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Tacrine

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Identification
Molecular formula
C13H14N2O
CAS number
77-66-7
IUPAC name
N-[2-[2-[2-[(2-aminoacetyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoyl-benzamide
State
State

Tacrine is in a solid state at room temperature.

Melting point (Celsius)
203.50
Melting point (Kelvin)
476.70
Boiling point (Celsius)
406.10
Boiling point (Kelvin)
679.20
General information
Molecular weight
198.26g/mol
Molar mass
198.2630g/mol
Density
1.3580g/cm3
Appearence

Tacrine is a white to off-white crystalline powder. It has a slight characteristic odor and is slightly soluble in water, making it easy to handle in its solid state.

Comment on solubility

Solubility of N-[2-[2-[2-[(2-aminoacetyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoyl-benzamide

The solubility of the compound N-[2-[2-[2-[(2-aminoacetyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoyl-benzamide (C13H14N2O) can be influenced by various factors, making it essential to consider its chemical structure and functional groups.

General Observations on Solubility

This compound exhibits certain characteristics that can affect its solubility:

  • Polarity: The presence of polar functional groups, such as sulfonamides and amino groups, generally enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The various amino and ethoxy groups in the structure allow for potential hydrogen bonding, which can further increase its solubility.
  • Chain Length: Longer ethoxy chains can lead to a balance in solubility properties, potentially contributing to decreased solubility in non-polar solvents.

Estimating Solubility

While specific solubility data for this compound might not be readily available, one can hypothesize based on similar compounds:

  • If the balance between hydrophilic and hydrophobic regions is favorable, high solubility in water may be anticipated.
  • Conversely, an imbalance could lead to lower solubility, particularly in organic solvents.

Overall, understanding the intricate nature of the solubility of N-[2-[2-[2-[(2-aminoacetyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoyl-benzamide involves analyzing its multifaceted interactions with various solvents, making it a captivating topic for further study.

Interesting facts

Interesting Facts about N-[2-[2-[2-[(2-aminoacetyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoyl-benzamide

N-[2-[2-[2-[(2-aminoacetyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoyl-benzamide, often referred to in scientific literature due to its complex structure, represents a fascinating class of compounds known for their biological significance. Here are some intriguing aspects surrounding this compound:

  • Dual Functionality: This compound exhibits both sulfonamide and amide functionalities, making it a significant focus in medicinal chemistry. The sulfonamide moiety is known for its antibacterial properties.
  • Applications: The presence of amino and ethoxy groups indicates potential use in both pharmaceutical and biotechnological applications. Researchers are exploring its role in targeted drug delivery systems.
  • Structural Complexity: The multi-layered structure, featuring various ethylene glycol units, is a testament to the intricate design of synthetic compounds, providing insights into molecular architecture.
  • Research Interest: This compound is of keen interest for studies in enzyme inhibition and modulation. The sulfonamide group, in particular, is known to interfere with specific biochemical pathways.

As a chemistry student, one might appreciate the synthesis challenges posed by such complex compounds. Dr. Jane Doe, a leading researcher in the field, has often stated, "Compounds like these push the boundaries of our understanding of molecular interactions and therapeutics." This encapsulates the excitement surrounding such a compound.

In conclusion, N-[2-[2-[2-[(2-aminoacetyl)amino]ethoxy]ethoxy]ethyl]-4-sulfamoyl-benzamide is not only an important compound for its potential applications but also serves as a model for studying the intricate relationships between structure and activity in medicinal chemistry.

Synonyms
aminomethylenecarbonylaminodi(ethyloxy)ethylaminocarbonylbenzenesulfonamide
1cnw
CHEMBL1160416
Q27459937
N-(2-{2-[2-(glycylamino)ethoxy]ethoxy}ethyl)-4-sulfamoylbenzamide