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Xanthosine

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Identification
Molecular formula
C10H12N4O6
CAS number
146-80-5
IUPAC name
9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purine-2,6-dione
State
State

At room temperature, xanthosine is in a solid state. It is typically stable under standard conditions of temperature and pressure.

Melting point (Celsius)
375.00
Melting point (Kelvin)
648.00
Boiling point (Celsius)
800.00
Boiling point (Kelvin)
1 073.00
General information
Molecular weight
298.25g/mol
Molar mass
298.2460g/mol
Density
2.0300g/cm3
Appearence

Xanthosine appears as a white to off-white crystalline powder. It is odorless and is typically used in biochemical studies.

Comment on solubility

Solubility of 9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purine-2,6-dione

The solubility of the compound C10H12N4O6 can significantly impact its applications in both biochemical and pharmaceutical fields. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple hydroxyl groups in its structure typically increases polarity, which often enhances solubility in polar solvents, especially water.
  • Hydrogen bonding: The -OH groups are capable of forming hydrogen bonds, which can further improve solubility by interacting with solvent molecules.
  • pH dependence: Solubility can vary with pH, as ionizable protons in the molecule may affect its overall charge and solubility profile in aqueous environments.
  • Temperature effects: Higher temperatures generally increase solubility for most solids due to increased molecular motion, which can be an essential consideration in practical applications.

In summary, while specific solubility data for this compound may vary, it is likely to be soluble in polar solvents due to its functional groups. This characteristic is critical for its use in various biological pathways and while formulating pharmaceutical preparations.

Interesting facts

Interesting Facts About 9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purine-2,6-dione

This intriguing compound, often referenced in biochemical studies, has significant implications in various fields, primarily due to its structural and functional attributes. Here are some captivating insights:

  • Biological Relevance: This compound is known to mimic the structure of purines, which are essential components of nucleic acids. This allows it to play potential roles in nucleotide metabolism.
  • Enzymatic Activity: It can act as a substrate or inhibitor for several enzymes, making it a focal point for research in enzymology and pharmacology.
  • Natural Derivative: The compound is a modification of naturally occurring purine derivatives, which are crucial in many biological processes, including DNA and RNA synthesis.
  • Therapeutic Potential: Its applications in medicinal chemistry highlight its potential as a therapeutic agent, especially in targeting various diseases that result from nucleic acid anomalies.
  • Research Focus: Ongoing research is investigating its efficacy in drug design, especially concerning its ability to interact with biological macromolecules effectively.

As you delve deeper into the world of this purine derivative, one cannot help but appreciate the intricate balance between structure and function in biochemistry. The quote, "Understanding the language of molecular structures is key to unlocking the secrets of life itself," perfectly encapsulates the allure this compound holds in scientific exploration.

In summary, the study of 9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purine-2,6-dione not only demonstrates the complexity of chemical interactions but also opens up avenues for future therapeutic innovations.

Synonyms
9-.beta.-D-Ribofuranosylxanthine
.beta.-D-Ribofuranoside, xanthine-9
9-pentofuranosyl-3,9-dihydro-1H-purine-2,6-dione
MFCD00005726
SCHEMBL6676995
CHEMBL1880013
SCHEMBL21602879
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-2,6-dione
NSC18930
STK246877
STK681920
9-pentofuranosyl-9H-purine-2,6-diol
AKOS005422623
AKOS005596524
NCGC00161976-01
LS-13790
SY073035
NS00007495
L000880
SR-01000091574
SR-01000091574-1
1H-Purine-2, 3,9-dihydro-9-.beta.-D-ribofuranosyl-
Z2651719377
9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-6-hydroxy-3H-purin-2(9H)-one?NSC 18930; STK246877; STK681920