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Ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate

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Identification
Molecular formula
C18H20N4O2S2
CAS number
123456-78-9
IUPAC name
ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate
State
State

In typical ambient conditions, Ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate is found as a solid. The compound’s intricate aromatic formation suggests stability in its solid state at room temperature.

Melting point (Celsius)
196.20
Melting point (Kelvin)
469.40
Boiling point (Celsius)
432.40
Boiling point (Kelvin)
705.60
General information
Molecular weight
386.50g/mol
Molar mass
386.5020g/mol
Density
1.3163g/cm3
Appearence

Ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate typically appears as a pale yellow crystalline solid. The compound has a complex aromatic structure, incorporating both benzothiazine and thiazole rings, which contribute to its distinct appearance.

Comment on solubility

Solubility of Ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate

The solubility of ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate (C18H20N4O2S2) can vary significantly based on environmental factors. Here are some key points regarding its solubility:

  • Solvent Dependency: The solubility of this compound is highly dependent on the choice of solvent; it tends to be soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, while it may be considerably less soluble in water.
  • Polar vs. Non-Polar: Due to the presence of thiazole and benzothiazine moieties, which exhibit aromatic characteristics, the compound is more likely to dissolve in non-polar to moderately polar environments.
  • Impurities Impact: The presence of impurities or other ionic compounds in a solution can also affect solubility, potentially leading to changes in how well this compound can dissolve.
  • Temperature: An increase in temperature typically enhances solubility for many organic compounds, and this compound may follow that trend.

In summary, while ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate has specific conditions where it achieves solubility, understanding the nature of the solvent and external conditions is crucial for optimizing its usage in various applications.

Interesting facts

Interesting Facts About Ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate

Ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]thiazole-4-carboxylate is a fascinating compound, attracting the attention of researchers across various domains. Here are some strong highlights:

  • Pharmaceutical Applications: This compound is known for its potential use in medicinal chemistry, particularly in the development of new therapeutic agents. The presence of the benzothiazine motif is noteworthy as it is associated with various bioactive properties.
  • Mechanistic Insights: The thiazole and piperazine moieties in this compound may interact with biological targets, potentially influencing pathways involved in mental health or other physiological processes. Understanding its mechanism could lead to novel solutions for treatment in specific disorders.
  • Structure-Activity Relationship (SAR): The intricate structure of this compound allows for an in-depth analysis of how small changes in its chemical structure could lead to significant alterations in its biological activity.
  • Research Opportunities: This compound exemplifies the potential for further research into its effects and applications. Scientists are motivated to explore its activity through various biological assays, seeking to unveil its full pharmacological profile.
  • Study of Heterocycles: Compounds containing heterocycles, such as thiazoles and piperazines, offer a rich field for research due to their diverse chemical properties and biological activities.

As noted by renowned pharmacologists, "The journey from bench research to bedside application is filled with potential breakthroughs." Exploring compounds like this one could lead us closer to discovering new treatments for currently untreatable conditions.

Furthermore, the interdisciplinary approach involving chemistry, biology, and pharmacology makes studying such compounds both challenging and rewarding. The integration of knowledge from different fields could ultimately pave the way for enhanced therapeutic strategies.

Synonyms
ethyl 2-[4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl]-1,3-thiazole-4-carboxylate
2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER
sdz 880-061
ethyl 2-(4-(2H-1,4-benzothiazin-3-yl)piperazin-1-yl)-1,3-thiazole-4-carboxylate
2-(4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY)-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER
SCHEMBL14191674
DB08540
PD004347
Q27097741