Clopidol | Solubility of Things

Identification

Molecular formula

C₁₄H₁₁ClO₂

CAS number

2971-90-6

IUPAC name

isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate

State

Clopidol is typically found in a solid state at room temperature. It remains stable under normal conditions and can be safely stored in airtight containers to avoid degradation.

Melting point (Celsius)

109.00

Melting point (Kelvin)

382.15

Boiling point (Celsius)

422.00

Boiling point (Kelvin)

695.15

General information

Molecular weight

308.79g/mol

Molar mass

308.7860g/mol

Density

1.1898g/cm³

Appearence

Clopidol generally appears as a white to off-white crystalline powder. It is often found in a fine, powdery form which can be easily compressed or blended with other substances for use in various applications. Although not completely odorless, it has a faint, almost imperceptible smell.

Comment on solubility

Solubility of Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate

The solubility of isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate (C₁₄H₁₁ClO₂) is a key consideration for its application in various chemical processes. This compound, characterized by its complex structure, exhibits certain solubility behaviors that can influence its utility in formulations.

Factors Influencing Solubility

The solubility of this compound can be influenced by several factors:

Polarity: Given the presence of both hydrophobic aromatic groups and polar functional groups, the solubility in polar solvents like water may be limited, while it might dissolve better in organic solvents.
Steric Hindrance: The bulky isopropyl group can create steric hindrance, potentially affecting its solubility in various mediums.
Temperature: Increasing temperature often enhances solubility for many organic compounds, which could also apply here.

Predicted Solubility

Based on the chemical structure, we can predict that:

The compound may have low solubility in water, due to its nonpolar characteristics.
It is likely to be more soluble in organic solvents like ethanol, acetone, or ethyl acetate.

In practice, determining the exact solubility requires empirical testing under specific conditions. It is important to consider these factors for effective application in chemical reactions and formulations.

Interesting facts

Interesting Facts about Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate

The compound isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate is a fascinating chemical that falls under the category of esters. Its structure is characterized by the presence of a chloro group, which imparts significant properties to the molecule. Here are some engaging facts about this compound:

Applications in Pharmaceuticals: Many compounds with similar structures are explored for their potential in drug development, particularly in the fight against various ailments.
Chlorinated Aromatic Compounds: The inclusion of a chlorobenzoyl group enhances its reactivity and may influence biological activity, making it a compound of interest in the study of medicinal chemistry.
Esters as Fragrance Contributors: Compounds like this are often investigated for their potential use in the fragrance industry, where esters can contribute pleasant scents.
Environmental Considerations: As with many chlorinated compounds, there is ongoing research into the ecological impact, including studies on stability and degradation in various environments.
Structure-Activity Relationship (SAR): The unique arrangement of atoms in this compound allows it to be a subject of SAR studies, which help chemists understand how structural variations affect activity.

This compound is a perfect example of how chemical structure influences its biological and industrial applications. As you dive deeper into the world of chemistry, understanding such compounds can lead to groundbreaking discoveries!

Synonyms

fenofibrate

49562-28-9

Procetofen

Lipantil

Tricor

Lipidil

Antara

Fenobrate

Triglide

Secalip

Fenoglide

Finofibrate

Lipanthyl

Proctofene

Fenogal

Lipirex

Lipoclar

Lipofen

Lipofene

Sedufen

Elasterin

Fenotard

Protolipan

Ankebin

Lipifen

Liposit

Lipsin

Nolipax

Elasterate

Procetofene

Lipidex

Luxacor

Fenofibrato

Fenofibratum

Supralip

Fenofibratum [INN-Latin]

Fenofibrato [INN-Spanish]

Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate

Lipantil (TN)

Antara (micronized)

Tricor (TN)

propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

TRICOR (MICRONIZED)

LF-178

FENOFIBRATE (MICRONIZED)

Fenofibrate micronized

Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate

Procetoken

CCRIS 7282

NSC 281319

2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester

Fenofibrate delayed release

Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate

EINECS 256-376-3

FNF

MFCD00133314

UNII-U202363UOS

BRN 2062462

CHEBI:5001

DTXSID2029874

HSDB 7736

Fenofibrate (Standard)

U202363UOS

Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester

CHEMBL672

Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl ester

MLS000028515

DTXCID209874

Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate

isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

Phenofibrate

Lofibra

EC 256-376-3

Fenofibrate [USAN:USP:INN:BAN]

propan-2-yl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate

NSC-281319

NCGC00015437-10

Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate

SMR000058299

CAS-49562-28-9

C20H21ClO4

Fenofibratum (INN-Latin)

Fenofibrato (INN-Spanish)

Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethylester

FENOFIBRATE (MART.)

FENOFIBRATE [MART.]

