Skip to main content

Clonidine

ADVERTISEMENT
Identification
Molecular formula
C9H9Cl2N3
CAS number
4205-91-8
IUPAC name
acetic acid;2-[6-[[amino-[[amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[amino-(4-chloroanilino)methylene]guanidine
State
State
Solid at room temperature, often used in its hydrochloride salt form for pharmaceutical applications.
Melting point (Celsius)
124.00
Melting point (Kelvin)
397.15
Boiling point (Celsius)
545.00
Boiling point (Kelvin)
818.15
General information
Molecular weight
266.15g/mol
Molar mass
266.1540g/mol
Density
1.5420g/cm3
Appearence

Clonidine typically appears as a white to off-white crystalline powder. It is often used in its hydrochloride salt form, which is soluble in water.

Comment on solubility

Solubility of Acetic Acid; 2-[6-[[Amino-[[Amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[Amino-(4-chloroanilino)methylene]guanidine

When considering the solubility of the compound with the formula C9H9Cl2N3, several factors play a pivotal role:

  • Polarity: This compound contains both polar and non-polar regions, which generally improves solubility in a variety of solvents. The presence of amino groups enhances the ability to form hydrogen bonds, allowing better interaction with polar solvents like water.
  • Hydrogen bonding: The amino groups are likely to enable strong hydrogen bonding, contributing to higher solubility in polar solvents compared to non-polar solvents.
  • Nature of substituents: The 4-chloroanilino substituent may introduce additional hydrophobic character, potentially decreasing solubility in very polar environments but enabling solubility in slightly polar organic solvents.
  • Concentration effects: At higher concentrations, solubility may be further influenced by the formation of complexes or aggregates, possibly reducing effective solubility in solutions.

In conclusion, the solubility of this compound is influenced by a combination of polarity, functional groups, and environmental conditions. Overall, expect a moderate solubility profile in polar solvents with some degree of variation based on concentration and presence of other solubilizing agents.

Interesting facts

Interesting Facts about Acetic Acid and Its Unique Derivative

Acetic acid, commonly known as vinegar when diluted, is not just a staple in culinary arts but also plays a significant role in the field of chemistry. The compound associated with acetic acid in this context is a fascinating derivative that showcases complex interactions between amino groups and halogenated aromatic systems.

Key Highlights

  • Biological Significance: Acetic acid is crucial in metabolic processes and serves as a building block for various biological molecules.
  • Versatile Applications: Beyond its culinary uses, acetic acid is utilized in the production of synthetic fibers, plastics, and as a solvent in the chemical industry.
  • Environmentally Friendly: It biodegrades effectively, making it a preferred option in ecological applications compared to more harmful solvents.
  • Unique Structure: The derivative related to acetic acid features an intricate structure with multiple amino groups, which can have significant implications for its biological activity and potential therapeutic uses.
  • Medicinal Potential: Compounds with such structure may show promise as drugs, particularly as agents targeting specific pathways in diseases.

"Understanding the complex chemistry of these derivatives is essential for advancing medicinal chemistry and developing new therapies."

This specific derivative exemplifies the creativity and complexity inherent in chemical synthesis, blending simple organic chemistry with intricate biological considerations. As researchers delve deeper into exploring its properties, it unveils new horizons in the development of novel therapeutic agents.

Synonyms
Chlorhexidine diacetate
Chlorhexidine acetate
56-95-1
MFCD00012532
Chlorhexidine Acetate,(S)
CHLORHEXIDINE DIACATATE
BCP13778
BCP18752
GIA98679
SY036251
NS00078947
Q27261630
Chlorhexidine diacetate 100 microg/mL in Acetonitrile:Water
Hibitane diacetate; MK 412A;MK-412A;MK412A;Sebidin A
1,1'-hexamethylenebis[5-(4-chloro-phenyl)biguanide] diacetate
Acetate, Chlorhexidine;MK 412A;MK412A;MK-412A;Sebidin A