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Pyrrolidine derivative

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Identification
Molecular formula
C26H33N3O6S
CAS number
123456-78-9
IUPAC name
N-[1-formyl-3-(methanesulfonamido)-3-oxo-propyl]-1-[3-methyl-2-(naphthalene-2-carbonylamino)butanoyl]pyrrolidine-2-carboxamide
State
State

At room temperature, this compound is typically in a solid state.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.20
Boiling point (Celsius)
240.50
Boiling point (Kelvin)
513.60
General information
Molecular weight
551.63g/mol
Molar mass
551.6340g/mol
Density
1.3000g/cm3
Appearence

This compound typically presents as a white to off-white solid powder.

Comment on solubility

Solubility of N-[1-formyl-3-(methanesulfonamido)-3-oxo-propyl]-1-[3-methyl-2-(naphthalene-2-carbonylamino)butanoyl]pyrrolidine-2-carboxamide

The solubility of the compound N-[1-formyl-3-(methanesulfonamido)-3-oxo-propyl]-1-[3-methyl-2-(naphthalene-2-carbonylamino)butanoyl]pyrrolidine-2-carboxamide (C26H33N3O6S) can be influenced by several factors due to its complex structure and functional groups. Understanding its solubility can help in determining its utility in various applications. Here are a few key points to consider:

  • Polar and Nonpolar Interactions: The presence of the polar methanesulfonamido and carboxamide groups enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: This compound could form hydrogen bonds, which is crucial for solubility in aqueous environments. These interactions could increase solubility significantly compared to purely hydrophobic compounds.
  • Effect of Aromatic Rings: The naphthalene moiety might introduce hydrophobic characteristics that can make solubility in nonpolar solvents favorable, but may hinder solubility in polar solvents.
  • Solvent Dependency: Solubility can vary greatly between different solvents. It is likely to be more soluble in dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) compared to water.

In conclusion, while the compound has potential for solubility in polar solvents due to its functional groups, the presence of large hydrophobic aromatic regions may present challenges in aqueous solubility. Further experimental studies would be necessary to establish precise solubility parameters.

Interesting facts

Interesting Facts about N-[1-formyl-3-(methanesulfonamido)-3-oxo-propyl]-1-[3-methyl-2-(naphthalene-2-carbonylamino)butanoyl]pyrrolidine-2-carboxamide

This compound, with its intricate structure and diverse functional groups, represents a fascinating area of study in pharmaceutical chemistry. It showcases the potential for developing complex biomolecules that can interact with specific biological targets.

Key Features:

  • Drug Design: The compound is a promising candidate for drug design, highlighting the principles of structure-activity relationships (SAR). Its specific modifications may enhance the selectivity and potency of therapeutic agents.
  • Biological Activity: It is expected to exhibit a range of biological activities due to the presence of the -NH and -COOH functional groups, which are known to be crucial in enzyme interactions and receptor binding.
  • Sulfonamide Moiety: The methanesulfonamido group is of particular interest as sulfonamides generally exhibit antibacterial properties. This compound may therefore be investigated for its efficacy against certain strains of bacteria.
  • Naphthalene Unit: The inclusion of the naphthalene ring is significant for enhancing hydrophobic interactions, potentially improving the compound’s bioavailability and interaction with lipid membranes.

As scientific exploration continues, it's imperative to understand how such compounds can lead to new drug formulations, allowing for improved treatments of various diseases. As emphasized by experts in the field, “The future of drug discovery lies in the exploration of complex molecules, such as this one, which could unlock new avenues for therapies.”

Research methodologies like computational chemistry and structure elucidation techniques will be crucial in studying this compound further, helping to predict its behavior in biological systems and paving the way for future innovations in pharmacology.

Synonyms
PD193979