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Vidarabine

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Identification
Molecular formula
C10H13N5O4
CAS number
24356-66-9
IUPAC name
9-tetrahydrofuran-2-ylpurin-6-amine
State
State
Solid at room temperature. It is primarily used in solid form for pharmaceutical applications where it provides consistent dosages.
Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.15
General information
Molecular weight
267.27g/mol
Molar mass
267.2670g/mol
Density
1.7100g/cm3
Appearence
Vidarabine appears as a white crystalline powder. It can exhibit polymorphism depending on the method of crystallization. It is typically used in pharmaceutical applications where purity in appearance is crucial.
Comment on solubility

Solubility of 9-tetrahydrofuran-2-ylpurin-6-amine (C10H13N5O4)

The solubility of 9-tetrahydrofuran-2-ylpurin-6-amine is an intriguing aspect of its chemical behavior. Several factors influence the solubility of this compound, including:

  • Polarity: The presence of polar functional groups in the molecule allows for interactions with water molecules, enhancing solubility in polar solvents.
  • Temperature: Generally, solubility increases with an increase in temperature; hence, the solubility profile may vary significantly in different thermal conditions.
  • pH of the Solution: The ionization state of amine groups can alter depending on the pH, potentially affecting the solubility in aqueous environments.
  • Solvent Choice: While it has a propensity to be soluble in polar solvents, its behavior in non-polar solvents could drastically change due to hydrophobic interactions.

Experiments show that this compound may exhibit limited solubility in water but could be more soluble in organic solvents such as DMSO or ethanol. It is often highlighted that “the solubility characteristics of compounds can reveal a lot about their reactivity and application in biological systems.”

Therefore, understanding the solubility of 9-tetrahydrofuran-2-ylpurin-6-amine is crucial for its practical uses in various chemical and pharmaceutical applications, since solubility directly influences bioavailability and therapeutic efficacy.

Interesting facts

Interesting Facts about 9-Tetrahydrofuran-2-ylpurin-6-amine

9-Tetrahydrofuran-2-ylpurin-6-amine is a fascinating compound that belongs to the category of purine derivatives. Purines are crucial in the realm of biochemistry, serving as the building blocks of essential biomolecules such as nucleic acids (DNA and RNA). Here are some intriguing aspects of this compound:

  • Structure and Function: This compound features a unique combination of a tetrahydrofuran ring fused to a purine base. Such architecture may result in interesting biochemical properties that could influence its binding interactions with various biological targets.
  • Potential Applications: Due to its purine structure, it may be of interest in medicinal chemistry, particularly in drug design aimed at targeting nucleic acid processes, enzyme inhibition, or signaling pathways.
  • Research Interest: Compounds of this nature are often studied for their potential roles in metabolism and cellular signaling. Researchers are continually unraveling the complexities of purine derivatives, including how they could be used in therapeutic settings.
  • Natural Occurrence: Purines are not just synthetic; they occur naturally in various organisms, playing vital roles in cellular energy transfer (e.g., ATP) and as components of important cofactors (e.g., NADH).
  • Analytical Techniques: The structural characterization and quantification of compounds like 9-tetrahydrofuran-2-ylpurin-6-amine often involve advanced techniques such as NMR spectroscopy and mass spectrometry, highlighting the ongoing need for analytical chemistry skills in understanding molecular structures.

In conclusion, 9-tetrahydrofuran-2-ylpurin-6-amine exemplifies the intersection of organic chemistry and biochemistry. Its unique structure not only opens the door to various research avenues but also emphasizes the importance of understanding purine chemistry in biological systems. As scientific inquiry delves deeper into this compound’s properties and mechanisms, it may illuminate new paths in pharmaceuticals and biotechnological innovations.

Synonyms
17318-31-9
9-(tetrahydrofuran-2-yl)-9h-purin-6-amine
SQ22536
SQ 22536
9-(Tetrahydro-2-furanyl)-9H-purin-6-amine
Sq 22,536
9-(Tetrahydrofuryl)adenine
9H-Purin-6-amine, 9-(tetrahydro-2-furanyl)-
9-THF-Ade
9-(oxolan-2-yl)purin-6-amine
SQ-22536
6-Amino-9-(tetrahydro-2-furyl)-9H-purine
CHEBI:90232
MFCD00210216
CHEMBL64239
MLS002667588
Adenine, 9-(tetrahydro-2-furyl)-
AX 100
Adenine, 9-(tetrahydro-2-furanyl)-
SMR001230661
9H-Purin-6-amine,9-(tetrahydro-2-furanyl)-
9-(Tetrahydrofuryl)-Adenine
Lopac0_001192
BSPBio_001142
KBioGR_000482
KBioSS_000482
MLS002153167
SCHEMBL896095
9-(Tetrahydro-2-furyl)adenine
BCBcMAP01_000102
KBio2_000482
KBio2_003050
KBio2_005618
KBio3_000883
KBio3_000884
UKHMZCMKHPHFOT-UHFFFAOYSA-N
Bio2_000411
Bio2_000891
HMS1362J03
HMS1792J03
HMS1990J03
HMS2235P22
HMS3263P05
HMS3266A19
HMS3369D08
HMS3403J03
HMS3412B05
HMS3676B05
BCP28072
EX-A1263
NSC53339
Tox21_501192
BDBM50009687
HSCI1_000170
NSC-53339
s8283
AKOS015998755
CCG-205266
CS-6136
FS-6588
LP01192
SDCCGSBI-0051159.P002
IDI1_002166
NCGC00015912-02
NCGC00015912-03
NCGC00015912-04
NCGC00015912-05
NCGC00015912-06
NCGC00015912-07
NCGC00015912-12
NCGC00094445-01
NCGC00094445-02
NCGC00094445-03
NCGC00094445-04
NCGC00094445-05
NCGC00261877-01
AC-32734
DA-77991
FT155955
SQ22536?
HY-100396
EU-0101192
Q0105
S-153
SQ 22,536, >=97% (HPLC), powder
M02495
P10102
9-(Tetrahydro-furan-2-yl)-9H-purin-6-ylamine
SR-01000075521
SR-01000075521-1
BRD-A56987319-001-03-8
BRD-A56987319-001-05-3
BRD-A56987319-001-12-9
Q27162414
SQ 22536 - CAS 17318-31-9
SQ22536; SQ 22536; SQ-22,536; SQ22,536; SQ 22,536