FENOFIBRATE (EP MONOGRAPH)

FENOFIBRATE (USP IMPURITY)

FENOFIBRATE [EP MONOGRAPH]

FENOFIBRATE [USP IMPURITY]

Fenomax

Pharmavit

Fulcro

FENOFIBRATE (USP MONOGRAPH)

FENOFIBRATE [USP MONOGRAPH]

Fenofibrate (USAN:USP:INN:BAN)

CIP-Fenofibrate

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methylethyl ester

LCP-FenoChol

LCP-Feno

Triglide (TN)

Fenofibrate IDD-P

Lipofen (TN)

Antara (TN)

SR-01000000091

LF 178

Lipidax

Isopropyl 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionate

propan-2-yl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate

Fenofibrate,(S)

GRS-027

Prestwick_217

Fenofibrate (GMP)

Fenofibratefilm coated

Spectrum_001250

Opera_ID_328

FENOFIBRATE [MI]

Prestwick0_000275

Prestwick1_000275

Prestwick2_000275

Prestwick3_000275

Spectrum2_001390

Spectrum3_001431

Spectrum4_000413

Spectrum5_001479

FENOFIBRATE [INN]

FENOFIBRATE [JAN]

Lopac-F-6020

FENOFIBRATE [HSDB]

FENOFIBRATE [USAN]

F 6020

FENOFIBRATE [VANDF]

SCHEMBL4670

Lopac0_000486

BSPBio_000150

BSPBio_003162

FENOFIBRATE (USP-RS)

FENOFIBRATE [WHO-DD]

KBioGR_000706

KBioSS_001730

MLS001148191

MLS002548878

BIDD:GT0574

DivK1c_000557

SPECTRUM1501010

SPBio_001380

SPBio_002369

FENOFIBRATE [EMA EPAR]

Fenofibrate, >=99%, powder

BPBio1_000166

Fenofibrate (Tricor, Trilipix)

GTPL7186

Fenofibrate (JP18/USP/INN)

HMS501L19

KBio1_000557

KBio2_001730

KBio2_004298

KBio2_006866

KBio3_002382

C10AB05

FENOFIBRATE [ORANGE BOOK]

NINDS_000557

HMS1568H12

HMS1921B17

HMS2090G20

HMS2092B05

HMS2095H12

HMS2231B14

HMS3259K03

HMS3261B13

HMS3369M13

HMS3649D20

HMS3655K12

HMS3712H12

isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate

Pharmakon1600-01501010

ALBB-028958

BCP21243

Tox21_110147

Tox21_300151

Tox21_500486

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester

BDBM50085042

CCG-38996

HY-17356G

HY-17356R

NSC281319

NSC757822

s1794

AKOS005107777

Tox21_110147_1

AB03716

AC-4227

CS-0892

DB01039

FF23253

LP00486

MS-2223

NC00452

NSC-757822

SDCCGSBI-0050470.P004

IDI1_000557

NCGC00015437-01

NCGC00015437-02

NCGC00015437-03

NCGC00015437-04

NCGC00015437-05

NCGC00015437-06

NCGC00015437-07

NCGC00015437-08

NCGC00015437-09

NCGC00015437-11

NCGC00015437-12

NCGC00015437-13

NCGC00015437-14

NCGC00015437-16

NCGC00015437-17

NCGC00015437-31

NCGC00021475-03

NCGC00021475-04

NCGC00021475-05

NCGC00021475-06

NCGC00021475-07

NCGC00021475-08

NCGC00253945-01

NCGC00261171-01

FENOFIBRATE (MICRONIZED) (fenofibrate

Fenofibrate, analytical reference material

HY-17356

SY052561

SBI-0050470.P003

DB-051642

AB00052196

CS-0695026

EU-0100486

F0674

NS00000285

SW196525-4

C07586

D00565

AB00052196-15

AB00052196-16

AB00052196_17

AB00052196_18

Q419724

SR-01000000091-2

SR-01000000091-5

SR-01000000091-6

SR-01000000091-8

BRD-K50388907-001-05-6

BRD-K50388907-001-18-9

BRD-K50388907-001-20-5

BRD-K50388907-001-29-6

BRD-K50388907-001-30-4

SR-01000000091-16

Z1501485369

Fenofibrate, European Pharmacopoeia (EP) Reference Standard

Isopropyl 2-(4-(4-chlorobenzoyl)-phenoxy)-2-methylpropanoate

1-methylethyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoicacidisopropylester

Fenofibrate, United States Pharmacopeia (USP) Reference Standard

Isopropyl (4''-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methyl-ethyl ester

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester

Fenofibrate, Pharmaceutical Secondary Standard; Certified Reference Material

2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYL-PROPANOIC ACID 1-METHYLETHYL ESTER

256-376-3

J3O