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Bis(acetoxymethoxy)phosphoryl-(2-naphthyl)methoxy)methyl acetate

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Identification
Molecular formula
C20H21O10P
CAS number
216351-09-4
IUPAC name
[bis(acetoxymethoxy)phosphoryl-(2-naphthyl)methoxy]methyl acetate
State
State

At room temperature, this compound is a liquid, which is uncommon for many organophosphorus compounds. Its oily nature makes it distinct in handling and applications.

Melting point (Celsius)
-25.00
Melting point (Kelvin)
248.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
408.34g/mol
Molar mass
408.3410g/mol
Density
1.2500g/cm3
Appearence

The compound is typically presented as a colorless to pale yellow liquid. It may be transparent and it is often described as having an oily texture.

Comment on solubility

Solubility of [bis(acetoxymethoxy)phosphoryl-(2-naphthyl)methoxy]methyl acetate

The solubility of the compound [bis(acetoxymethoxy)phosphoryl-(2-naphthyl)methoxy]methyl acetate (C20H21O10P) can be attributed to its complex molecular structure and functional groups. Understanding its solubility characteristics is vital for various applications.

Solubility Characteristics:

  • Polar Functional Groups: The presence of acetoxy and methoxy groups contributes to polar interactions, enhancing solubility in polar solvents.
  • Non-Polar Components: The 2-naphthyl moiety introduces non-polar characteristics, which can hinder solubility in highly polar environments.
  • Solvent Dependence: This compound is expected to show good solubility in organic solvents like acetone and ethyl acetate while exhibiting limited solubility in water.
  • Intermolecular Interactions: The balance between polar and non-polar regions plays a critical role in determining solubility behavior.

In summary, the solubility of this compound is influenced by a combination of its polar functional groups and non-polar aromatic structure, making it soluble in specific organic solvents while remaining less soluble in aqueous solutions. Consequently, for practical applications, it is important to consider the solvent choice to maximize solubility and reactivity.

Interesting facts

Interesting Facts about [bis(acetoxymethoxy)phosphoryl-(2-naphthyl)methoxy]methyl acetate

The compound bis(acetoxymethoxy)phosphoryl-(2-naphthyl)methoxy]methyl acetate, often shortened to its component parts, is a fascinating substance that exemplifies the complexity of organophosphorus chemistry. Here are some noteworthy aspects:

  • Functional Versatility: This compound showcases a rich array of functional groups, enabling a wide range of chemical reactivity. This versatility is significant in various fields, including medicinal chemistry and material science.
  • Phosphorus in Chemistry: The phosphorus atom in this nomenclature illustrates its crucial role in biological systems, particularly in DNA and RNA structures. Organophosphorus compounds are vital in agriculture as pesticides and herbicides, demonstrating their importance in food production.
  • Applications: The presence of methoxy and acetate groups suggests potential applications in drug delivery systems. Such compounds can be engineered to improve solubility and bioavailability of pharmaceuticals, leading to more effective therapeutic agents.
  • Synthetic Pathways: The synthesis of this compound involves sophisticated organic transformations. Understanding these pathways can offer insights into greener and more efficient chemical manufacturing processes, such as using less harmful solvents and reagents.
  • Biological Relevance: Research into compounds like this one is crucial, as it leads to a deeper understanding of how phosphorus-containing compounds interact in biological systems, potentially leading to new drug discoveries.
  • Structure-Activity Relationship (SAR): Investigating the relationship between its structure and biological activity may provide key insights into designing more effective and selective compounds for therapeutic use.

In summary, bis(acetoxymethoxy)phosphoryl-(2-naphthyl)methoxy]methyl acetate is not just a chemical structure, but a harbinger of future innovations in chemistry and biochemistry. As scientists continue to unravel its mysteries, this compound may hold the key to advancements in several vital scientific domains.

Synonyms
HNMPA-(AM)3
120944-03-8
HNMPA-(AM(3))
CHEBI:75391
[bis(acetyloxymethoxy)phosphoryl-naphthalen-2-ylmethoxy]methyl acetate
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester
3-[(acetyloxy)methoxy]-4-(naphthalen-2-yl)-3-oxido-8-oxo-2,5,7-trioxa-3lambda(5)-phosphanon-1-yl acetate
Bio1_000738
Hydroxy-2-naphthalenylmethylphosphonic Acid Trisacetoxymethyl Ester
3-((acetyloxy)methoxy)-4-(naphthalen-2-yl)-3-oxido-8-oxo-2,5,7-trioxa-3lambda(5)-phosphanon-1-yl acetate
MolMap_000027
CBiol_001963
BSPBio_001119
KBioGR_000459
KBioSS_000459
CHEMBL1435748
BCBcMAP01_000216
KBio2_000459
KBio2_003027
KBio2_005595
KBio3_000857
KBio3_000858
Bio1_000249
Bio1_001227
Bio2_000390
Bio2_000870
DTXSID101017621
HMS1362G21
HMS1792G21
HMS1990G21
HMS3403G21
AKOS040755349
IDI1_002145
NCGC00163452-01
NCGC00163452-02
HY-124097
CS-0084188
Q27145268
((((Acetoxymethoxy)(naphthalen-2-yl)methyl)phosphoryl)bis(oxy))bis(methylene) diacetate