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Mitraphylline

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Identification
Molecular formula
C22H30N2O4
CAS number
483-03-8
IUPAC name
9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
State
State

At room temperature, Mitraphylline is a solid compound, appearing as a white to off-white crystalline powder. It is stable under normal conditions and should be stored in a cool, dry place.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
384.50g/mol
Molar mass
384.4970g/mol
Density
1.3300g/cm3
Appearence

Mitraphylline is typically a crystalline solid that appears in white or off-white color.

Comment on solubility

Solubility of 9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol

The solubility of chemical compounds is a crucial aspect that influences their behavior in various environments. For the compound 9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol (C22H30N2O4), we consider several key factors that affect its solubility:

  • Molecular Structure: The presence of multiple functional groups, such as methoxy and hydroxyl groups, suggests potential for hydrogen bonding, which may enhance solubility in polar solvents.
  • Polarity: The overall polarity of the molecule plays a significant role. Substances that are more polar tend to be more soluble in polar solvents, while non-polar compounds are usually soluble in non-polar solvents.
  • Size and Weight: With a relatively large molecular weight (C22H30N2O4), the compound may display reduced solubility in water compared to smaller molecules, particularly if it also possesses significant hydrophobic characteristics.

In summary, while specific experimental solubility data for this particular compound may not be readily available, one can hypothesize:

  1. High likelihood of moderate solubility in organic solvents due to hydrophobic regions.
  2. Possible limited solubility in water because of its complex structure and significant size.
  3. The profile of solubility may also change when considering different temperatures or in the presence of various solubilizing agents.

Ultimately, understanding solubility is essential, not only for predicting behaviors in chemical reactions but also for applications in fields such as pharmacology, where proper dissolution is necessary for bioavailability.

Interesting facts

Interesting Facts About 9-Methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol

This compound is a fascinating member of the isoquinoline family, showcasing its significant potential in both chemistry and pharmacology. Here are some key points to consider:

  • Structural Complexity: The unique structure of this compound features a complex arrangement of fused rings, which is characteristic of many alkaloids. Such intricate frameworks often result in distinctive biological activities.
  • Alkaloid Class: Alkaloids are known for their diverse range of pharmacological properties, including anti-inflammatory, analgesic, and antitumor effects. This compound may hold similar potential, warranting further exploration.
  • Natural Sources: Compounds with similar structures can often be derived from various plant sources, which traditionally have been used in herbal medicine. Investigation into natural sources could lead to sustainable extraction methods.
  • Research Interest: The compound's unique properties make it a subject of interest in drug design and discovery, particularly in the context of synthesizing novel therapeutic agents.
  • Potential Uses: Beyond medicinal chemistry, its unique properties may find applications in materials science, such as developing novel polymers or nanomaterials.

As you delve deeper into the world of compounds like this one, remember the words of renowned chemist Marie Curie: "Nothing in life is to be feared, it is only to be understood." Continuous research and study can unlock the secrets hidden in such complex chemical structures.

In summary, 9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol represents a treasure trove of opportunities for those curious about the intersection of chemistry and biological activity.

Synonyms
Dihydroneopine
Drocode
Dihydrin
Codeine, dihydro-
6.alpha.-Hydrocodol
Hydrocodin
Paracodine
Didrate
Paracodin
Parzone
(-)-Dihydrocodeine
7,8-Dihydrocodeine
Morphinan-6.alpha.-ol, 4,5.alpha.-epoxy-3-methoxy-17-methyl-
6-Hydroxy-3-methoxy-N-methyl-4,5-epoxymorphinan
Rapocodin
Dihydrocodeine bitartrate (Salt/Mix)
Codeine, dihydro
Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5.alpha.,6.alpha.)-
3-methoxy-17-methyl-4,5-epoxymorphinan-6-ol
6?-Hydrocodol
SCHEMBL6123622
CHEMBL4765015
DTXSID80859235
4,5.alpha.-Epoxy-3-methoxy-17-methylmorphinan-6.alpha.-ol (+)-tartrate (salt) (Salt/Mix)
AAA79538
Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5.alpha.,6.alpha.)-2,3-dihydroxybutanedioate (1:1) (salt) (Salt/Mix)
NSC231319
NS00124910
Morphinan-6.alpha.-ol,5.alpha.-epoxy-3-methoxy-17-methyl-
WLN: T B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ FQ JO1 P1
Morphinan-6-ol,5-epoxy-3-methoxy-17-methyl-, (5.alpha.,6.alpha.)-