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Vinblastine

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Identification
Molecular formula
C46H58N4O9
CAS number
865-21-4
IUPAC name
methyl 4-hydroxy-8-methyl-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate
State
State

Vinblastine is a solid at room temperature, appearing as a crystalline powder. It is usually handled in the form of its sulfate salt for medical preparations.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
537.20
Boiling point (Kelvin)
810.35
General information
Molecular weight
811.01g/mol
Molar mass
811.0080g/mol
Density
1.3500g/cm3
Appearence

Vinblastine is a white to slightly yellow crystalline powder. It is typically odorless and has been used medicinally in the form of its sulfate, which is white or off-white.

Comment on solubility

Solubility of Methyl 4-hydroxy-8-methyl-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate

The solubility of the compound with the formula C46H58N4O9 can reveal much about its potential applications and behavior in various environments. Understanding solubility is crucial for predicting how this compound interacts with solvents, biological systems, and other chemicals.
Here are some key points regarding its solubility:

  • Polar vs. Non-polar Characteristics: The presence of multiple methoxy groups may impart some polar characteristics, enhancing solubility in polar solvents like water.
  • Hydrophobic Components: With a significant hydrocarbon chain, this compound may exhibit hydrophobic properties, thereby reducing its solubility in aqueous environments.
  • Solvent Dependence: It is likely that this compound will show different solubility levels depending on the solvent used, such as organic solvents (like methanol or ethanol) where it may dissolve more readily.
  • Application Relevance: Its solubility profile could significantly influence its utility in pharmaceutical formulations, particularly in terms of bioavailability and absorption.

In summation, the solubility of methyl 4-hydroxy-8-methyl-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate is multifaceted and likely varies with the choice of solvent. Further empirical analysis would be beneficial to fully chart its solubility characteristics and potential interaction scenarios.

Interesting facts

Exploring Methyl 4-Hydroxy-8-methyl-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate

The compound known as Methyl 4-hydroxy-8-methyl-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate is a fascinating substance that piques the interest of both chemists and biologists alike. This compound belongs to a class of molecules enriched with indole and pyrrolo frameworks, which are prevalent in various natural products and bioactive compounds.

Here are some intriguing aspects of this compound:

  • Complex Structure: Its intricate multi-ring structure makes it a prime candidate for studying diverse chemical reactivity and properties.
  • Potential Biological Activity: Compounds of this nature often exhibit promising pharmacological properties, such as anti-cancer, anti-inflammatory, or anti-oxidant activities.
  • Diverse Applications: Research into derivatives of this compound could lead to advancements in pharmaceuticals, natural product synthesis, or materials science.
  • Indole Influence: The presence of the indole moiety is noteworthy as it is commonly found in many complex alkaloids and is essential for the biological activity in substances like serotonin and tryptophan.

Moreover, the potential for synthetic modification means that researchers can explore a wide range of derivatives and analogs. Enthusiasts are often reminded that "the beauty of chemistry lies in its complexity and the possibilities it holds." Such compounds pave the way for new discoveries and innovations that could significantly impact the scientific landscape.

As chemists continue to explore the depths of compounds like this, the journey promises to unfold new narratives within the realms of medicinal chemistry and natural product research.