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Clonidine

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Identification
Molecular formula
C18H18ClN2O
CAS number
4205-90-7
IUPAC name
dimethyl-[2-(11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl]ammonium;chloride
State
State

At room temperature, Clonidine hydrochloride is solid. It is stable under standard conditions and should be stored in a tightly sealed container to maintain its integrity.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
248.13g/mol
Molar mass
248.1250g/mol
Density
1.3120g/cm3
Appearence

Clonidine hydrochloride typically appears as a white or off-white, crystalline powder. It is known for its stability and purity when maintained properly. The compound is often used in its solid form for pharmaceutical applications.

Comment on solubility

Solubility of Dimethyl-[2-(11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl]ammonium;chloride

The solubility of dimethyl-[2-(11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl]ammonium;chloride can be quite intriguing due to its complex structure. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of this compound is significantly influenced by the choice of solvent. Generally, it tends to be soluble in polar solvents such as water and methanol due to the ionic nature of the chloride part of the compound.
  • Temperature Effects: As with many ionic compounds, increasing the temperature may enhance solubility. Thus, a higher temperature typically leads to an increase in solubility.
  • pH Sensitivity: The solubility can be affected by the pH of the solution, where differences in protonation states may lead to variations in solubility.
  • Complex Formation: It may also form complexes with other molecules, which can either increase or decrease its overall solubility depending on the specific interactions involved.

Overall, while the compound may have certain solubility properties in aqueous conditions, understanding the specific context of solubility requires studying interactions with various solvents and environmental factors. As a general takeaway, the solubility characteristics can be summarized as:

  • Often soluble in polar solvents
  • Sensitivity to temperature and pH changes
  • Possible complexation affecting overall solubility

This complex interplay of factors makes the solubility of dimethyl-[2-(11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl]ammonium;chloride an interesting subject for further exploration.

Interesting facts

Dimethyl-[2-(11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl]ammonium Chloride

Dimethyl-[2-(11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl]ammonium chloride is a fascinating compound with a structure that draws significant attention in the field of medicinal chemistry. This compound belongs to the class of benzodiazepines, which are known for their psychoactive properties and are widely used in pharmacology.

Key Characteristics:

  • Benzodiazepine Framework: The presence of a benzodiazepine structure gives this compound the potential to interact with the GABAA receptor, leading to anxiolytic (anxiety-reducing) effects.
  • Dimethylammonium Group: The dimethylammonium moiety may contribute to increased solubility and enhanced biological activity.
  • Oxo Group: The inclusion of the 6-oxo group may affect the reactivity and chemical stability of the compound, making it suitable for various synthetic routes.

Applications and Research:

This compound is of particular interest in the development of new therapeutic agents. Researchers are exploring the following areas:

  • Psychoactive Studies: Its potential use in treating anxiety disorders due to the effects of benzodiazepines.
  • Synthetic Pathways: The compound presents interesting opportunities for synthesis, which can help in understanding structure-activity relationships within the benzodiazepine class.
  • Neuropharmacology: Investigating how variations in structure affect neurochemical interactions and can lead to novel drug candidates.

As we continue to delve into the complexities of such compounds, it becomes evident that dimethyl-[2-(11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl]ammonium chloride not only serves as a valuable research tool but also paves the way for future innovations in drug development. The study of this compound exemplifies the intricate link between chemistry and pharmacology, motivating scientists to explore and unlock new therapeutic possibilities.