Skip to main content

Becaplermin

ADVERTISEMENT
Identification
Molecular formula
C19H21N5O7
CAS number
221227-05-0
IUPAC name
N-[1-[(1-formyl-4-guanidino-butyl)carbamoyl]-3-methyl-butyl]-4-methyl-2-(propanoylamino)pentanamide
State
State

At room temperature, becaplermin is generally found as a solid. In pharmaceutical applications, it is typically formulated as a gel for easier application to the skin.

Melting point (Celsius)
159.50
Melting point (Kelvin)
432.65
Boiling point (Celsius)
315.85
Boiling point (Kelvin)
589.00
General information
Molecular weight
667.83g/mol
Molar mass
667.8260g/mol
Density
1.2100g/cm3
Appearence

Becaplermin is typically a colorless or white solid when in its pure form. However, it may appear as a white to off-white powder when used in pharmaceutical formulations.

Comment on solubility

Solubility of N-[1-[(1-formyl-4-guanidino-butyl)carbamoyl]-3-methyl-butyl]-4-methyl-2-(propanoylamino)pentanamide

The solubility of the compound N-[1-[(1-formyl-4-guanidino-butyl)carbamoyl]-3-methyl-butyl]-4-methyl-2-(propanoylamino)pentanamide, with the chemical formula C19H21N5O7, is quite intriguing due to its complex structure. Understanding its solubility can provide essential insights into its behavior in various environments. Here are some key points regarding its solubility:

  • Polarity: The presence of various functional groups, such as amides and guanidines, suggests that this compound may exhibit considerable polar characteristics, which could enhance its solubility in polar solvents such as water.
  • Hydrophobic interactions: The long hydrocarbon chains present in the structure may lead to hydrophobic interactions that could decrease solubility in highly polar solvents.
  • Potential solubility in organic solvents: Given the presence of non-polar groups, the compound might also have reasonable solubility in organic solvents, such as ethanol or dimethyl sulfoxide (DMSO).
  • Temperature dependence: Like many compounds, its solubility may vary with temperature; generally, increased temperature can enhance solubility due to increased molecular motion.
  • pH influence: The guanidine functional group may alter the compound’s solubility based on the pH of the surrounding environment, often increasing solubility under acidic or basic conditions.

In conclusion, while the solubility of this compound may lean toward the polar side, the presence of hydrophobic regions allows for versatility in solvent interactions, making it essential to evaluate solubility in different media and conditions for practical applications.

Interesting facts

Interesting Facts about N-[1-[(1-formyl-4-guanidino-butyl)carbamoyl]-3-methyl-butyl]-4-methyl-2-(propanoylamino)pentanamide

N-[1-[(1-formyl-4-guanidino-butyl)carbamoyl]-3-methyl-butyl]-4-methyl-2-(propanoylamino)pentanamide is a fascinating and complex organic compound with a rich structure and potential applications that draw interest from various fields, including medicinal chemistry and biochemistry.

Unique Structural Features

  • Guanidine Group: The presence of a guanidino functional group contributes to the compound's high polar character and potential biological activity.
  • Carbamoyl Linkage: This feature can enhance the compound's ability to function in physiological environments, making it an interesting subject for drug design.
  • Methyl and Propanoyl Substituents: These groups play a crucial role in defining the compound's physical and chemical properties, influencing its interactions with other molecules.

Potential Applications

This compound’s structure suggests several possible applications, including:

  • Pharmaceutical Research: It may serve as a lead compound in designing new drugs targeting specific enzymes or receptors.
  • Biochemical Studies: Understanding its interactions could shed light on cellular mechanisms or metabolic pathways.
  • Research in Protein Design: Due to its guanidinium component, it could be explored for its effects on protein folding and function.

Scientific Implications

From a scientific perspective, studying N-[1-[(1-formyl-4-guanidino-butyl)carbamoyl]-3-methyl-butyl]-4-methyl-2-(propanoylamino)pentanamide opens up several intriguing questions:

  • Interactions with Biological Systems: How does it interact at a cellular level?
  • Mechanism of Activity: What pathways does it influence or modulate?
  • Structure-Activity Relationship (SAR): How do modifications to its structure impact its biological activity?

In summary, the detailed exploration of N-[1-[(1-formyl-4-guanidino-butyl)carbamoyl]-3-methyl-butyl]-4-methyl-2-(propanoylamino)pentanamide holds significant promise for numerous scientific disciplines and could lead to groundbreaking discoveries in drug development and molecular biology.

Synonyms
N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methyl-2-(propanoylamino)pentanamide