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Promazine

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Identification
Molecular formula
C17H20N2S
CAS number
58-40-2
IUPAC name
ethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium
State
State
Promazine is a solid at room temperature, typically in the form of a powder.
Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
273.60
Boiling point (Kelvin)
546.80
General information
Molecular weight
284.42g/mol
Molar mass
284.4210g/mol
Density
1.2000g/cm3
Appearence
Promazine appears as a white or off-white crystalline powder. It is typically odorless.
Comment on solubility

Solubility of Ethyl-Dimethyl-(1-Methyl-2-Phenothiazin-10-yl-Ethyl)ammonium (C17H20N2S)

The solubility of ethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium is an intriguing topic. This compound, characterized by its complex structure, shows varying degrees of solubility depending on the solvent used. Here are some key points to consider:

  • Aromatic Structure Influence: The presence of the phenothiazine moiety can affect solubility, as aromatic compounds generally exhibit different solubilities compared to aliphatic counterparts. This may result in limited solubility in nonpolar solvents.
  • Miscibility in Water: Given that ethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium contains nitrogen atoms, it can exhibit some degree of hydrophilicity, suggesting potential solubility in polar solvents, particularly under certain conditions.
  • pH Dependency: The solubility in aqueous solutions can also be influenced by the pH. It may become more soluble in acidic or basic conditions due to ionization, which can enhance its solvation.
  • Temperature Effect: As with many organic compounds, temperature variations can markedly influence solubility, often leading to increased solubility at higher temperatures.

In summary, while ethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium may not be extensively soluble in all solvents, its solubility can be influenced by several factors including solvent choice, pH, temperature, and the intricate nature of its molecular structure. Understanding these dynamics is essential for applications in various chemical processes.

Interesting facts

Interesting Facts about Ethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium

This unique compound is an organic ammonium salt that has garnered significant interest in various fields of study, particularly in medicinal chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: Ethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium is structurally related to phenothiazine derivatives, which are well-known for their antipsychotic and antiemetic properties. This connection opens doors to its potential usage in therapeutic applications.
  • Ionization: As a quaternary ammonium compound, it carries a positive charge, which greatly influences its solubility and interaction with biological membranes, enhancing its ability to cross cellular barriers.
  • Stability and Reactivity: The presence of the phenothiazine moiety adds stability to the compound while also allowing it to engage in various chemical reactions, making it a versatile candidate for further synthesis and modification.
  • Historical Significance: Phenothiazines were first introduced in the 1950s as antipsychotic medications, marking a significant development in psychiatric treatment. The evolution of compounds like this reflects the ongoing innovation in drug discovery.
  • Structure-Activity Relationship (SAR): Researchers often study the SAR of compounds related to phenothiazine to identify structural features that enhance biological activity. Understanding how this compound interacts on a molecular level can lead to optimized therapeutic agents.

As science evolves, compounds such as ethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium could play a crucial role in the development of new medications, advancing our capacity to treat psychological disorders effectively. As we continue to explore its properties and applications, the chemical community remains excited about the potential discoveries that await.