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Zalcitabine

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Identification
Molecular formula
C9H13N3O3
CAS number
7481-89-2
IUPAC name
[hydroxy-[[3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy]phosphoryl] (3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl) hydrogen phosphate
State
State

At room temperature, zalcitabine is a solid.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.00
Boiling point (Celsius)
491.00
Boiling point (Kelvin)
764.00
General information
Molecular weight
211.22g/mol
Molar mass
211.2210g/mol
Density
2.1000g/cm3
Appearence

Zalcitabine appears as a white crystalline powder.

Comment on solubility

Solubility of Hydroxy-Phosphate Compound

The solubility of the compound with the chemical formula C9H13N3O3, which features a complex structure, is influenced by several factors. Understanding these factors can help predict how this compound behaves in various environments.

Factors Influencing Solubility:

  • Polarity: This compound contains hydroxyl groups (-OH), which typically enhance solubility in polar solvents like water.
  • Ionic Characteristics: The presence of phosphate groups can increase solubility in aqueous solutions, as they can dissociate to release ions.
  • Molecular Interactions: Intermolecular forces, such as hydrogen bonding, can also facilitate solubility, making compounds like this more likely to dissolve in suitable solvents.

It's noteworthy to mention that the solubility can vary significantly in different solvent systems:

  • Water: Likely to exhibit reasonable solubility due to its hydrophilic nature.
  • Organic Solvents: May have limited solubility depending on the solvent's polarity.
  • Buffer Solutions: Might enhance solubility, especially in biological systems, where pH can impact ionization.

In summary, the solubility of this hydroxy-phosphate compound is a result of its intricate molecular interactions and the presence of functional groups that promote interactions with solvents. As highlighted, the ability to solvate in water and other environments is critical to its potential applications.

Interesting facts

Interesting Facts about Hydroxy-Phosphoryl Compound

This complex compound, given its long and intriguing name, showcases the sophisticated interplay of organic and inorganic chemistry. Here's what makes this compound particularly fascinating:

  • Diverse Functional Groups: This compound contains multiple functional groups including hydroxyl, methoxy, and phosphonate groups, demonstrating the versatility of organic synthesis.
  • Biological Relevance: The structure hints at potential biological activity. Many compounds with similar motifs are implicated in essential biological processes, such as nucleotide metabolism and cellular signaling pathways.
  • Pharmaceutical Potential: The presence of the pyrimidine and tetrahydropyran rings suggests it could serve as a lead structure in drug development, particularly in combating diseases where these motifs show therapeutic utility.
  • Stability and Reactivity: The phosphonate moiety is known for its stability under various conditions, making compounds like this significant in fields like biochemistry and pharmacology. It might resist hydrolysis, which is an appeal for drug formulations.
  • Research Interest: Compounds with such unique architectures are often subjects of intense research; they can inspire new synthetic methodologies or result in the discovery of new chemical behaviors.

In conclusion, this hydroxy-phosphoryl compound is not just a complex structure, but a potential key to unlocking new discoveries in both organic chemistry and drug development. As quoted by a renowned chemist, "Every compound has a story to tell, each connecting the dots in the grand narrative of molecular interactions."

Synonyms
PD041132