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2'-Deoxyadenosine 5'-monophosphate

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Identification
Molecular formula
C10H14N5O6P
CAS number
653-63-0
IUPAC name
[9-[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]purin-6-yl] dihydrogen phosphate
State
State

At room temperature, 2'-Deoxyadenosine 5'-monophosphate is a solid. It is stable under normal temperatures and pressures.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
331.22g/mol
Molar mass
331.2240g/mol
Density
2.0000g/cm3
Appearence

2'-Deoxyadenosine 5'-monophosphate typically appears as a white crystalline solid or powder. Its hygroscopic nature means it can absorb moisture from the air under humid conditions.

Comment on solubility

Solubility of [9-[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]purin-6-yl] dihydrogen phosphate

This compound, with the chemical formula C10H14N5O6P, presents interesting solubility characteristics due to its unique functional groups. In general, the solubility of a compound can be influenced by several factors, which in this case might include:

  • Polarity: The presence of multiple hydroxyl groups and phosphate groups suggests that this compound is highly polar, which often translates to good solubility in polar solvents such as water.
  • Hydrogen Bonding: The numerous -OH groups enhance its ability to participate in hydrogen bonding with solvent molecules, further promoting solubility.
  • Ionization: The phosphonato group may lead to ionization in aqueous solutions, improving solubility due to increased molecular interactions with water.

Given these factors, it is expected that this compound is readily soluble in aqueous environments, a characteristic that can be advantageous for biological systems and potential pharmaceutical applications. In summary, one can conclude that:

"High polarity and the potential for hydrogen bonding are key drivers of solubility in this compound."

For practical applications, understanding its solubility is crucial as it affects bioavailability and transport in biological systems. Further studies may be warranted to confirm specific solubility measurements under various conditions.

Interesting facts

Interesting Facts About [9-[3,4-Dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]purin-6-yl] Dihydrogen Phosphate

This compound, often referred to as a derivative of purine, has garnered attention in the field of biochemistry due to its potential roles in cellular metabolism and signaling. Here are some engaging points that shed light on its significance:

  • Biological Relevance: The unique structural features of this compound may influence its biological activity. Purine derivatives are crucial components of various biological processes, including DNA and RNA synthesis.
  • Phosphorylation Role: The presence of phosphate groups in this molecule is essential for energy transfer and storage. Indeed, phosphate plays a pivotal role in energy currency in cells, particularly through ATP.
  • Potential Therapeutic Applications: Research suggests that compounds similar to this one could develop into therapeutic agents. Their ability to modify biological pathways could be harnessed for treatment strategies in metabolic and cardiovascular diseases.
  • Structural Intricacies: The presence of a tetrahydrofuran ring adds an intriguing aspect to its chemical structure, making it an interesting candidate for studying ring-opening reactions and stereochemical properties.
  • Natural Analogues: This compound can be studied alongside naturally occurring nucleotides, revealing how modifications can alter molecular behavior and interaction with enzymatic systems.

As scientists continue to explore the characteristics and functions of [9-[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]purin-6-yl] dihydrogen phosphate, it stands to represent the intricate relationship between chemistry and biology. Discoveries about how such compounds interact with biomolecules may pave the way for innovations in drug design and understanding disease mechanisms.

Synonyms
PD041263