Pyridine derivative | Solubility of Things

Identification

Molecular formula

C₂₇H₂₇N₃O₅

CAS number

162851-71-2

IUPAC name

methyl 2-benzamido-3-[[6-(2-isopropoxyphenoxy)-3-pyridyl]amino]prop-2-enoate

State

At room temperature, this compound is a solid. It is typically stored in a cool, dry place to preserve its chemical stability and appearance. The compound is not soluble in water, but may dissolve in organic solvents.

Melting point (Celsius)

127.00

Melting point (Kelvin)

400.15

Boiling point (Celsius)

534.20

Boiling point (Kelvin)

807.35

General information

Molecular weight

496.53g/mol

Molar mass

496.5330g/mol

Density

1.2906g/cm³

Appearence

This compound appears as an off-white powder. It may have a slightly yellowish tint depending on the exact formulation and impurities present. The texture can be described as slightly granular or crystalline.

Comment on solubility

Solubility of Methyl 2-benzamido-3-[[6-(2-isopropoxyphenoxy)-3-pyridyl]amino]prop-2-enoate

The solubility characteristics of methyl 2-benzamido-3-[[6-(2-isopropoxyphenoxy)-3-pyridyl]amino]prop-2-enoate (C₂₇H₂₇N₃O₅) can be quite complex due to its intricate molecular structure. Here are several factors to consider:

Polarity: The presence of multiple functional groups, including amide and ester, suggests that this compound may exhibit a degree of polarity.
Solvent Interaction: It may show variable solubility in common organic solvents. For instance:
- Better solubility in polar organic solvents like methanol and ethanol.
- Limited solubility in non-polar solvents, indicating a preference for polar environments.
Temperature Dependence: Solubility could increase with temperature, a common trend among organic compounds.
pH Sensitivity: If dissolved in aqueous environments, the compound’s solubility might be affected by the pH, especially related to the amide and acidic/alkaline balance.

In summary, methyl 2-benzamido-3-[[6-(2-isopropoxyphenoxy)-3-pyridyl]amino]prop-2-enoate is expected to have moderate solubility profiles that vary with changes in solvent type, temperature, and environmental pH. These factors should be thoroughly investigated during practical applications.

Interesting facts

Interesting Facts about Methyl 2-benzamido-3-[[6-(2-isopropoxyphenoxy)-3-pyridyl]amino]prop-2-enoate

Methyl 2-benzamido-3-[[6-(2-isopropoxyphenoxy)-3-pyridyl]amino]prop-2-enoate is a fascinating compound in the realm of medicinal chemistry. It embodies the complexity of organic synthesis and the diversity of functional groups that can be integrated into pharmaceutical molecules. Here are a few notable points about this compound:

Structure and Function: The intricate structure includes components such as benzamide and pyridine, both known for their biological activities. This makes it a potential candidate for drug development.
Drug Design: The presence of multiple functional groups not only poses a challenge in synthesis but also increases the likelihood of *interacting with various biological targets*.
Research Potential: Compounds similar to this one are often studied for their *anti-cancer*, *anti-inflammatory*, or *antimicrobial* properties, opening avenues for significant therapeutic innovations.
Properties of Isopropoxy Group: The isopropoxyphenyl component can enhance the compound's *lipophilicity*, allowing for better permeability through biological membranes, which is a key factor in drug effectiveness.
Future Investigations: Scientists are particularly interested in the *mechanism of action* and *bioavailability* of compounds with such complex architectures, making this a subject of ongoing research.

As we delve deeper into the properties of methyl 2-benzamido-3-[[6-(2-isopropoxyphenoxy)-3-pyridyl]amino]prop-2-enoate, we uncover endless possibilities for therapeutic applications. This compound exemplifies how structural diversity in chemistry can lead to breakthroughs in health science.

Synonyms

DTXSID20179444

methyl 2-benzamido-3-[[6-(2-propan-2-yloxyphenoxy)pyridin-3-yl]amino]prop-2-enoate