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Cimetidine

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Identification
Molecular formula
C10H16N6O4
CAS number
51481-61-9
IUPAC name
N-[2-[[2-[2-(dimethylamino)ethylcarbamoyl]-1-methyl-imidazol-4-yl]carbamoyl]-1-methyl-imidazol-4-yl]-4-formamido-1-methyl-imidazole-2-carboxamide
State
State

At room temperature, cimetidine is in a stable solid form. It is typically encountered as tablets or capsules in pharmaceutical settings, being an essential medication for managing certain stomach disorders.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
618.15
Boiling point (Kelvin)
891.30
General information
Molecular weight
252.34g/mol
Molar mass
252.3440g/mol
Density
1.1800g/cm3
Appearence

Cimetidine is typically found as a crystalline powder. It can appear as a white to pale yellow solid. Due to its nature, it may exhibit slight hygroscopic properties.

Comment on solubility

Solubility of N-[2-[[2-[2-(dimethylamino)ethylcarbamoyl]-1-methyl-imidazol-4-yl]carbamoyl]-1-methyl-imidazol-4-yl]-4-formamido-1-methyl-imidazole-2-carboxamide (C10H16N6O4)

The solubility of this complex compound is quite intriguing due to its intricate structure and functional groups. Here are some essential points regarding its solubility:

  • Polarity: The presence of multiple amide and imidazole groups suggests a high degree of polarity, which typically enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds, due to the presence of nitrogen and oxygen atoms, likely contributes to favorable interactions with solvent molecules, promoting solubility.
  • Solvent Interaction: It is expected that the compound may exhibit solubility in various aqueous and organic solvents, although the specific solvent system may significantly affect the degree of solubility.
  • Concentration Effects: At higher concentrations, solubility may be influenced by its potential to aggregate or precipitate, a common phenomenon in biologically relevant chemicals.

In conclusion, while definitive solubility data might be scarce, the structural characteristics of C10H16N6O4 strongly suggest it is soluble in polar environments. This underlines the importance of empirical testing to determine precise solubility metrics under varying conditions.

Interesting facts

Interesting Facts about N-[2-[[2-[2-(dimethylamino)ethylcarbamoyl]-1-methyl-imidazol-4-yl]carbamoyl]-1-methyl-imidazol-4-yl]-4-formamido-1-methyl-imidazole-2-carboxamide

This complex compound belongs to a class of organic compounds known for their diverse applications in biochemistry and medicinal chemistry. It showcases the fascinating structure of imidazoles, which are five-membered heterocycles containing two nitrogen atoms.

Here are some interesting points regarding this compound:

  • Biological Significance: Imidazole derivatives are known to exhibit a range of biological activities, making them important in drug design and development.
  • Versatile Applications: This compound may serve as a building block for synthesizing pharmaceuticals, potentially paving the way for novel therapeutics.
  • Structure-Activity Relationship: The intricate arrangement of functional groups within this compound allows scientists to explore how structural changes can influence biological activity and potency.
  • Dimethylamino Group: The presence of the dimethylamino group suggests potential for enhanced lipophilicity, which can impact drug absorption and distribution in biological systems.

As a chemist or a student, delving into the phonetics of nomenclature can be a learning adventure. This name describes a compound with multiple imidazolyl groups, highlighting the integration of various functional groups that can lead to unique chemical properties. It epitomizes the complexity of organic synthesis and the creativity involved in the design of molecules for specific purposes.

In summary, this compound not only represents the genius of organic chemistry but also underscores the importance of structure in determining function, reminding us of the ever-evolving relationship between chemistry and biomedicine.

Synonyms
147056-66-4
N-(2-(((2-(Dimethylamino)ethyl)amino)carbonyl)-1-methyl-1H-imidazol-4-yl)-4-(((4-(formylamino)-1-methyl-1H-imidazol-2-yl)carbonyl)amino)-1-methyl-1H-imidazole-2-carboxamide
CHEMBL167216
DTXSID40933020
[2-({2-[(2-{[2-(Dimethylamino)ethyl]carbamoyl}-1-methyl-1H-imidazol-4-yl)carbamoyl]-1-methyl-1H-imidazol-4-yl}carbamoyl)-1-methyl-1H-imidazol-4-yl]methanimidic acid