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Promethazine ethyl sulfate

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Identification
Molecular formula
C20H24N2OS2
CAS number
7525-50-2
IUPAC name
ethyl-dimethyl-(2-phenothiazin-10-ylpropyl)ammonium;ethyl sulfate
State
State

Under standard conditions for temperature and pressure, Promethazine ethyl sulfate is in a solid state. It is stable under most ambient conditions but should be kept away from excessive heat, light, and moisture to prevent decomposition and ensure longevity.

Melting point (Celsius)
60.00
Melting point (Kelvin)
333.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
358.51g/mol
Molar mass
358.5140g/mol
Density
1.2500g/cm3
Appearence

Promethazine ethyl sulfate is typically found as a white to slightly yellow, crystalline powder. It may also appear as granules, depending on the specific preparation and manufacturer. The compound is usually odorless.

Comment on solubility

Solubility of Ethyl-dimethyl-(2-phenothiazin-10-ylpropyl)ammonium;ethyl sulfate

The solubility of the compound ethyl-dimethyl-(2-phenothiazin-10-ylpropyl)ammonium;ethyl sulfate, with the chemical formula C20H24N2OS2, can be quite interesting due to its unique molecular structure.

Key factors affecting solubility include:

  • Polarity: The presence of both a quaternary ammonium group and a sulfate group contributes to the overall polarity of the molecule. Generally, polar compounds tend to dissolve well in polar solvents.
  • Hydrophobic structures: The phenothiazine moiety adds a hydrophobic character, which may limit solubility in aqueous solutions.
  • Temperature: Solubility can increase with temperature; thus, heating the solvent might facilitate better dissolution of the compound.

In aqueous environments, it is likely that the compound exhibits better solubility due to the ionic nature of the sulfate group, enabling it to interact favorably with water molecules. However, the extent of solubility will also depend on factors such as:

  • pH level: Changes in pH can affect the ionization of the ammonium group, influencing solubility even further.
  • Presence of other ions: The solubility may also be affected by competing ions in the solution, which can stabilize or destabilize the compound in solution.

Overall, preparing solutions of this compound will require careful consideration of the solvent environment to effectively manage its solubility characteristics. Understanding these factors is crucial for any practical applications involving ethyl-dimethyl-(2-phenothiazin-10-ylpropyl)ammonium;ethyl sulfate.

Interesting facts

Interesting Facts about Ethyl-dimethyl-(2-phenothiazin-10-ylpropyl)ammonium;ethyl sulfate

Ethyl-dimethyl-(2-phenothiazin-10-ylpropyl)ammonium;ethyl sulfate is a fascinating compound, especially notable in the realm of medicinal chemistry and pharmacology. Here are some engaging insights:

  • Pharmacological Potential: Compounds containing phenothiazines are renowned for their applications in treating psychiatric disorders, notably as antipsychotic agents. This compound may share similar therapeutic properties.
  • Unique Structure: The presence of a phenothiazine moiety contributes to its biological activity. These structures are noted for their ability to intercalate into DNA and modulate various cellular processes.
  • Quaternary Ammonium Compound: Being a quaternary ammonium compound, it illustrates significant activity in antimicrobial applications, enhancing its utility in various fields, including materials science and medicine.
  • Sulfate Group Influence: The ethyl sulfate part of the compound enhances solubility and helps in facilitating the transportation of the molecule across biological membranes, which can be crucial for its efficacy as a drug.
  • Research Applications: This compound is not just a passive actor in the lab; it is often explored for its potential to function as a model in studies related to receptor binding and drug delivery systems.

As stated by researchers, "the integration of ethyl and dimethyl groups brings forth a versatile interaction landscape, making such compounds pivotal in drug design." This highlights the intricate balance between structural innovation and functionality that chemists strive to achieve in compound development.

The ongoing research into such compounds sheds light on their multifaceted roles and promises the potential for significant advancements in therapeutic strategies.

Synonyms
57-98-7
AMMONIUM, ETHYLDIMETHYL(2-PHENOTHIAZIN-10-YLPROPYL)-, ETHYL SULFATE
WU 2506
10H-Phenothiazine-10-ethanaminium, N-ethyl-N,N,beta-trimethyl-, ethyl sulfate
N-(2-Dimethyl-aethylammonium-1-methylaethyl)-phenothiazin-aethosulfat [German]
n-ethyl-n,n-dimethyl-2-(10h-phenothiazin-10-yl)propan-1-aminium ethyl sulfate
DTXSID70972487
Ethyldimethyl(2-phenothiazin-10-ylpropyl)ammonium ethyl sulfate
N-(2-Dimethyl-aethylammonium-1-methylaethyl)-phenothiazin-aethosulfat