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Hydroxylamine

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Identification
Molecular formula
NH2OH
CAS number
7803-49-8
IUPAC name
hydroxylamine
State
State

At room temperature, hydroxylamine can exist as a white crystalline solid. In its most common form, it is encountered as an aqueous solution, which is safer to handle than the dry compound.

Melting point (Celsius)
33.00
Melting point (Kelvin)
306.15
Boiling point (Celsius)
58.00
Boiling point (Kelvin)
331.15
General information
Molecular weight
33.03g/mol
Molar mass
33.0310g/mol
Density
1.2100g/cm3
Appearence

Hydroxylamine typically appears as a colorless, crystalline solid or a clear liquid in its aqueous solution form. It is known for its instability and can be hazardous if mishandled. As a pure solid, it may decompose violently.

Comment on solubility

Solubility of Hydroxylamine (NH2OH)

Hydroxylamine, with the chemical formula NH2OH, is known for its significant solubility characteristics. Understanding its solubility is crucial for various applications in chemistry and biochemistry. Here are some key points regarding the solubility of hydroxylamine:

  • Solubility in Water: Hydroxylamine is highly soluble in water, forming a stable solution. This is due to the strong hydrogen bonding abilities of the hydroxyl group.
  • Temperature Dependency: The solubility of hydroxylamine increases with temperature. Higher temperatures can enhance molecular interactions, leading to improved solubility.
  • Polar Nature: Being a polar compound, hydroxylamine interacts favorably with polar solvents, which facilitates its dissolving process.
  • Other Solvents: Hydroxylamine is also soluble in alcohols and certain organic solvents, but its solubility in non-polar solvents is significantly low.

As a general rule, the greater the polarity of the solvent, the better the solubility of hydroxylamine. This makes it an essential compound in various fields such as organic synthesis, where its solubility properties can influence reaction conditions and outcomes.

Interesting facts

Interesting Facts about Hydroxylamine

Hydroxylamine is a fascinating compound that has garnered interest in various fields of chemistry and biochemistry. Here are some key points that highlight its significance:

  • Versatile Reagent: Hydroxylamine is widely recognized as a versatile reagent in organic synthesis. It is used to convert carbonyl compounds into oximes, paving the way for further chemical transformations.
  • Biological Relevance: This compound plays a crucial role in biological systems, particularly in the metabolism of nitrogenous compounds. In addition, it has been utilized in some biochemical assays to measure certain types of enzymes.
  • Industrial Applications: Hydroxylamine is employed in the manufacturing process of pharmaceuticals, agricultural chemicals, and other fine chemicals. Its ability to act as a reducing agent is particularly valuable in these sectors.
  • Stability Concerns: Despite its usefulness, hydroxylamine can be unstable and hazardous under certain conditions, especially in its pure form. It has reactive properties that warrant careful handling and specific storage conditions.
  • Research Interest: Ongoing research is exploring hydroxylamine's potential as a therapeutic agent in treating oxidative stress-related diseases. Its antioxidant properties may contribute to mitigating cellular damage.

Overall, hydroxylamine can be viewed as a chemical chameleon, participating in various chemical reactions while also holding potential in industrial and medical applications. As the quote goes, "Every compound has a story to tell," and hydroxylamine's story is one of versatility and promise.

Synonyms
hydroxylamine
7803-49-8
Oxammonium
Nitroxide
HYDROXYAMINE
NH2OH
Oxyammonia
Hydroxylamin
HSDB 579
dihydridohydroxidonitrogen
EINECS 232-259-2
UNII-2FP81O2L9Z
2FP81O2L9Z
CHEBI:15429
H2NHO
11104-93-1
DTXSID7041043
EC 232-259-2
Hydroxylamine, 50 wt. % solution in water
(NH2OH)
[NH2OH]
oxidoazanium
Hydroxylamine Solution (50 wt. % in H2O)
arninoalcohol
hyroxylamine
amino alcohol
amino-alcohol
hydroxy amine
hydroxyl amine
hydroxyl-amine
azinous acid
N-hydroxyamine
amine N-oxide
(1) hydroxylamine
MFCD00044522
H2NOH
HONH2
Lopac-H-9876
HYDROXYLAMINE [MI]
Epitope ID:117722
H2N-OH
HYDROXYLAMINE [HSDB]
Lopac0_000637
N H2 O H
CHEMBL1191361
DTXCID5021043
BCP03655
BDBM50082140
AKOS009031565
CCG-204724
SDCCGSBI-0050617.P002
MRF-0000034
NCGC00015527-01
NCGC00015527-02
NCGC00015527-03
NCGC00015527-05
NCGC00162208-01
11129-69-4
13408-29-2
DB-080981
NS00009755
C00192
Q259997
Q27110260
Q27110261
2FFDCFE4-66E9-4869-8F4D-DC8E410797E7
Hydroxylamine hydrochloride in combination with isoniazid and rifampicin
232-259-2