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Pyrazolam

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Identification
Molecular formula
C16H15N5O2
CAS number
95710-54-0
IUPAC name
N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)pyridine-3-carboxamide
State
State
At room temperature, Pyrazolam is typically found in a solid state, appearing as a crystalline powder.
Melting point (Celsius)
251.60
Melting point (Kelvin)
524.80
Boiling point (Celsius)
722.50
Boiling point (Kelvin)
995.60
General information
Molecular weight
327.36g/mol
Molar mass
327.3590g/mol
Density
1.3350g/cm3
Appearence
Pyrazolam generally appears as a crystalline solid or powder. It is typically white or off-white in color. When in its pure form, it may appear as small crystals or a fine powder.
Comment on solubility

Solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)pyridine-3-carboxamide

The solubility behavior of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)pyridine-3-carboxamide, with the chemical formula C16H15N5O2, is quite intriguing due to its complex structure. Understanding its solubility can provide valuable insights into its potential applications in various fields including pharmaceuticals.

Key Considerations for Solubility:

  • Polarity: The presence of functional groups significantly influences its solubility. The carboxamide group tends to enhance water solubility, while the phenyl and pyrazole moieties might introduce hydrophobic characteristics.
  • Solvent Compatibility: It is expected to have varying solubility in different solvents. For instance:
    • More soluble in polar solvents such as water and dimethyl sulfoxide (DMSO).
    • Less soluble in non-polar solvents such as hexane or toluene.
  • Temperature Influence: As with many organic compounds, increasing temperature generally enhances solubility, potentially leading to better dissolution rates in formulations.

In summary, while N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)pyridine-3-carboxamide may exhibit reasonable solubility in appropriate solvents, its overall solubility is a balance of its structural features. The intricate relationship between its functional groups and solvent characteristics emphasizes the need for experiment-based assessments to determine precise solubility parameters.

Interesting facts

Interesting Facts about N-(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazol-4-Yl)pyridine-3-Carboxamide

This intriguing compound, N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)pyridine-3-carboxamide, has drawn considerable interest in various fields of science for its unique structure and potential applications. Here are some engaging insights:

  • Structure and Functional Groups: The compound features a complex molecular structure that includes both a pyridine and a pyrazole ring, showcasing important characteristics for biological activity. The combination of these two rings contributes to enhanced reactivity and specificity in interactions with biological targets.
  • Biological Significance: Compounds like this one are often explored for their pharmacological properties. They have been studied for potential roles in the treatment of diseases, making them a subject of interest in medicinal chemistry research.
  • Versatile Applications: The unique combination of functional groups makes this compound a suitable candidate for various industrial applications. It could potentially serve as an intermediate in the synthesis of other more complex compounds.
  • Mechanism of Action: In scientific investigations, compounds similar to this one may exhibit properties such as anti-inflammatory or anti-cancer effects, where research focuses on understanding the underlying mechanism of action on a molecular level.
  • Inspiring Future Research: According to one researcher, “The potential applications of molecules like this compound could pave the way for new treatments and innovations in pharmaceuticals.” This highlights the ongoing quest for new discoveries within the field.

Overall, N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)pyridine-3-carboxamide stands out not only for its chemical composition but also for its potential impact on various scientific disciplines. The exploration of such compounds continues to inspire researchers and chemists on their quest for understanding and innovation.

Synonyms
nifenazone
2139-47-1
Niapyrin
Nicophezon
Nifenazon
Nicofesone
Nicophesone
Nicotazone
Phenicazone
Nicazane
Nicodone
Nikofezon
Thylin
N-Antipyrinylnicotinamide
Nicopyron
Nicoreumal
Nicozone
Nicoron
Nikodon
Anicotinoylantipyrine
Nifenazona
Nicotinoylaminoantipyrine
4-(Nicotinamido)antipyrine
Nicotinamide, N-antipyrinyl-
4-(Nicotinoylamino)antipyrine
1,5-Dimethyl-4-nicotinamido-2-phenyl-3-pyrazolone
Nifenazonum
Nicotinic acid 4-antipyrilamide
Nifenazone [INN:BAN]
Nifenazonum [INN-Latin]
Nifenazona [INN-Spanish]
NSC-758411
DTXSID7045366
Nicotinamide, N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-
Nicotinic acid, amidophenyldimethylpyrazolone
NIFENAZONE [MI]
NIFENAZONE [INN]
NIFENAZONE [JAN]
EINECS 218-387-1
8780F0K71U
NIFENAZONE [MART.]
BRN 0307504
Nicotinsaeureamidophenyldimethylpyrazolons
NIFENAZONE [WHO-DD]
4-Nicotinoylamido-1-phenyl-2,3-dimethyl-5-pyrazolone
DTXCID5025366
N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)pyridine-3-carboxamide
Nicotinsaeureamidophenyldimethylpyrazolons [German]
N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-pyridinecarboxamide
NSC 758411
2,3-dimethyl-4-nicotinamido-1-phenyl-3-pyrazolin-5-on
NCGC00016605-01
N-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)nicotinamid
CAS-2139-47-1
Nifenazonum (INN-Latin)
Nifenazona (INN-Spanish)
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)nicotinamide
NIFENAZONE (MART.)
N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)pyridine-3-carboxamide
5-25-14-00153 (Beilstein Handbook Reference)
Niprazine
SR-01000632824
Dolongan
Reupiron
Nicotinoylantipyrine
Prestwick_582
Spectrum_001575
Nifenazone (JAN/INN)
Prestwick0_000225
Prestwick1_000225
Prestwick2_000225
Prestwick3_000225
Spectrum2_000860
Spectrum3_001575
Spectrum4_000848
Spectrum5_000972
N-Nicotinoylaminoantipyrine
Oprea1_385416
SCHEMBL25945
BSPBio_000269
BSPBio_003110
KBioGR_001455
KBioSS_002055
MLS000768954
DivK1c_000546
SPECTRUM1503230
SPBio_000879
SPBio_002190
Nifenazone, analytical standard
BPBio1_000297
CHEMBL1413176
UNII-8780F0K71U
CHEBI:31910
HMS501L08
KBio1_000546
KBio2_002055
KBio2_004623
KBio2_007191
KBio3_002610
M02AA24
N02BB05
NINDS_000546
HMS1568N11
HMS1922K15
HMS2095N11
HMS2796P15
HMS3712N11
Pharmakon1600-01503230
Tox21_110519
CCG-40077
NSC758411
STK733507
AKOS001038391
Tox21_110519_1
DB13407
IDI1_000546
NCGC00016605-02
NCGC00016605-03
NCGC00016605-04
NCGC00016605-05
NCGC00016605-08
NCGC00095026-01
NCGC00095026-02
NCGC00178289-01
NCGC00178289-02
DA-56175
HY-17475
MS-24466
SMR000433688
SBI-0051796.P002
CS-0009213
NS00010564
SW196756-3
D01437
G12495
AB00052331_09
AB00052331_10
EN300-7494160
Q646567
SR-01000632824-1
SR-01000632824-3
SR-01000632824-4
BRD-K47407372-001-05-6
BRD-K47407372-001-09-8
BRD-K47407372-001-15-5
BRD-K47407372-001-16-3
BRD-K47407372-001-17-1
Z27661938
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-nicotinamide
3-Pyridinecarboxamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)nicotinamide #
N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-pyridinecarboxamide (9CI)
218-387-1