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Clomipramine

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Identification
Molecular formula
C19H23ClN2O
CAS number
303-49-1
IUPAC name
9-chloro-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,8-triene-10,11-dione
State
State

In its most common form, clomipramine is a solid at room temperature. It is stable under normal conditions and should be stored in a cool, dry place.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.15
Boiling point (Celsius)
442.56
Boiling point (Kelvin)
715.71
General information
Molecular weight
313.87g/mol
Molar mass
313.8670g/mol
Density
1.1500g/cm3
Appearence

Clomipramine is a white to off-white crystalline powder. It is usually odorless and tasteless, with a very fine consistency.

Comment on solubility

Solubility of 9-chloro-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,8-triene-10,11-dione

The solubility of 9-chloro-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,8-triene-10,11-dione (C19H23ClN2O) is influenced by several factors, primarily related to its structural characteristics. This compound features a complex tricyclic framework and halogen substitution, both of which play significant roles in determining its solubility.

Key aspects of its solubility profile include:

  • The presence of a chloro group, which often increases the polarity of organic compounds, suggesting potential solubility in polar solvents.
  • The overall number of carbon atoms in the compound may contribute to its hydrophobic characteristics, implying limited solubility in water.
  • Interactions with solvent molecules, such as hydrogen bonding or dipole-dipole interactions, may further delineate its solubility across different mediums.

It is often observed that while similar compounds may have varied solubility ranges, those that are larger and more complex, like C19H23ClN2O, could exhibit:

  • Limited solubility in water
  • Higher solubility in organic solvents, such as ethanol or acetone, due to their nonpolar or mildly polar nature.

In conclusion, the solubility of this compound is likely to exhibit a dual nature wherein it is less soluble in aqueous solutions, yet potentially soluble in various organic solvents, aligning with common trends observed in similar tri- and bicyclic compounds. Understanding the solubility can greatly aid in predicting its behavior in different chemical environments.

Interesting facts

Interesting Facts about 9-Chloro-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,8-triene-10,11-dione

This intriguing compound, known for its complex structure and unique properties, presents a fascinating area of study in the field of chemistry. Here are some interesting aspects of this compound:

  • Complex Framework: The compound features a distinctive bicyclic framework with multiple rings, specifically a tricyclic structure, that can engage in various chemical reactions.
  • Diversity in Applications: Its structure suggests potential applications in medicinal chemistry, especially given the presence of chlorine and other functional groups that could contribute to bioactivity.
  • Reactivity: The 10,11-dione functionality indicates that it may undergo nucleophilic attack and other sorts of transformations, making it versatile for synthetic applications.
  • Research Interest: Scientists are particularly interested in compounds like this due to their potential to lead to novel drug candidates, especially in combating diseases where conventional therapies may fail.
  • Synthetic Challenges: The synthesis of such complex molecules often requires advanced techniques, including multi-step synthesis and careful manipulation of reaction conditions.

As a chemistry student or researcher, exploring compounds like 9-chloro-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,8-triene-10,11-dione not only bolsters one’s understanding of organic chemistry but also contributes to the advancement of chemical science as a whole. It’s a reminder of the beauty and intricacies present in the molecular world!

Synonyms
Batzelline C
123064-91-5
Pyrrolo(4,3,2-de)quinoline-7,8-dione, 6-chloro-1,3,4,5-tetrahydro-1-methyl-
DTXSID10153854
9-chloro-2-methyl-2,7-diazatricyclo(6.3.1.04,12)dodeca-1(12),3,8-triene-10,11-dione
9-chloro-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,8-triene-10,11-dione
Pyrrolo[4,3,2-de]quinoline-7,8-dione, 6-chloro-1,3,4,5-tetrahydro-1-methyl-
chloro(methyl)[?]dione
DTXCID9076345
NSC700002
NSC-700002