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Butyl 2-[3-(trifluoromethyl)anilino]benzoate

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Identification
Molecular formula
C18H17F3NO2
CAS number
18762-75-5
IUPAC name
butyl 2-[3-(trifluoromethyl)anilino]benzoate
State
State
At room temperature, Butyl 2-[3-(trifluoromethyl)anilino]benzoate is often found as a liquid or a viscous liquid depending on the conditions.
Melting point (Celsius)
42.00
Melting point (Kelvin)
315.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
335.33g/mol
Molar mass
335.3210g/mol
Density
1.2660g/cm3
Appearence
Butyl 2-[3-(trifluoromethyl)anilino]benzoate typically appears as a colorless to pale yellow liquid. It may have a faint, characteristic odor.
Comment on solubility

Solubility of Butyl 2-[3-(trifluoromethyl)anilino]benzoate

Butyl 2-[3-(trifluoromethyl)anilino]benzoate (C18H17F3NO2) exhibits intriguing solubility characteristics that are influenced by its chemical structure. Understanding the solubility of this compound is vital for its application in various chemical processes.

Key Factors Affecting Solubility

The solubility of butyl 2-[3-(trifluoromethyl)anilino]benzoate can be summarized with the following considerations:

  • Polarity: The presence of the trifluoromethyl group contributes to overall polarity which may hinder solubility in non-polar solvents.
  • Hydrophobic interactions: The butyl group enhances hydrophobic interactions, potentially increasing solubility in organic solvents.
  • Hydrogen bonding: The compound's capacity to form hydrogen bonds can enhance solubility in polar solvents such as alcohols.

General Insight on Solubility

In practical terms, butyl 2-[3-(trifluoromethyl)anilino]benzoate is expected to have:

  • Moderate to good solubility in organic solvents (e.g., ethyl acetate, chloroform).
  • Limited solubility in water due to the non-polar characteristics of the butyl group.
  • Increased solubility in polar aprotic solvents due to the potential for solvent-solute interactions.

As with many compounds, the solubility can be influenced by temperature and the presence of other solutes. Therefore, it is crucial to evaluate solubility under various conditions to predict behavior in practical applications.

Interesting facts

Interesting Facts about Butyl 2-[3-(Trifluoromethyl)anilino]benzoate

Butyl 2-[3-(trifluoromethyl)anilino]benzoate is a fascinating compound that showcases the intricate balance of organic chemistry and its applications. Here are several engaging points about this compound:

  • Structure and Functionality: This compound features a complex structure incorporating a butyl group, which contributes to its hydrophobic properties, alongside a trifluoromethyl group, known for its strong electron-withdrawing capabilities.
  • Applications: The incorporation of the trifluoromethyl group often leads to enhanced biological activity, making this compound potentially useful in pharmaceuticals and agrochemicals. Its unique structure might be utilized in materials science for developing new polymers.
  • Fluorinated Compounds: Compounds containing fluorine atoms, like the trifluoromethyl group in this molecule, are gaining significant attention in medicinal chemistry due to their lipophilicity and metabolic stability. This can lead to improved drug delivery systems.
  • Environmental Considerations: While fluorinated compounds can enhance performance in many applications, they can also pose environmental challenges. Understanding their degradation pathways is crucial, as some can persist in the environment.
  • Research Opportunities: The synthesis and study of butyl 2-[3-(trifluoromethyl)anilino]benzoate can open new avenues in research. The compound serves as a prime candidate for exploring structure-activity relationships in drug design.

In summary, butyl 2-[3-(trifluoromethyl)anilino]benzoate exemplifies the beauty and utility of organic compounds in modern chemistry. Its intricate interplay between structure and functionality highlights its importance in various scientific fields.

Synonyms
ufenamate
67330-25-0
Butyl flufenamate
Butyl 2-((3-(trifluoromethyl)phenyl)amino)benzoate
Combec
Flufenamic acid butyl ester
Ufenamato
Ufenamatum [Latin]
fenazol
Ufenamato [Spanish]
Ufenamatum
Ufenamate [INN:JAN]
8Z7O7C1SLZ
butyl 2-[3-(trifluoromethyl)anilino]benzoate
HF 264
Combec (TN)
BRN 2768727
UFENAMATE [INN]
UFENAMATE [JAN]
UFENAMATE [MART.]
Butyl o-((m-(trifluoromethyl)phenyl)amino)benzoate
UFENAMATE [WHO-DD]
DTXSID30867269
EC 614-050-1
Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, butyl ester
N-(alpha,alpha,alpha-Trifluoro-m-tolyl)anthranilic acid butyl ester
Anthranilic acid, N-(alpha,alpha,alpha-trifluoro-m-tolyl)-, butyl ester
Ufenamatum (Latin)
Butyl N-(alpha,alpha,alpha-trifluoro-m-tolyl)anthranilate
FLUFENAMIC ACID BUTYL ESTER [MI]
Flufenamic acid butyl ester;Butyl flufenamate
Butyl N-(3-Trifluoromethylphenyl)anthranilate
UFENAMATE (MART.)
BENZOIC ACID, 2-((3-(TRIFLUOROMETHYL)PHENYL)AMINO)-, BUTYL ESTER
N-(3-Trifluoromethylphenyl)anthranilic Acid Butyl Ester
Butyl 2-[[3-(Trifluoromethyl)phenyl]-amino]benzoate (Butyl Flufenamate)
BUTYL N-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)ANTHRANILATE
Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate
UNII-8Z7O7C1SLZ
Butylflufenamat
MFCD00866001
Ufenamate (JAN/INN)
SCHEMBL36095
Butyl2-((3-(trifluoromethyl)phenyl)amino)benzoate
CHEMBL2105605
CHEBI:32276
DTXCID10815465
BCP20289
s5261
AKOS015843205
CCG-267880
CS-5536
FF58677
AC-22582
AS-35175
DA-58864
HY-100009
B5391
ETOFENAMATE IMPURITY B [EP IMPURITY]
NS00007942
D01823
n-Butyl N-(3-trifluoromethylphenyl)anthranilate
Butyl 2-[[3-(trifluoromethyl)phenyl]amino]benzoat
Q7877498
BRD-K84173274-001-01-6
2-[[3-(Trifluoromethyl)phenyl]amino]benzoic Acid Butyl Ester
Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-,butyl ester
614-050-1
Butyl 2-[[3-(Trifluoromethyl)phenyl]-amino]benzoate; Etofenamate Imp. B (EP); Butyl Flufenamate; Etofenamate Impurity B