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Camptothecin

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Identification
Molecular formula
C20H16N2O4
CAS number
7689-03-4
IUPAC name
isopentyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[3,2-c]quinoline-2-carboxylate
State
State
Camptothecin is a solid at room temperature.
Melting point (Celsius)
264.00
Melting point (Kelvin)
537.00
Boiling point (Celsius)
606.00
Boiling point (Kelvin)
879.00
General information
Molecular weight
348.35g/mol
Molar mass
348.3530g/mol
Density
1.3400g/cm3
Appearence

Camptothecin appears as a pale yellow crystalline solid. It is usually available in a powder form and may exhibit a slight fluorescent property.

Comment on solubility

Solubility of Isopentyl 7,8-Dimethyl-4,5-Dioxo-6H-Pyrano[3,2-c]quinoline-2-Carboxylate

The solubility behavior of isopentyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[3,2-c]quinoline-2-carboxylate (C20H16N2O4) can be quite intriguing. Understanding the solubility of this compound is essential for its applications in medicinal chemistry and material science. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Solvents: This compound has a significant number of non-polar carbon chains, suggesting that it might exhibit better solubility in organic solvents such as ethanol or chloroform over more polar solvents like water.
  • Temperature Influence: The solubility of organic compounds generally increases with temperature. Therefore, heating the solvent may enhance the dissolution process of this compound.
  • Functional Groups: The presence of carboxylate groups may contribute to some level of hydrophilicity, allowing the compound to interact somewhat with polar solvents.
  • pH Dependency: Alterations in pH levels can also impact solubility due to protonation or deprotonation of functional groups.

In conclusion, while isopentyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[3,2-c]quinoline-2-carboxylate may have limited solubility in water, it is expected to dissolve effectively in polar organic solvents under suitable conditions. The observation of solubility patterns can provide valuable insights into the compound's reactivity and potential applications.

Interesting facts

Interesting Facts about Isopentyl 7,8-Dimethyl-4,5-dioxo-6H-Pyrano[3,2-c]quinoline-2-carboxylate

Isopentyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[3,2-c]quinoline-2-carboxylate is a fascinating compound with potential applications in various fields. Below are some intriguing aspects of this compound:

  • Chemical Structure: The compound features a unique combination of a pyran ring and a quinoline moiety, providing it with interesting chemical properties that could facilitate reactions such as nucleophilic substitutions or cycloadditions.
  • Potential Biological Activity: Many derivatives of quinoline are known for their biological activities. Research has shown that compounds similar to this may exhibit antimicrobial, anti-inflammatory, and even anticancer properties.
  • Applications in Organic Synthesis: The presence of multiple functional groups suggests that it could serve as a valuable intermediate in organic synthesis, allowing the construction of more complex molecular architectures.
  • Environmental Considerations: As environmental concerns grow, compounds like this one are often studied for their potential degradation pathways, involving factors such as photostability and biodegradability.

In summary, Isopentyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[3,2-c]quinoline-2-carboxylate is a compound worth investigating due to its unique structure and potential utility in medicinal and synthetic chemistry. As stated by many chemists, “Understanding the intricate details of such compounds can lead to groundbreaking discoveries.”

Synonyms
repirinast
73080-51-0
MY-5116
Isopentyl 7,8-dimethyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-2-carboxylate
Repirinast (>80%)
3-methylbutyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[3,2-c]quinoline-2-carboxylate
4K8KA8B61G
Repirinastum
Repirinastum [INN-Latin]
3-methylbutyl 5-hydroxy-7,8-dimethyl-4-oxopyrano[3,2-c]quinoline-2-carboxylate
Repirinast [USAN:INN:JAN]
BRN 4267921
UNII-4K8KA8B61G
REPIRINAST [MI]
REPIRINAST [INN]
REPIRINAST [JAN]
REPIRINAST [USAN]
REPIRINAST [MART.]
Isoamyl 5,6-dihydro-7,8-dimethyl-4,5-dioxo-4H-pyrano(3,2-c)quinoline-2-carboxylate
Isopentyl 5,6-dihydro-7,8-dimethyl-4,5-dioxo-4H-pyrano(3,2-c)quinoline-2-carboxylate
REPIRINAST [WHO-DD]
SCHEMBL29997
Repirinast (JAN/USAN/INN)
CHEMBL2105300
CHEBI:32092
DTXSID10223349
BCP16315
EX-A3508
AKOS016014130
AC-5020
FR27702
4H-Pyrano(3,2-c)quinoline-2-carboxylic acid, 5,6-dihydro-7,8-dimethyl-4,5-dioxo-, 3-methylbutyl ester
4H-Pyrano(3,2-c)quinoline-2-carboxylic acid, 5,6-dihydro-7,8-dimethyl-4,5-dioxo-, isopentyl ester
DB-055720
HY-109544
CS-0031286
NS00123728
D01890
Q7314016
5,6-Dihydro-7,8-dimethyl-4,5-dioxo-4H-pyrano[3,2-c]quinoline-2-carboxylic acid 3-methylbutyl ester;MY 5116;Romet