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Ethyl N-(phthalazin-1-ylamino)carbamate

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Identification
Molecular formula
C12H13N3O2
CAS number
25554-00-7
IUPAC name
ethyl N-(phthalazin-1-ylamino)carbamate
State
State

At room temperature, ethyl N-(phthalazin-1-ylamino)carbamate is in a solid state.

Melting point (Celsius)
134.50
Melting point (Kelvin)
407.65
Boiling point (Celsius)
361.50
Boiling point (Kelvin)
634.65
General information
Molecular weight
259.26g/mol
Molar mass
259.2620g/mol
Density
1.3100g/cm3
Appearence

Ethyl N-(phthalazin-1-ylamino)carbamate typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of Ethyl N-(phthalazin-1-ylamino)carbamate (C12H13N3O2)

Ethyl N-(phthalazin-1-ylamino)carbamate exhibits interesting solubility characteristics that are vital for its potential applications. Understanding the solubility of this compound involves an exploration of various factors:

  • Polarity: The presence of functional groups such as the carbamate and the phthalazin moiety influences the polarity of the compound, typically enhancing solubility in polar solvents.
  • Solvents: It is likely soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), while being less soluble in non-polar solvents.
  • pH Dependency: Solubility may vary with pH, especially considering the amino group, which can protonate or deprotonate depending on the solution's acidity.
  • Temperature: Solubility can also increase with temperature, making it essential to consider conditions in experimental setups.

As highlighted by its structural complexity, this compound's behavior in solution can be described as a combination of interactions facilitated by its molecular architecture. When dealing with solutions, one might say, "Soluble properties define the accessibility of compounds in various chemical contexts." Understanding these solubility characteristics is key in both research and industrial applications.

Interesting facts

Interesting Facts about Ethyl N-(phthalazin-1-ylamino)carbamate

Ethyl N-(phthalazin-1-ylamino)carbamate is a fascinating chemical compound that falls into the category of carbamates. This compound is particularly interesting due to its potential applications and the unique characteristics associated with its structure. Here are some noteworthy points:

  • Pharmaceutical Potential: Compounds like ethyl N-(phthalazin-1-ylamino)carbamate are often explored for their pharmaceutical applications. The presence of the phthalazin moiety suggests it may have biological activity, which is an exciting area for further research.
  • Structural Highlights: The structure of this compound includes a carbamate functional group, which is known for its stability and reactivity, making it an essential component in medicinal chemistry.
  • Research Interest: Given its unique structure, this compound is often a subject of study in laboratory settings, especially in relation to drug design and development.
  • Synthetic Pathways: Scientists continue to investigate efficient synthetic routes to produce this compound, which can provide insights into greener chemistry practices.
  • Mechanistic Studies: The interactions of this compound with biological systems could lead to understanding mechanisms of action that can inform new therapeutic strategies.

As a result of these characteristics, ethyl N-(phthalazin-1-ylamino)carbamate serves not only as a subject of interest for organic chemists but also for those in the pharmaceutical and medicinal fields. The exploration of this compound is a testament to the rich interplay between structure and function in chemistry.

Synonyms
todralazine
14679-73-3
Todralazina
Ecarazine
Todralacina
Carboethoxyphthalazinohydrazine
Binazin
Todralazinum
Todralacina [Spanish]
Ethyl 3-(1-phthalazinyl)carbazate
Todralazine [INN:BAN]
Todralazinum [INN-Latin]
Todralazina [INN-Spanish]
BT 621
CARBAZIC ACID, 3-(1-PHTHALAZINYL)-, ETHYL ESTER
UNII-WEN3K83YKD
WEN3K83YKD
3-(1-Phthalazinyl)carbazic acid ethyl ester
Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester
N-Carboethoxy-N'-phthalazino-hydrazine
Todralazine (BAN)
BRN 0233300
CEPH [AS HYDROCHLORIDE]
Binazine (Salt/Mix)
Ecarazine (Salt/Mix)
CEPH FREE BASE
Todrazoline (Salt/Mix)
TODRALAZINE [MI]
BT 621 [AS HYDROCHLORIDE]
TODRALAZINE [INN]
NSC-757868
BT-621 FREE BASE
TODRALAZINE [WHO-DD]
DTXSID0045048
5-25-17-00414 (Beilstein Handbook Reference)
NSC 757868
Todralazinum (INN-Latin)
Todralazina (INN-Spanish)
CEPH (AS HYDROCHLORIDE)
Todrazoline
BT 621 (AS HYDROCHLORIDE)
ethyl N-(phthalazin-1-ylamino)carbamate
Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester, monohydrochloride
NCGC00016640-03
CAS-3778-76-5
CEPH
Spectrum_001187
Prestwick0_000071
Prestwick1_000071
Prestwick2_000071
Prestwick3_000071
Spectrum2_001147
Spectrum3_000932
Spectrum4_001031
Spectrum5_001223
SCHEMBL49644
BSPBio_000281
KBioGR_001581
KBioSS_001667
DivK1c_000506
SPBio_001073
SPBio_002202
BPBio1_000311
CHEMBL1079787
DTXCID8025048
CHEBI:94706
KBio1_000506
KBio2_001667
KBio2_004235
KBio2_006803
KBio3_001964
NINDS_000506
HY-B1001
PAA67973
AKOS030526097
CS-4498
IDI1_000506
NCGC00016640-01
NCGC00016640-02
1-(N'-ethoxycarbonylhydrazino)phthalazine
DA-10133
SBI-0051674.P002
AB00053609
NS00126300
D08613
Ethyl 2-(1-phthalazinyl)hydrazinecarboxylate #
AB00053609_08
N-(1-phthalazinylamino)carbamic acid ethyl ester
CU-00000000398-1
BRD-K68553471-003-04-0
BRD-K68553471-003-07-3
BRD-K68553471-003-12-3
Q27166508
Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester (9CI)
Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester, monohydrochloride (9CI)