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Vinblastine

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Identification
Molecular formula
C46H58N4O9
CAS number
865-21-4
IUPAC name
methyl 2-[13-(10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl)-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]acetate
State
State
Vinblastine is typically in a solid state at room temperature, appearing as a powder. It is not volatile and remains stable under normal conditions.
Melting point (Celsius)
267.00
Melting point (Kelvin)
540.15
Boiling point (Celsius)
353.15
Boiling point (Kelvin)
626.30
General information
Molecular weight
811.01g/mol
Molar mass
811.0120g/mol
Density
1.3500g/cm3
Appearence
The compound appears as a white to off-white, amorphous or crystalline powder.

It is sensitive to light and may degrade upon prolonged exposure, thus it is often stored in a dark container to maintain its stability.

Comment on solubility

Solubility of Methyl 2-[13-(10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl)-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]acetate (C46H58N4O9)

The solubility of complex organic compounds, such as methyl 2-[13-(10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl)-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]acetate, can vary significantly based on multiple factors. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar: The presence of polar functional groups, such as hydroxyl (-OH) and carbonyl (C=O), generally increases solubility in polar solvents (e.g., water).
  • Hydrophobic Regions: Conversely, large hydrophobic (nonpolar) regions, such as alkyl chains, may decrease solubility in polar solvents while enhancing solubility in organic solvents (e.g., ethanol, chloroform).
  • Temperature Impact: Solubility can also be temperature-dependent; increasing the temperature can enhance the solubility of many compounds.
  • pH Sensitivity: The solubility of compounds containing acidic or basic functional groups may also vary significantly with changes in pH.

As a result, it is essential to consider these factors when predicting the solubility of methyl 2-[13-(10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl)-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]acetate. It may be helpful to conduct experimental solubility tests to determine its behavior in various solvents.

Interesting facts

Interesting Facts about Methyl 2-[13-(10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl)-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]acetate

This compound stands out with its complex structure, showcasing the intricacies of organic chemistry. Here are a few *noteworthy* points:

  • Structural Complexity: With a molecular architecture containing multiple rings and functional groups, this compound is a stellar example of *polycyclic compounds* in medicinal chemistry. Its intricate design allows for potential biological interactions that stimulate fascinating research avenues.
  • Functional Groups: The presence of functional groups such as carbamoyl, hydroxy, and methoxy highlights its potential reactivity and versatility in various chemical reactions, opening doors to *synthesis* and applications in different fields.
  • Pharmacological Potential: Given its unique structure, this compound may exhibit interesting pharmacological properties, making it a candidate for drug discovery. Compounds like this are often investigated for *antitumor*, *antifungal*, or *anti-inflammatory* properties.
  • Research Implications: The depth of *structural diversity* in this compound can encourage scientists to explore its mechanisms of action, toxicity, and efficacy in biological systems, contributing to the field of *medicinal chemistry*.

As a chemistry student or researcher, delving into such a compound not only enhances your understanding of *organic structures* but also emphasizes the endless possibilities within chemical research. The synthesis and study of complex organic compounds like this is crucial for advancing our knowledge and paving the way for innovative therapeutic agents.