Interesting facts
Interesting Facts about Ethyl 7-Chloro-5-(2-Fluorophenyl)-2-oxo-1,3-Dihydro-1,4-benzodiazepine-3-carboxylate
This compound is part of the benzodiazepine family, which is renowned for its therapeutic properties. Here are some fascinating insights into this particular derivative:
- Structure and Stability: The presence of both a chlorine and a fluorine atom in the structure contributes to its unique pharmacological profile and can enhance stability against metabolic degradation.
- Biological Activity: Compounds structurally related to benzodiazepines are often known for their ability to modulate the action of neurotransmitters in the brain, particularly influencing the gamma-aminobutyric acid (GABA) receptors, which makes them effective anxiolytics and sedatives.
- Chemical Synthesis: The synthesis of this compound may involve multi-step reactions, often including nucleophilic substitutions and cyclization reactions, showcasing the complexity of synthetic organic chemistry.
- Potential Applications: Beyond their use in treating anxiety and insomnia, benzodiazepines are also being explored for their neuroprotective effects and potential use in various chronic diseases.
- Scientific Research: The ongoing study of compounds like this one highlights the importance of structure-activity relationships (SAR) in medicinal chemistry, guiding researchers in the design of new therapeutic agents.
As a part of the ongoing exploration in drug discovery, understanding the nuances of compounds like ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate not only reveals their potential in clinical applications but also enriches our knowledge of chemistry at a molecular level.
Synonyms
ethyl loflazepate
Victan
Meilax
29177-84-2
Ethyl fluclozepate
Loflazepate d'ethyle
Loflazepato de etilo
CM 6912
Loflazepic acid, ethyl ester
Ethylis loflazepas
Ethyl loflazepate [INN:JAN]
Ethylis loflazepas [INN-Latin]
VJB5FW9W9J
Loflazepate d'ethyle [INN-French]
Loflazepato de etilo [INN-Spanish]
EINECS 249-489-4
Meilax (TN)
BRN 0765264
Ethyl 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepine-3-carboxylate
1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-, ethyl ester
ETHYL LOFLAZEPATE [MI]
ETHYL LOFLAZEPATE [INN]
ETHYL LOFLAZEPATE [JAN]
DTXSID60865475
ETHYL LOFLAZEPATE [MART.]
ETHYL LOFLAZEPATE [WHO-DD]
5-25-08-00124 (Beilstein Handbook Reference)
ethyl flucozepate
Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylate
Ethylis loflazepas (INN-Latin)
ETHYL LOFLAZEPATE (MART.)
Loflazepate d'ethyle (INN-French)
Loflazepato de etilo (INN-Spanish)
Ethyl Loflazepate (1.0mg/ml in Acetonitrile)
UNII-VJB5FW9W9J
Azutolem
Medetax
Sukarnase
Bigson
Ronlax
DEA No. 2758
3-Aminophenol 4-Methylbenzenesulfonate (Ester); m-Aminophenol p-Toluenesulfonate; m-Aminophenol p-Toluenesulfonate (Ester)
Ethyl loflazepic acid
CM-6912
ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
SCHEMBL156702
CHEMBL1213460
Ethyl loflazepate (JP18/INN)
CHEBI:31573
DTXCID40813878
N05BA18
DB01545
NS00004645
D01293
Q5404460
Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylate #
(E)-ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepine-3-carboxylate
249-489-4
ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepine-3-carboxylate
Solubility of Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate (C21H23ClFN3O3)
The solubility of ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate is influenced by several factors, including its complex molecular structure. As a benzodiazepine derivative, you can expect the following characteristics regarding its solubility:
In summary, the solubility of C21H23ClFN3O3 is likely to demonstrate:
As a result, determining the optimal solvent for applications involving this compound is crucial for achieving desired concentrations and stability.