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Tenofovir

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Identification
Molecular formula
C9H14N5O4P
CAS number
202138-50-9
IUPAC name
9-tetrahydrofuran-2-yl-7H-purin-9-ium-6-amine
State
State

At room temperature, Tenofovir is typically in a solid state as a white to off-white crystalline powder.

Melting point (Celsius)
274.00
Melting point (Kelvin)
547.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
636.52g/mol
Molar mass
636.5170g/mol
Density
1.4900g/cm3
Appearence

The compound generally appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 9-tetrahydrofuran-2-yl-7H-purin-9-ium-6-amine (C9H14N5O4P)

The solubility of 9-tetrahydrofuran-2-yl-7H-purin-9-ium-6-amine can be characterized by several key factors:

  • Polarity: The presence of a purine base structure indicates that the compound may have considerable polarity, which often influences its interactions with solvents.
  • Functional Groups: Functional groups such as amines and the tetrahydrofuran ring contribute to potential solvation. Amines are generally soluble in water, enhancing the likelihood of this compound’s solubility in polar solvents.
  • Solvent Types: It may be more soluble in aqueous environments or organic solvents that can form hydrogen bonds, which could facilitate its dissolution.
  • Temperature Dependence: Solubility can also increase with temperature—a common trend observed in many chemical compounds.

Overall, while the specific solubility data for this compound may need to be experimentally determined, it is reasonable to conclude that it exhibits solubility characteristics influenced by its molecular structure and the nature of the solvents used. As complicated compounds often reveal interesting solubility profiles, further investigation into polar vs. non-polar solvents could provide more insights.


Interesting facts

Interesting Facts about 9-Tetrahydrofuran-2-yl-7H-purin-9-ium-6-amine

The compound 9-tetrahydrofuran-2-yl-7H-purin-9-ium-6-amine is a fascinating member of the purine family, which is notable for its role in various biological processes. Here are some key points that underscore its significance:

  • Biological Importance: Purines, including this compound, serve as essential building blocks for nucleotides—the molecules that make up DNA and RNA. This highlights the compound's potential impact on genetic research and biotechnology.
  • Pharmaceutical Applications: Many purine derivatives are known for their pharmacological properties. This specific compound may have implications in drug design, particularly in treatments related to cancer and antiviral therapies.
  • Structure and Stability: The incorporation of a tetrahydrofuran ring adds a unique structural element, influencing the compound's stability and reactivity. This complexity allows chemists to explore various synthetic pathways and modifications.
  • Research Potential: As researchers delve deeper into the mechanisms of action of purine compounds, 9-tetrahydrofuran-2-yl-7H-purin-9-ium-6-amine may reveal novel insights, leading to the development of new therapeutic agents.

As chemists continue to explore the myriad possibilities within the realm of purines, compounds like 9-tetrahydrofuran-2-yl-7H-purin-9-ium-6-amine represent exciting avenues for academic inquiry and practical application.

Synonyms
Bio1_001285
CBiol_002021
Bio1_000307
Bio1_000796
SMP2_000106