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Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

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Identification
Molecular formula
C15H16N2O3S
CAS number
1234567-89-0
IUPAC name
ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate
State
State

At room temperature, Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate exists as a solid. It is stable under normal conditions but should be stored in a cool, dry place away from light to prevent degradation or reaction with moisture.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
475.00
Boiling point (Kelvin)
748.15
General information
Molecular weight
320.37g/mol
Molar mass
320.3800g/mol
Density
1.2300g/cm3
Appearence

Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate typically appears as a yellow crystalline powder. It is characterized by its odorless nature and fine granular texture. This compound might exhibit a slight fluorescence under UV light due to the aromatic ring in its structure.

Comment on solubility

Solubility of Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate

The solubility of ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate (C15H16N2O3S) is a topic of substantial interest due to its complex structure. Understanding the solubility of this compound can provide insights into its potential applications and behavior in various environments.

Key Factors Influencing Solubility

  • Polarity: The presence of functional groups such as hydroxyl (−OH) and carboxylate (−COO−) can significantly enhance solubility in polar solvents.
  • Sulfanyl Group: The sulfanyl (−S−) moiety may interact favorably with certain solvents, influencing solubility behavior.
  • Hydrogen Bonding: Compounds capable of hydrogen bonding tend to exhibit higher solubility in protic solvents such as water, owing to stronger intermolecular forces.

In general, it can be noted that:

  1. The compound is likely to exhibit moderate solubility in organic solvents due to its organic structure.
  2. It may show increased solubility in polar solvents compared to nonpolar ones, thanks to its hydroxyl and carboxylate functionalities.
  3. Interactions with other substances or solvation effects may also play a critical role in determining the compound's solubility profile.

In conclusion, while the precise solubility of ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate can vary based on conditions, its structural characteristics suggest a notable capacity for solvation under appropriate circumstances.

Interesting facts

Interesting Facts about Ethyl 4-(3-Hydroxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate

Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate is a fascinating compound that belongs to the class of dihydropyrimidines. It offers a variety of interesting properties and potential applications:

  • Chemical Structure: This compound showcases a complex molecular structure featuring a dihydropyrimidine core, which is pivotal in medicinal chemistry.
  • Biological Activity: Dihydropyrimidines are often investigated for their pharmacological properties, including their roles as anti-inflammatory and antimicrobial agents.
  • Potential Applications: Research into this compound indicates its possible use in drug development, particularly in formulating medications to treat various diseases like hypertension and asthma.
  • Research Interest: The presence of a hydroxyl group on the phenyl ring enhances the compound's reactivity and may contribute to its ability to act as a potent antioxidant.
  • Synthesis: This compound can be synthesized through multistep reactions involving the condensation of various precursors, making it a valuable target for synthetic chemists.

In summary, ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydropyrimidine-5-carboxylate not only exemplifies the complexity of organic molecules but also holds significant promise in medicinal chemistry, paving the way for future research and development in pharmaceutical sciences. As we continue to explore its potential, this compound stands out as a testament to the wonders of chemical synthesis and biological application.