity, and biological potential that is often the core of medicinal chemistry. As researchers continue to delve into such compounds, the hope is to unlock new therapeutic avenues and enhance our understanding of chemical interactions in biological systems.

Synonyms
139564-01-5
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]cyclopropanecarboxamide
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)cyclopropanecarboxamide
5-methoxy-n-cyclopropanoyltryptamine
CHEMBL37549
Cyclopropanecarboxamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-
cpmt
HSOHROOUHRUSJR-UHFFFAOYSA-N
Oprea1_112586
Oprea1_219984
CBDivE_000390
SCHEMBL4759323
N-[2-(5-Methoxyindol-3-yl)ethyl]-cyclopropylcarboxamide
DTXSID10274391
HMS1613L03
N-cyclopropanoyl-5-methoxytryptamine
BDBM50230659
STK055251
AKOS000623667
CCG-112224
NCGC00163258-01
PD075992
AI-981/09942044
L008209