Interesting facts
Interesting Facts about Methyl 4-Hydroxybenzoate
Methyl 4-hydroxybenzoate, commonly known as methylparaben, is a fascinating compound widely utilized in various industries. Here are some intriguing aspects about this compound:
- Preservative Power: Methylparaben is famous for its antimicrobial properties, making it a popular choice as a preservative in cosmetics, pharmaceuticals, and food products.
- Safety Approved: It has been extensively studied and deemed safe for use by several health organizations, including the FDA and the European Commission.
- Natural Occurrence: Interestingly, methylparaben naturally occurs in some fruits, such as blueberries and raspberries, which adds to its appeal in organic formulations.
- Synergistic Effects: Often combined with other parabens (like propylparaben), methylparaben exhibits synergistic effects that enhance their antimicrobial efficacy.
- Controversy: Despite its widespread use, methylparaben has been at the center of debates regarding skin health and potential hormonal effects, a topic that warrants ongoing research.
It's fascinating to note how methyl 4-hydroxybenzoate stands at the crossroads of consumer safety and scientific innovation. As ongoing research continues to unravel the complexities of its applications and effects, this compound remains a subject of keen interest within both the scientific community and the marketplace.
Synonyms
Methyl 4-hydroxybenzoate
METHYLPARABEN
99-76-3
Methyl paraben
Methyl p-hydroxybenzoate
Nipagin
Methyl parahydroxybenzoate
Tegosept M
Moldex
Maseptol
Preserval M
Methaben
Metoxyde
Preserval
Metaben
Paridol
Septos
Solbrol
Methyl butex
p-Hydroxybenzoic acid methyl ester
p-Methoxycarbonylphenol
Benzoic acid, 4-hydroxy-, methyl ester
Methyl chemosept
p-Carbomethoxyphenol
4-Hydroxybenzoic acid methyl ester
Methyl parasept
Nipagin M
Aseptoform
Methylben
Abiol
Methyl-p-hydroxybenzoate
Methyl p-oxybenzoate
Solbrol M
4-(Methoxycarbonyl)phenol
4-Hydroxybenzoic acid, methyl ester
FEMA No. 2710
Killitol
p-Hydroxybenzoic methyl ester
FEMA Number 2710
MFCD00002352
Methyl ester of p-hydroxybenzoic acid
p-Oxybenzoesauremethylester
Methylparaben e218
NSC 3827
CCRIS 3946
Benzoic acid, p-hydroxy-, methyl ester
HSDB 1184
Methyl paraben (e218)
methyl 4- hydroxybenzoate
UNII-A2I8C7HI9T
NSC-3827
p-Hydroxybenzoic acid, methyl ester
EINECS 202-785-7
A2I8C7HI9T
EPA Pesticide Chemical Code 061201
NSC-406127
BRN 0509801
methyl hydroxybenzoate
DTXSID4022529
INS number 218
CHEBI:31835
Methylis hydroxybenzoas
AI3-01336
INS-218
4-HYDROXY-BENZOIC ACID METHYL ESTER
Methylester kyseliny p-hydroxybenzoove
E218
CHEMBL325372
DTXCID402529
INS NO.218
E-218
NSC3827
EC 202-785-7
4-Hydroxybenzoic acid-methyl ester
NCGC00159376-02
NCGC00159376-04
E 218
METHYLPARABEN (II)
METHYLPARABEN [II]
WLN: QR DVO1
METHYLPARABEN (USP-RS)
METHYLPARABEN [USP-RS]
Methylparaben [USAN]
Caswell No. 573PP
4-Hydroxybenzoic acid-methyl ester 1000 microg/mL in Acetonitrile
METHYL HYDROXYBENZOATE (MART.)
METHYL HYDROXYBENZOATE [MART.]
