Boc-Val-Pro-Val-OH | Solubility of Things

Identification

Molecular formula

C₂₇H₃₆N₄O₆

CAS number

5683-38-1

IUPAC name

benzyl N-[1-[3-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamate

State

At room temperature, this compound is typically a solid.

Melting point (Celsius)

112.00

Melting point (Kelvin)

385.15

Boiling point (Celsius)

-1.00

Boiling point (Kelvin)

-1.00

General information

Molecular weight

488.60g/mol

Molar mass

488.5690g/mol

Density

1.2500g/cm³

Appearence

The compound appears as a white to off-white powder or crystalline substance.

Comment on solubility

Solubility of Benzyl N-[1-[3-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamate

The solubility of the compound benzyl N-[1-[3-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamate, with a chemical formula of C₂₇H₃₆N₄O₆, is influenced by various factors due to its complex structure. As a carbamate derivative, its solubility can generally exhibit a range of behaviors depending on the solvent:

Polar Solvents: The presence of amino and carbonyl groups suggests some solubility in polar solvents, such as water and alcohols.
Non-Polar Solvents: The significant hydrocarbon (benzyl) moieties indicate enhanced solubility in non-polar organic solvents like chloroform and dichloromethane.
pH Dependence: Solubility can also vary with pH, as the ionization of amine groups may enhance aqueous solubility in basic conditions.

Overall, the solubility profile of this compound is likely to be:

Moderate to high in polar solvents due to functional groups.
Higher in non-polar solvents due to hydrophobic interactions.
Variable with changes in pH, which can affect the ionization state.

To summarize, the complex nature of benzyl N-[1-[3-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamate leads to interesting solubility behavior that is sensitive to the solvent environment and pH levels.

Interesting facts

Interesting Facts about Benzyl N-[1-[3-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamate

Benzyl N-[1-[3-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamate is a fascinating compound notable for its potential implications in the field of medicinal chemistry. Here are some intriguing points to consider:

Complex Structure: The compound features a multistep synthesis pathway, showcasing intricate organic chemistry methodologies. Its architecture includes multiple functional groups which enable diverse interactions.
Potential Therapeutic Uses: Due to its structural components, this compound could exhibit biological activities, particularly in cancer research and drug delivery systems.
Carbamate Functionality: The presence of the carbamate group may enhance the compound's stability and solubility while contributing to its pharmacokinetic properties.
Harnessing the Pyrrolidine Ring: The inclusion of a pyrrolidine ring is noteworthy as it often plays a crucial role in various biological mechanisms, including enzymatic functions and receptor binding.
Peptidomimetic Properties: It mimics peptide structures, potentially aiding in drug design for therapeutic agents aimed at targeting specific biochemical pathways.

As you study such compounds, remember the saying: "Chemistry is the art of transformation." This compound serves as a prime example of how chemical transformations can yield materials with innovative potential in the pharmaceutical sphere.

In conclusion, Benzyl N-[1-[3-[[2-(benzyloxycarbonylamino)-4-methyl-pentanoyl]amino]-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamate encapsulates not only the complexity of chemical synthesis but also the promising prospects for future scientific exploration.

Synonyms

PD042093