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Bromophenol Blue

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Identification
Molecular formula
C19H10Br4O5S
CAS number
115-39-9
IUPAC name
disodium;2-hydroxy-5-[4,5,6,7-tetrabromo-1-(4-hydroxy-3-sulfonato-phenyl)-3-oxo-isobenzofuran-1-yl]benzenesulfonate
State
State

At room temperature, Bromophenol Blue is a solid. It is used as a pH indicator and is known to transition from yellow to blue over a pH range of 3.0 to 4.6.

Melting point (Celsius)
279.00
Melting point (Kelvin)
552.15
Boiling point (Celsius)
990.00
Boiling point (Kelvin)
1 263.15
General information
Molecular weight
669.96g/mol
Molar mass
669.9600g/mol
Density
0.6893g/cm3
Appearence

Bromophenol Blue appears as a pinkish to purple crystalline powder.

Comment on solubility

Solubility of Disodium 2-Hydroxy-5-[4,5,6,7-tetrabromo-1-(4-hydroxy-3-sulfonato-phenyl)-3-oxo-isobenzofuran-1-yl]benzenesulfonate

The solubility profile of the compound disodium 2-hydroxy-5-[4,5,6,7-tetrabromo-1-(4-hydroxy-3-sulfonato-phenyl)-3-oxo-isobenzofuran-1-yl]benzenesulfonate (C19H10Br4O5S) is influenced by several key factors:

  • Ionic nature: As a disodium compound, it is likely to exhibit significant solubility in polar solvents, especially water, due to the presence of charged ions that can interact favorably with water molecules.
  • Functional groups: The sulfonate groups enhance water solubility, allowing for greater interaction with aqueous environments, while the presence of bromine atoms may impact solubility through hydrophobic interactions.
  • Temperature effect: Generally, the solubility of substances can increase with temperature; thus, increasing the temperature may facilitate the dissolution of this compound in water.

Further evaluation in various solvents may yield additional insights into the solubility characteristics. As evidenced by similar compounds, one might find that:

  • In non-polar solvents, the solubility might be significantly reduced due to the hydrophilic nature of the sulfonate group.
  • In mixed solvents, like water-alcohol mixtures, you may observe a varied solubility profile driven by the interplay of solvent properties.

In conclusion, the solubility of this compound is primarily dictated by its ionic structure and the presence of functional groups conducive to interaction with polar solvents. Assessing its solubility will be crucial for understanding its chemical behavior and potential applications.

Interesting facts

Interesting Facts about Disodium 2-Hydroxy-5-[4,5,6,7-Tetrabromo-1-(4-Hydroxy-3-sulfonato-phenyl)-3-oxo-isobenzofuran-1-yl]benzenesulfonate

Disodium 2-hydroxy-5-[4,5,6,7-tetrabromo-1-(4-hydroxy-3-sulfonato-phenyl)-3-oxo-isobenzofuran-1-yl]benzenesulfonate is a complex chemical compound that has garnered attention in various fields for its unique structure and properties. Here are some fascinating aspects of this compound:

  • Biological Activity: This compound is known for its significant biological activities, including antibacterial and antifungal properties. Such capabilities make it valuable in pharmaceuticals and agricultural applications.
  • Colorant Applications: Due to the presence of bromine atoms, this compound can be used as a colorant, contributing to intermediary applications in dye and pigment production.
  • Research and Development: The intricate structure of this compound has prompted research into new synthetic pathways which could lead to innovative materials in nanotechnology and organic electronics.
  • Environmental Impact: With the increasing concern over environmental pollution, understanding how such brominated compounds interact with ecosystems is crucial, raising questions about their biodegradability and overall environmental impact.
  • Structure-Activity Relationship: This compound serves as a critical example in the study of structure-activity relationships (SAR) in medicinal chemistry, highlighting how modifications in molecular structure can dramatically affect biological efficacy.

In summary, disodium 2-hydroxy-5-[4,5,6,7-tetrabromo-1-(4-hydroxy-3-sulfonato-phenyl)-3-oxo-isobenzofuran-1-yl]benzenesulfonate is not just a fascinating molecule due to its intricate structure, but it also plays important roles in science and applications, stirring curiosity among chemists and researchers alike.

