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Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid

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Identification
Molecular formula
C6H12NO2P
CAS number
112915-05-2
IUPAC name
methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
State
State

At room temperature, the methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid is in a solid state. It is stable under standard temperature and pressure conditions. The state may depend on external factors such as humidity and presence of solvents, which can influence its morphology and stability.

Melting point (Celsius)
142.30
Melting point (Kelvin)
415.45
Boiling point (Celsius)
308.20
Boiling point (Kelvin)
581.35
General information
Molecular weight
177.17g/mol
Molar mass
177.1710g/mol
Density
1.2431g/cm3
Appearence

Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid typically appears as a solid compound with a crystalline form. The color of the compound can range from white to off-white. The solid form may vary based on purity and crystal formation methods.

Comment on solubility

Solubility of Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic Acid

The solubility of methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid (C6H12NO2P) can be quite intriguing due to its unique structure. This compound, characterized by its phosphinic acid group and a cyclic amine, exhibits the following solubility features:

  • Solvent Compatibility: methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid is expected to be soluble in polar solvents such as water and methanol, owing to its hydrophilic functional groups.
  • Temperature Influence: The solubility may increase with temperature, making it more soluble in heated solvents compared to cold ones.
  • pH Dependence: Being a phosphinic acid, its solubility might be affected by pH changes; higher solubility can occur in more alkaline conditions when the acid group deprotonates.
  • Concentration Effects: At higher concentrations, solubility can be impacted due to saturation limits, leading to potential precipitation if the solubility threshold is exceeded.

In summary, while the solubility of methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid can be favorable in suitable solvents, various factors such as temperature, pH, and concentration should be considered to optimize the conditions. Understanding these variables is essential for practical applications involving this compound.

Interesting facts

Interesting Facts about Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic Acid

Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid is a fascinating compound with several noteworthy features that make it a subject of interest in both organic chemistry and medicinal chemistry. Here are some compelling aspects:

  • Phosphorus-containing Compounds: This compound belongs to a class of phosphorus-containing compounds known for their diverse applications in agriculture and pharmaceuticals.
  • Structural Complexity: The structure includes a tetrahydropyridine ring, which contributes to interesting stereoelectronic properties, making it valuable for designing biologically active molecules.
  • Biological Relevance: Compounds similar to this one often serve as important intermediates in the synthesis of drugs that target neurological disorders, showcasing its potential significance in medicinal chemistry.
  • Versatile Functional Groups: The presence of both phosphinic acid and nitrogen functionalities allows for potential interactions with biological macromolecules, opening doors for applications in drug design.

Moreover, the ability of phosphinic acids to act as enzyme inhibitors highlights their relevance in biochemical studies. As synthesized and studied in laboratories, compounds like methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid pave the way for novel discoveries.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This compound exemplifies this philosophy in action, inspiring ongoing research and exploration.

Synonyms
TPMPA
182485-36-5
methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
Tpmpa [MI]
Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-
UNII-TR7I0800L2
(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid
TR7I0800L2
CHEMBL397209
P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid
DTXSID801017153
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinicacid
P-methyl-1,2,3,6-tetrahydropyridin-1-ium-4-phosphinate
TPMPA?
Biomol-NT_000236
SCHEMBL678239
BPBio1_000464
MFUKVPOVVKKLRQ-UHFFFAOYSA-N
DTXCID201475337
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid hydrate
HHA48536
BDBM50211642
AKOS006344745
NCGC00163284-01
DA-68292
HY-101359
CS-0021216
EN300-310265
SR-01000075623
Q4540639
SR-01000075623-1
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinsaure
Methyl(1,2,3,6-tetrahydropyridinium-4-yl)phosphinate
Methyl(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid
1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid; TPMPA
VZA