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ethyl 2,4-dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate

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Identification
Molecular formula
C18H18N2O3
CAS number
/
IUPAC name
ethyl 2,4-dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate
State
State

At room temperature, ethyl 2,4-dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate is typically in a solid state.

Melting point (Celsius)
180.50
Melting point (Kelvin)
453.65
Boiling point (Celsius)
589.23
Boiling point (Kelvin)
862.38
General information
Molecular weight
306.36g/mol
Molar mass
306.3590g/mol
Density
1.2500g/cm3
Appearence
The compound is a crystalline solid that may appear as a fine powder or as small, colorless crystals. It generally exhibits no distinct odor.
Comment on solubility

Solubility of Ethyl 2,4-Dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate

The solubility of the compound ethyl 2,4-dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate (C18H18N2O3) can be influenced by several factors, including its molecular structure and interactions with solvents.

Here are some key points regarding its solubility:

  • Polarity: The presence of various functional groups in the compound contributes to its polarity levels, which can affect solubility in polar versus non-polar solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding with water or other solvents can enhance solubility, particularly if the compound has suitable donor and acceptor sites.
  • Solvent Interaction: The choice of solvent is crucial; compounds like this may display higher solubility in organic solvents such as ethanol and methanol compared to water.
  • Temperature Effects: Higher temperatures often increase solubility for many organic compounds, making the solvation process more favorable.

As a general guideline, compounds that have a higher degree of complexity and structural rigidity, such as crowns or other cyclic systems, may exhibit lower solubility in common solvents due to steric hindrance or increased intermolecular attractions. It is often necessary to conduct empirical testing to determine the exact solubility characteristics of such compounds.

In summary, the solubility of ethyl 2,4-dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate is a multifaceted topic, heavily reliant on its molecular interactions and the nature of the solvent employed. Understanding these dynamics allows for better predictions of its behavior in various chemical environments.

Interesting facts

Interesting Facts About Ethyl 2,4-Dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate

This fascinating compound is a part of the pyrrole family, which is known for its distinctive five-membered aromatic ring containing nitrogen. Here are some intriguing points that highlight its significance:

  • Pyrrole Derivatives: The presence of the pyrrole structure in this compound is noteworthy as pyrrole derivatives play crucial roles in biological systems, pharmaceuticals, and organic materials.
  • Indoline Connection: The compound features a unique 2-oxoindoline segment, which is known for its rich biological activity, including anti-cancer properties and enzyme inhibition.
  • Versatile Applications: Due to its specific structural features, ethyl 2,4-dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate is being researched for its potential application in medicinal chemistry, particularly as a lead compound for developing novel drugs.
  • Synthetic Potential: The synthesis of this compound can serve as a model for designing more complex molecules with tailored properties, enhancing the field of organic synthesis.
  • Biological Relevance: Compounds with similar structures have been investigated for their roles in biological signaling and therapeutic potential, making this compound a subject of interest in drug discovery research.

As a compound that bridges organic chemistry and pharmacology, ethyl 2,4-dimethyl-5-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrole-3-carboxylate exemplifies the intricate relationship between structure and function in chemical compounds. Its exploration could pave the way for breakthrough innovations in treating various diseases.

Synonyms
15966-93-5
SU5408
ethyl 2,4-dimethyl-5-[(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrole-3-carboxylate
IN1018
PMUJUSJUVIXDQC-UHFFFAOYSA-N
SU-5408
DTXSID30274474
BCP29247
SU 5408; SU5408; VEGFR2 Kinase Inhibitor I
(2,4-Dimethyl-3-ethoxycarbonylpyrrol-5-yl methylene]-2-indolinone
3-[(2,4-dimethyl-3-ethoxycarbonylpyrrol-5-yl) methylene]-2-indolinone
3-[(2,4-Dimethyl-3-ethoxycarbonylpyrrol-5-yl)methylene]-2-indolinone
ethyl 2,4-dimethyl-5-{[(3Z)-2-oxo-1H-indol-3-ylidene]methyl}-1H-pyrrole-3-carboxylate