Abamectin | Solubility of Things

Identification

Molecular formula

C₄₈H₇₂O₁₄

CAS number

71751-41-2

IUPAC name

N-[2-[5-[3-acetamido-6-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-6-[[17-(1,5-dimethyl-3-oxo-hex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-tetrahydropyran-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]acetamide

State

At room temperature, abamectin is typically in a solid state, appearing as crystalline powder. This solid form is common for this compound under standard laboratory and storage conditions.

Melting point (Celsius)

150.00

Melting point (Kelvin)

423.15

Boiling point (Celsius)

183.00

Boiling point (Kelvin)

456.15

General information

Molecular weight

872.09g/mol

Molar mass

872.0920g/mol

Density

1.1605g/cm³

Appearence

Abamectin is a white to yellowish crystalline powder. It is solid at room temperature and may be faintly colored, giving it a slightly off-white appearance based on purity and manufacturing conditions.

Comment on solubility

Solubility of N-[2-[5-[3-acetamido-6-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-6-[[17-(1,5-dimethyl-3-oxo-hex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-tetrahydropyran-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]acetamide

The solubility of this complex compound, with the chemical formula C₄₈H₇₂O₁₄, is influenced by several factors due to its unique structure. Understanding these aspects can shed light on its behavior in various solvents:

Polarity: The presence of multiple hydroxyl (-OH) groups makes the compound more polar, which typically enhances its solubility in polar solvents such as water.
Hydrogen Bonding: The numerous hydroxyl functionalities can engage in hydrogen bonding with solvent molecules, potentially increasing solubility.
Hydrophobic Regions: The compound's structure also includes hydrophobic groups which may lead to reduced solubility in highly polar solvents, thereby suggesting a complex interplay between hydrophilic and hydrophobic characteristics.
Temperature Dependence: Like many organic compounds, solubility may vary with temperature—typically increasing at elevated temperatures.

In summary, while the presence of multiple polar functional groups generally supports solubility in polar solvents, the overall structural complexity and hydrophobic segments might hinder complete solubility under all conditions. Thus, specific experimental validation in target solvents is recommended to determine the effective solubility of this compound.

Interesting facts

Interesting Facts About N-[2-[5-[3-Acetamido-6-[4,5-Dihydroxy-6-(Hydroxymethyl)-3-[3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydropyran-2-Yl]Oxy-Tetrahydropyran-2-Yl]Oxy-4,5-Dihydroxy-Tetrahydropyran-2-Yl]Oxy-6-[[17-(1,5-Dimethyl-3-Oxo-Hex-4-Enyl)-4,4,10,13,14-Pentamethyl-2,3,5,6,7,8,12,15,16,17-Decahydro-1H-Cyclopenta[a]Phenanthren-3-Yl]Oxy]-4-Hydroxy-Tetrahydropyran-3-Yl]Acetamide

N-[2-[5-[3-acetamido-6-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-6-[[17-(1,5-dimethyl-3-oxo-hex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-tetrahydropyran-3-yl]acetamide, often referred to by its shorthand names among researchers, is a complex organic compound characterized by a rich molecular architecture. Here are some prominent aspects to consider:

Intricate Structure: The compound boasts an intricate structure comprised of multiple hydroxyl and tetrahydropyran groups, making it a subject of interest in carbohydrate chemistry.
Biological Significance: Its unique arrangement allows potential interactions with biological macromolecules, suggesting roles in medicinal and biochemical applications.
Synthetic Challenges: The complex synthesis pathway for this compound reflects both the beauty and difficulty encountered in organic chemistry today, often necessitating advanced techniques and methodologies.
Therapeutic Potential: Researchers are investigating its properties for therapeutic applications, particularly in areas related to anti-inflammatory and antioxidant activities due to the presence of hydroxyl groups which are known for such actions.
Interdisciplinary Interest: Beyond organic synthesis, the compound intersects with fields such as pharmacology, biochemistry, and materials science.
Research Frontier: Scientists continue to explore various derivatives of this molecule to enhance its efficacy and reduce any potential side effects.

In summary, this compound represents not just a molecular composition, but a profound potential to contribute to various fields of study. As noted by chemists, "the journey through the complexity of its structure often leads to remarkable discoveries."