Interesting facts
Interesting Facts about Adamantan-1-amine
Adamantan-1-amine, a fascinating compound derived from adamantane, has drawn attention in various scientific fields due to its unique structure and properties. Here are some intriguing aspects:
- Structural Family: Adamantan-1-amine belongs to the class of amines. Its structure is based on the rigid, cage-like hydrocarbon framework of adamantane, which is notable for its high stability.
- Biological Relevance: Research indicates that derivatives of adamantan-1-amine may have potential applications in medicinal chemistry, particularly in the development of antiviral drugs. The compound has shown promise in inhibiting viral replication.
- Physicochemical Properties: The rigidity of its adamantane structure contributes to its interesting physicochemical properties, making it a subject of study in material sciences. Its three-dimensional structure enhances its potential for unique interactions.
- Applications in Medicine: Aside from antiviral applications, compounds derived from adamantan-1-amine are being explored for potential neuroprotective effects, which could provide avenues for treating neurodegenerative disorders.
- Research and Innovation: The synthesis of adamantan-1-amine has spurred innovative synthetic approaches within organic chemistry, showcasing how modifying existing frameworks can yield compounds with diverse properties.
- Enhanced Solubility: Modifications to adamantan derivatives, including adding amine groups, can influence their solubility and biological activity, making this compound a focal point for enhancing drug delivery systems.
In summation, adamantan-1-amine is not just a simple compound; it is a chemical building block with enormous potential in various fields including pharmacology, material science, and beyond. Researchers continue to uncover its secrets, making it a vibrant topic in contemporary chemistry.
Synonyms
amantadine
1-Adamantanamine
768-94-5
adamantan-1-amine
1-Adamantylamine
1-Aminoadamantane
Adamantanamine
Adamantylamine
Aminoadamantane
Amantidine
Symmetrel
Pk-merz
Adamantamine
Amantadina
Symadine
1-Adamantamine
Amantadinum
adamantan-1-ylamine
Gocovri
Amantadinum [INN-Latin]
Amantadina [INN-Spanish]
MFCD00074732
1-Aminotricyclo(3.3.1.1(sup 3,7))decane
NSC 341865
HSDB 3202
TCMDC-125869
1-adamantaneamine
Tricyclo(3.3.1.1(3,7))-decan-1-amine
EINECS 212-201-2
UNII-BF4C9Z1J53
Amantadine (INN)
Tricyclo(3.3.1.1(sup 3.7))decan-1-amine
NSC-341865
BRN 2204333
BF4C9Z1J53
CHEBI:2618
Tricyclo(3.3.1.13,7)decan-1-amine
DTXSID8022117
tricyclo[3.3.1.1~3,7~]decan-1-amine
1 Aminoadamantane
Tricyclo[3.3.1.1(3,7)]decan-1-amine
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine
CHEMBL660
DTXCID502117
EC 212-201-2
NSC341865
(3s,5s,7s)-Tricyclo[3.3.1.1~3,7~]decan-1-Amine
768-94-5 (FREE BASE)
NCGC00015036-03
Tricyclo[3.3.1.13,7]decan-1-amine
Tricyclo[3.3.1.13,7]decane-1-amine
AMANTADINE [INN]
Amantadine Base
tricyclo[3.3.1.1(3,7)]decan-1-ylamine
tricyclo[3.3.1.1(3,7)]decane-1-amine
Amantadinum (INN-Latin)
Amantadina (INN-Spanish)
Amantadine [INN:BAN]
AMANTADINE (MART.)
AMANTADINE [MART.]
Amant
CAS-768-94-5
tricyclo(3.3.1.1(3,7))decan-1-amine
tricyclo(3.3.1.1(3,7))decane-1-amine
tricyclo(3.3.1.1(3,7))decan-1-ylamine
40933-03-7
ADAMANTANE,1-AMINO
adamantaneamine
adamantyl amine
AmantadineHCl
1-admantaneamine
1-Amantadine
1-adamantanylamine
1-adamantyl amine
Adamant-1-ylamine
1-amino-adamantane
adamantane-1-amine
Mantadine (Salt/Mix)
Symmetrel (Salt/Mix)
1-AMINOTRICYCLO
Spectrum_000030
AMANTADINE [MI]
Tricyclo[3.3.1.1^3,7]decan-1-amine
Prestwick0_000407
Prestwick1_000407
Prestwick2_000407
Prestwick3_000407
Spectrum2_000081
Spectrum3_000291
Spectrum4_000134
Spectrum5_000772
1-Adamantylamine, 97%
AMANTADINE [HSDB]
Lopac-A-1260
Tricyclo[3.3.1.1(sup3,7)]decan-1-amine
AMANTADINE [VANDF]
SCHEMBL4098
AMANTADINE [WHO-DD]
NCIOpen2_001059
Lopac0_000004
Oprea1_248648
BSPBio_000334
BSPBio_001570
BSPBio_001822
KBioGR_000548
KBioSS_000390
BIDD:GT0757
CHEMBL19601
DivK1c_000815
Exp-105-1 (Salt/Mix)
SPBio_000002
SPBio_002273
BPBio1_000368
GTPL4128
SCHEMBL2619248
SCHEMBL15672299
SCHEMBL20409394
SCHEMBL21309814
SCHEMBL21310017
SCHEMBL23419027
KBio1_000815
KBio2_000390
KBio2_002958
KBio2_005526
KBio3_001322
NINDS_000815
HMS1791O12
HMS1989O12
HMS3604O07
HMS3887I19
1-Adamantanamine;1-Aminoadamantane
ALBB-013871
BCP09869
HY-B0402
STR04703
Tox21_110068
BDBM50033369
s5499
STK298781
AKOS000113994
AKOS000119324
AKOS007930692
AKOS015935124
Tox21_110068_1
CCG-204100
CS-W008656
DB00915
FA07678
SDCCGSBI-0049993.P005
IDI1_000815
NCGC00015036-01
NCGC00015036-02
NCGC00015036-04
NCGC00015036-05
NCGC00015036-06
NCGC00015036-07
NCGC00015036-08
NCGC00015036-09
NCGC00015036-11
NCGC00015036-13
NCGC00015036-24
NCGC00162039-01
NCGC00162039-02
NCGC00162039-03
NCGC00162039-04
NCGC00179597-01
1ST10021
AC-25879
ADS-5102, EXP 105-1
AS-14215
BP-13040
SY017655
1-Adamantanamine (purified by sublimation)
SBI-0049993.P004
WLN: L66 B6 A B- C 1B ITJ BZ
A2318
AB00514655
NS00007702
EN300-33893
tricyclo[3.3.1.1[3,7]]decane, 1-amino-
C06818
D07441
AB00053414-14
AB00053414-16
AB00053414_17
AB00053414_18
AB01275427-01
AE-641/01634060
L000868
Q409761
BRD-K70330367-003-01-2
BRD-K70330367-003-03-8
BRD-K70330367-003-07-9
BRD-K70330367-003-08-7
Q27453436
F0001-1962
InChI=1/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H
212-201-2
Solubility of Adamantan-1-amine (C10H17NH2)
Adamantan-1-amine exhibits notable characteristics regarding its solubility in various solvents. Below are key points that highlight its solubility behavior:
To summarize, adamantan-1-amine's solubility can be described as follows:
Thus, it’s interesting to note that the interplay between molecular structure and solvent polarity plays a critical role in determining the solubility profile of adamantan-1-amine.