Synonyms
Bromosulfalein
bromsulphthalein
71-67-0
Bromosulfophthalein
Hepatestabrome
Hepatosulfalein
Hepartest
BSP sodium
Sodium bromsulphalein
Bromotaleina
Bromsulphalein
Bromthalein
Bromsulfan
Sodium bromsulphthalein
Bromosulphthalein
Bromsulfophthalein
BSF simes
Bromsulfalein
Sodium bromosulfalein
Bromsulphalein R sodium
SODIUM SULFOBROMOPHTHALEIN
Sulfobromophthalein disodium salt
Sodium bromosulfophthalein
Sodium sulphobromophthalein
Sulphobromophthalein sodium
Disodium bromosulfophthalein
Tetrabromophenolsulfophthalein
Sodium phenol tetrabromophthalein
Sulfobromopthalein sodium
Disodium phenoltetrabromophthalein sulfonate
62E5JU30OV
SULFOBROMPHTHALEIN SODIUM
DTXSID9023621
CHEBI:63827
4,5,6,7-Tetrabromo-3',3''-disulfophenolphthalein disodium salt
Sulfobromophthalein sodium (JP17)
Benzenesulfonic acid, 3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis(6-hydroxy-, disodium salt
Benzenesulfonic acid, 3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxy-, disodium salt
Disodium 6,6'-dihydroxy-3,3'-(4,5,6,7-tetrabromo-1,3-dihydro-3-oxoisobenzofuran-1-ylidene)dibenzenesulphonate
Bromsulfthalein
Hepartestabrome
Brom-tetragnost
Phenolphthalein, 4,5,6,7-tetrabromo-3',3''-disulfo-, disodium salt
DTXCID503621
CAS-71-67-0
BSF
disodium 3,3'-(4,5,6,7-tetrabromo-3-oxo-1,3-dihydro-2-benzofuran-1,1-diyl)bis(6-hydroxybenzenesulfonate)
CBSP
NCGC00159391-02
NCGC00159391-03
UNII-62E5JU30OV
Bromtetragnost
HSDB 2183
disodium 2-hydroxy-5-[4,5,6,7-tetrabromo-1-(4-hydroxy-3-sulfonatophenyl)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]benzene-1-sulfonate
EINECS 200-761-0
BROMOSULPHALEIN
Sulfobromophthalein sodium [USP:JAN]
bromsulphthalein sodium
bromosulfophthalein sodium
[3H]BSP
TETRABROMOSULFOPHTHALEIN
SCHEMBL487073
[3H]-BSP
CHEMBL453904
GTPL4505
GTPL4506
bromosulfophthalein disodium salt
phenoltetrabromophthaleinsulfonate
Tox21_111628
AKOS024373601
Tox21_111628_1
5,5'-(4,5,6,7-Tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis(2-hydroxybenzenesulfonic acid) disodium salt
DA-58185
NS00079056
D02210
G12059
Q926998
4,5,6,7-Tetrabromo-3',3'-disulfophenolphthalein disodium salt
4,5,6,7Tetrabromo3',3''disulfophenolphthalein disodium salt
Phenolphthalein, 4,5,6,7tetrabromo3',3''disulfo, disodium salt
3,3'(4,5,6,7Tetrabromo3oxo1(3H)isobenzofuranylidene)bis disodium salt
5,5'-(4,5,6,7-TETRABROMO-3-OXO-1(3H)-ISOBENZOFURANYLID ENE)BIS
5,5'(4,5,6,7Tetrabromo3oxo1(3H)isobenzofuranylidene)bis(2hydroxybenzenesulfonic acid) disodium salt
626-376-1
Benzenesulfonic acid, 3,3'(4,5,6,7tetrabromo3oxo1(3H)isobenzofuranylidene)bis(6hydroxy, disodium salt
Benzenesulfonic Acid, 3,3'-(4,5,6,7-Tetrabromo-3-Oxo-1(3H)-Isobenzofuranylidene)Bis(6-Hydroxy)-, Disodium Salt
Disodium 5,5'-(4,5,6,7-tetrabromo-3-oxo-1,3-dihydroisobenzofuran-1,1-diyl)bis(2-hydroxybenzenesulfonate)
Disodium 6,6'dihydroxy3,3'(4,5,6,7tetrabromo1,3dihydro3oxoisobenzofuran1ylidene)dibenzenesulphonate