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Bromoform

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Identification
Molecular formula
CHBr3
CAS number
75-25-2
IUPAC name
bromoform
State
State

In its pure form, bromoform is a liquid at room temperature. It is not soluble in water, but it is moderately soluble in alcohol and very soluble in ether and chloroform.

Melting point (Celsius)
8.50
Melting point (Kelvin)
281.65
Boiling point (Celsius)
149.36
Boiling point (Kelvin)
422.51
General information
Molecular weight
252.73g/mol
Molar mass
252.7310g/mol
Density
2.8900g/cm3
Appearence

Bromoform is a colorless liquid at room temperature, although it may appear yellowish due to impurities. It has a sweet, chloroform-like aroma and is highly refractive, making it appear oily or syrup-like.

Comment on solubility

Solubility of Bromoform (CHBr3)

Bromoform, or tribromomethane, exhibits interesting solubility characteristics that are essential to understanding its behavior in various environments. Below are key points regarding the solubility of bromoform:

  • Solvent Shell: Bromoform is known for its relatively low solubility in water, making it hydrophobic. This limited solubility can be attributed to the strong carbon-bromine bonds and the molecule's overall nonpolar nature.
  • Organic Solvents: Conversely, bromoform demonstrates a high solubility in many organic solvents such as chloroform, benzene, and ethyl alcohol. This characteristic makes it valuable in various chemical applications.
  • Environment Interaction: Due to its hydrophobicity, bromoform tends to accumulate in fatty tissues and may have implications for aquatic life when released into the environment.

The solubility of bromoform showcases the diverse interactions that this compound can engage in with different solvents. Understanding these properties is crucial for its effective application and management in both research and industrial contexts.

Interesting facts

Interesting Facts About Bromoform

Bromoform, a fascinating compound with the formula CHBr3, is part of the haloform family and is composed of one carbon atom, three bromine atoms, and one hydrogen atom. This intriguing compound has various significant applications and properties that make it noteworthy in the field of chemistry.

1. Historical Significance

Bromoform has a rich history and was once used as a solvent in organic synthesis. Its rarity has made it a subject of interest for those studying halogenated compounds.

2. Natural Occurrence

It is interesting to note that bromoform can be found in trace amounts in nature, primarily within certain marine algae. This points to its role in biological processes and potential environmental relevance.

3. Chemical Reactions

  • Reactivity: Bromoform reacts with strong bases and can undergo dehydrobromination, leading to useful synthetic pathways for other organic compounds.
  • Formation: It can also be synthesized through the reaction of methane with bromine.

4. Applications

Bromoform's primary applications include:

  • Solvent: It is used as a solvent in various organic reactions, particularly in the extraction of certain compounds.
  • Analytical Chemistry: Bromoform serves in analytical chemistry as a reference compound due to its unique spectral properties.
  • Density Gradient Centrifugation: Its high density allows it to be used in the separation of biological samples.

5. Environmental and Health Considerations

Although bromoform has useful properties, it is essential to handle it with care. It can pose health risks, including potential toxicity and environmental concerns associated with halogenated organics. As with many chemicals, it is crucial to consider the precautionary principles when working with bromoform.

In summary, bromoform is a remarkable compound with a variety of intriguing applications and historical significance, illustrating the complexity and utility of halogenated substances in chemistry.

Synonyms
Bromoform
tribromomethane
75-25-2
Methane, tribromo-
Tribrommethan
Methenyl tribromide
Methyl tribromide
Bromoforme
Bromoformio
Tribrommethaan
Tribromometan
CHBr3
Bromoforme [French]
Bromoformio [Italian]
NCI-C55130
Tribrommethaan [Dutch]
Tribrommethan [German]
Tribromometan [Italian]
RCRA waste number U225
TUT9J99IMU
NSC 8019
DTXSID1021374
CHEBI:38682
BROMOFORM [MI]
NSC-8019
BROMOFORM [HSDB]
BROMOFORM [IARC]
MFCD00000128
BROMOFORM [WHO-DD]
DTXCID401374
4471-18-5
NSC8019
Bromoform - Stabilized with ethanol
UN 2515
Tribrommethan (German)
BROMOFORM (IARC)
BROMOFORME (FRENCH)
BROMOFORMIO (ITALIAN)
TRIBROMMETHAAN (DUTCH)
TRIBROMOMETAN (ITALIAN)
CCRIS 98
Bromoform [USP]
MBR
HSDB 2517
EINECS 200-854-6
UNII-TUT9J99IMU
UN2515
RCRA waste no. U225
BROMOFORM (13C)
BRN 1731048
Tribromomethane; Bromoform; Methenyl tribromide; NSC 8019
bromo form
AI3-28587
methane, tribromo
Tri bromo methane
Tribromomethane; methyl tribromide
methylene tribromide
TRIBROM METHAN
FORMYL TRIBROMIDE
WLN: EYEE
Bromoform, technical grade
Bromoform (ACGIH:OSHA)
SCHEMBL18691
4-01-00-00082 (Beilstein Handbook Reference)
BIDD:ER0622
Bromoform, puriss., 97.0%
CHEMBL345248
TRIBROM METHAN (GERMAN)
Bromoform [UN2515] [Poison]
BCP10566
Bromoform (stabilized with Ethanol)
Tox21_200189
R-20B3
Bromoform 100 microg/mL in Methanol
Bromoform, 96%, stab. with ethanol
AKOS009031540
AT27291
Bromoform 5000 microg/mL in Methanol
DB03054
CAS-75-25-2
Bromoform, puriss., >=99.0% (GC)
MSK000954-1000M
NCGC00091318-01
NCGC00091318-02
NCGC00257743-01
BP-21414
FB163767
Tribromomethane (stabilized with Ethanol)
Tribromomethane 100 microg/mL in Methanol
Bromoform Solution in Methanol, 1000ug/mL
B0806
NS00002299
S0653
T0348
EN300-19388
Bromoform, amylene stabilized, analytical standard
Q409799
Bromoform, contains 1-3% ethanol as stabilizer, 96%
F0001-1896
Bromoform - contains 60-120ppm 2-Methyl-2-butene as stabilizer
BROMOFORM (CONTAINS 60-120PPM 2-METHYL-2-BUTENE AS STABILIZER)
Bromoform, contains 60-120 ppm 2-methyl-2-butene as stabilizer, 99%
200-854-6