Skip to main content

Artemisinin

ADVERTISEMENT
Identification
Molecular formula
C15H22O5
CAS number
63968-64-9
IUPAC name
methyl 3-acetoxy-12,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate
State
State

At room temperature, artemisinin is a solid.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
155.00
Boiling point (Kelvin)
428.15
General information
Molecular weight
282.33g/mol
Molar mass
282.3340g/mol
Density
1.3500g/cm3
Appearence

Artemisinin appears as a white crystalline powder. It is relatively odorless and has a bitter taste.

Comment on solubility

Solubility of Methyl 3-Acetoxy-12,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate

The solubility of the compound Methyl 3-Acetoxy-12,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate with the chemical formula C15H22O5 can be understood through several key aspects:

  • Polarity: The presence of multiple hydroxyl (-OH) groups and a carboxylate moiety suggests that the compound is relatively polar. This increases its affinity for polar solvents like water.
  • Functional Groups: The acetoxy and hydroxyl groups may enhance solubility in organic solvents, making it more soluble in polar organic solvents like methanol or ethanol.
  • Structural Complexity: The intricate bicyclic and tricyclic structure could hinder solubility due to steric hindrance. This means that while some components of the structure favor solubility, others may counteract this effect.
  • Solubility in Different Media: Expected solubility may vary in different media, such as:
    • Water: Moderate to high solubility due to polar functional groups.
    • Organic solvents: Enhanced solubility, particularly in solvents like DMSO or ethanol.

In summary, while Methyl 3-Acetoxy-12,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate is likely to exhibit decent solubility in polar solvents, its complex structure may present some limitations in solubility in pure water. Understanding the solubility profile of this compound is crucial for its application in various fields.

Interesting facts

Exploring Methyl 3-acetoxy-12,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate

Methyl 3-acetoxy-12,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate is a fascinating compound with a complex structure and significant potential in various fields. Here are some intriguing facts about this unique molecule:

  • Complexity of Structure: The compound features multiple functional groups, including acetoxy and hydroxyl groups, contributing to its reactivity and potential biological activity.
  • Natural Products Relationship: Many compounds with similar structures are found in natural products, especially in the realms of plant metabolites and natural medicinal compounds.
  • Potential Biological Properties: Due to its intricate structure, this compound may exhibit interesting biological activities. Compounds with such characteristics are often studied for their potential therapeutic effects.
  • Synthesis Challenges: Synthesizing such complex molecules can present a number of challenges, including the need for specific conditions to ensure the right stereochemistry and functionalization.
  • Applications in Research: Researchers are likely to explore this compound for its potential applications in drug development, particularly in areas like oncology or anti-inflammatory treatments.

This compound's lengthy name may seem intimidating at first, yet it reflects the richness and complexity of chemical nomenclature. As chemistry students and scientists, delving into compounds with elaborate structures like this can enhance our understanding of molecular interactions and inspire new discoveries in medicinal chemistry.

In the words of Dr. Linus Pauling, "The best way to have a good idea is to have lots of ideas." This ethos encourages exploration of compounds such as methyl 3-acetoxy-12,15,16-trihydroxy-9,13-dimethyl-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate, inviting scholars to unlock the mysteries held within its molecular framework.

Synonyms
ISOBRUCEINE B
NSC238181
methyl 15-(acetyloxy)-1,11,12-trihydroxy-2,16-dioxo-13,20-epoxypicras-3-en-21-oate
DTXSID80968432