CAS-99-76-3
SMR000036660
Methyl 4-?Hydroxybenzoate(Methyl Paraben)
METHYL PARAHYDROXYBENZOATE (EP MONOGRAPH)
METHYL PARAHYDROXYBENZOATE [EP MONOGRAPH]
METHYL SALICYLATE IMPURITY C (EP IMPURITY)
METHYL SALICYLATE IMPURITY C [EP IMPURITY]
p-Oxybenzoesauremethylester [German]
Methylparaben [USAN:NF]
PROPYL HYDROXYBENZOATE IMPURITY B (EP IMPURITY)
PROPYL HYDROXYBENZOATE IMPURITY B [EP IMPURITY]
Metagin
METHYL4-HYDROXYBENZOATE
Lexgard M
Paraben M
Methylester kyseliny p-hydroxybenzoove [Czech]
(Methyl Paraben)
Methylparaben, NF
Methylparaben, FCC
4-carbomethoxyphenol
Methylparaben (NF)
Methylparaben (TN)
Solparol (Salt/Mix)
methyl 4-hydoxybenzoate
methyl 4 hydroxybenzoate
methyl 4-hydroxylbenzoate
methyl 4-hydroxy-benzoate
methyl-4-hydroxy-benzoate
Methyl 4-?Hydroxybenzoate
Methyl paraben (Standard)
METHYLPARABEN [MI]
Preserval MS (Salt/Mix)
bmse010009
methyl (4-hydroxy)benzoate
METHYLPARABEN [FCC]
cid_7456
SCHEMBL4440
isLeaf Tattoo Eyebrow Brown
METHYLPARABEN [HSDB]
METHYLPARABEN [VANDF]
MLS001304047
MLS001304187
BIDD:ER0241
4-hydroxybenzoate methyl ester
INS No. 218
METHYL PARABEN [VANDF]
METHYLPARABEN [WHO-DD]
GTPL6273
Methyl parahydroxybenzoate (TN)
HY-N0349R
4-Hydroxybenzoic acid methylester
methyl 4-hydroxybenzenecarboxylate
MSK2509
HMS2883I08
Methyl Paraben, analytical standard
Methyl parahydroxybenzoate (JP17)
4-hydroxy benzoic acid methyl ester
CS-D1181
HY-N0349
Tox21_111616
Tox21_202318
Tox21_300009
BBL005648
BDBM50209100
CK1194
Methyl 4-hydroxybenzoate - BP grade
NSC406127
s3985
STK802470
AKOS000119910
Tox21_111616_1
CCG-266228
DB14212
FM01972
METHYL HYDROXYBENZOATE [WHO-IP]
METHYL P-HYDROXYBENZOATE [FHFI]
METHYL PARAHYDROXYBENZOATE [JAN]
USEPA/OPP Pesticide Code: 061201
Methyl 4-hydroxybenzoate, >=99%, FCC
NCGC00159376-03
NCGC00159376-05
NCGC00159376-06
NCGC00253939-01
NCGC00259867-01
SY006626
BENZOIC ACID,4-HYDROXY,METHYL ESTER
DB-080628
H0216
M2206
Methyl 4-hydroxybenzoate, analytical standard
Methyl 4-hydroxybenzoate, p.a., 98-102%
NS00001849
EN300-15481
isLeaf Long Lasting Waterproof Eyeliner Black
isLeaf Long Lasting Waterproof Eyeliner Brown
METHYLIS HYDROXYBENZOAS [WHO-IP LATIN]
D01400
Methyl 4-hydroxybenzoate, USP, 98.0-102.0%
AK-087/40191206
Methyl paraben;4-Hydroxybenzoic acid methyl ester
Q229987
BRD-K78321730-001-10-8
Methyl 4-hydroxybenzoate, SAJ first grade, >=98.0%
Methyl 4-hydroxybenzoate, tested according to Ph.Eur.
Z19674820
F1908-0119
Methyl 4-hydroxybenzoate, BioXtra, >=99.0% (titration)
Methylparaben, certified reference material, TraceCERT(R)
Methyl 4-hydroxybenzoate, ReagentPlus(R), >=99.0%, crystalline
Methylparaben, United States Pharmacopeia (USP) Reference Standard
InChI=1/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H
Methyl 4-hydroxybenzoate, BioReagent, suitable for insect cell culture
Methyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard
Methylparaben, Pharmaceutical Secondary Standard; Certified Reference Material
202-785-7
Solubility of Methyl 4-Hydroxybenzoate
Methyl 4-hydroxybenzoate, commonly known as methyl paraben, exhibits interesting solubility characteristics that influence its applications across various fields.
In terms of solubility, it can be observed that:
Generally speaking, methyl 4-hydroxybenzoate is considered to be moderately soluble in water, typically ranging from 0.1 to 1 g/100 mL at room temperature. This solubility profile allows it to be effectively utilized as a preservative in cosmetics and pharmaceuticals, while its organics solubility is beneficial for formulation purposes.
To summarize, the solubility properties of methyl 4-hydroxybenzoate are defined by:
Understanding these solubility traits is essential for its practical applications and for enhancing formulation strategies within industrial sectors.